Yıl: 2020 Cilt: 21 Sayı: 1 Sayfa Aralığı: 33 - 36 Metin Dili: İngilizce DOI: 10.4274/imj.galenos.2019.48992 İndeks Tarihi: 06-10-2020

Endoscopic Approach to Esophageal Leiomyomas: Single Center Results

Öz:
Introduction: Leiomyoma is the most common esophagealbenign lesion. There are many treatment methods fromendoscopic treatment methods to surgery in the treatmentof leiomyoma. In this study, we evaluated the results of ourpatients who underwent endoscopic mucosal (EMR) andsubmucosal dissection (ESD) due to esophageal leiomyoma.Methods: A total of 18 patients who underwent EMR or ESDprotocol with the diagnosis of esophageal leiomyoma wereincluded in the study and age, gender, radiological imagingresults, endoscopic ultrasonography results, treatmentmethod, pathology results, and outpatient follow-up data ofthe patients were recorded following retrospective examinationof the patient files.Results: The mean age of the patients was 52.7±13.36 years,and the ratio of female/male was 1/1.25. Incidental lesionswere found during endoscopic procedures in six patients(33.3%) due to dyspeptic complaints and in three patients(16.7%) due to dysphagia and during computed tomographyin the remaining nine patients (50%) for various reasons. Fortreatment, three patients underwent EMR, and 15 patientsunderwent ESD. One patient had a hemorrhage controlled byendoscopic intervention, and no other complications wereobserved after treatment.Conclusion: It should be kept in mind that ESD and EMR,which are among the endoscopic treatment methods in thetreatment of esophageal leiomyoma, could be safely appliedin experienced hands.
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Özofagus Leyomiyomlarında Endoskopik Yaklaşım: Tek Merkez Sonuçları

Öz:
Amaç: En sık gözlenen özofagus benign lezyonları leiomiyomlardır. Leiomiyomların tedavisinde endoskopik tedavi yöntemlerinden cerrahiye kadar birçok tedavi yöntemi bulunmaktadır. Biz de bu çalışmamızda özofagus leiomiyomu sebebiyle endoskopik mukozal (EMR) ve submukozal rezeksiyon (ESD) yapılan hastalarımızın sonuçlarını değerlendirdik. Yöntemler: Özofageal leiomiyom tanısı ile EMR veya ESD protokolü uygulanan toplam 18 hasta çalışmaya dahil edilmiş olup hastaların hastane dosyalarının retrospektif olarak incelenmesi sonucunda hastaların yaşları, cinsiyetleri, radyolojik görüntüleme sonuçları, endoskopik ultrasonografi sonuçları, uygulanan tedavi yöntemi, patoloji sonuçları ve hastaların poliklinik takip notları kayıt altına alınmıştır. Bulgular: Hastaların ortalama yaşı 52,7±13,36 yıl olup kadın/ erkek oranı 1/1,25’tir. Hastaların 6’sında (%33,3) dispeptik şikayetler nedeniyle yapılan tetkiklerde, 3’ünde (%16,7) disfaji nedeniyle yapılan endoskopik girişimler sırasında, diğer 9 hastada (%50) ise çeşitli sebeplerle çekilen bilgisayarlı tomografiler sırasında insidental olarak lezyonlar bulunmuştur. Tedavi için 3 hastaya EMR, 15 hastaya ise ESD uygulanmıştır. Tedavi sonrası 1 hastada endoskopik müdahale ile durdurulan kanama mevcut olup başka bir komplikasyon gözlenmemiştir. Sonuç: Özofagus leiomiyomlarının tedavisinde endoskopik tedavi yöntemlerinden olan ESD ve EMR’nin tecrübeli ellerde güvenle uygulanabileceği akılda bulundurulmalıdır.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • 1. Jiang W, Rice TW, Goldblum JR. Esophageal leiomyoma: experience from a single institution. Dis Esophagus 2013; 26: 167-74.
  • 2. Seremetis MG, Lyons WS, DeGuzman VC, Peabody JW Jr. Leiomyomata of the esophagus. An analysis of 838 cases. Cancer 1976; 38: 2166-77.
  • 3. Wang L, Ren W, Zhang Z, Yu J, Li Y, Song Y. Retrospective study of endoscopic submucosal tunnel dissection (ESTD) for surgical resection of esophageal leiomyoma. Surg Endosc 2013; 27: 4259-66.
  • 4. Mutrie CJ, Donahue DM, Wain JC, Wright CD, Gaissert HA, Grillo HC, et al. Esophageal leiomyoma: A 40-year experience. Ann Thorac Surg 2005; 79: 1122-5.
  • 5. Buyruk M, Vardar R. Endoskopik mukozal rezeksiyon ve endoskopik submukozal diseksiyon: Kime? Ne zaman? Güncel Gastroenteroloji 2018; 22: 7-17.
  • 6. Bonavina L, Segalin A, Rosati R, Pavanello M, Peracchia A. Surgical therapy of esophageal leiomyoma. J Am Coll Surg 1995; 181: 257-62.
  • 7. Choi SH, Kim YT, Han KN, Ra YJ, Kang CH, Sung SW, et al. Surgical management of the esophageal leiomyoma: Lessons from a retrospective review. Dis Esophagus 2011; 24: 325-9.
  • 8. Bardini R, Segalin A, Ruol A, Pavanello M, Peracchia A. Videothoracoscopic enucleation of esophageal leiomyoma. Ann Thorac Surg 1992; 54: 576-7.
  • 9. Izumi Y, Inoue H, Endo M. Combined endoluminal-intracavitary thoracoscopic enucleation of leiomyoma of the esophagus. A new method. Surg Endosc 1996; 10: 457-8.
  • 10. Sun LJ, Chen X, Dai YN, Xu CF, Ji F, Chen LH, et al. Endoscopic ultrasonography in the diagnosis and treatment strategy choice of esophageal leiomyoma. Clinics (Sao Paulo) 2017; 72: 197-201.
  • 11. Cakar E, Bektas H, Duzkoylu Y, Bayrak S, Pasaoglu E, Colak S, et al. Benign cysts and tumors of esophagus: Case series and review of the literature. SurgChron 2013; 18: 151-4.
  • 12. Kramer M D, Gibb S P, Ellis F H Jr. Giant leiomyoma of esophagus. J Surg Oncol 1986; 33: 166-9.
  • 13. Postlethwait RW, Musser AW. Changes in the esophagus in 1000 autopsy specimens. J Thorac Cardiovasc Surg 1974; 68: 953-6.
  • 14. Hatch G F 3rd, Wertheimer-Hatch L, Hatch K F, Davis GB, Blanchard DK, Foster RS Jr, et al. Tumors of the esophagus. World J Surg 2000; 24: 401-11.
  • 15. Priego P, Lobo E, Alonso N, Gil Olarte MA, Pérez de Oteyza J, Fresneda V. Surgical treatment of esophageal leiomyoma: An analysis of our experience. Rev Esp Enferm Dig 2006; 98: 350-8.
  • 16. Roviaro GC, Maciocco M, Varoli F, Rebuffat C, Vergani C, Scarduelli A. Videothoracoscopic treatment of oesophageal leiomyoma. Thorax 1998; 53: 190-2.
  • 17. Wang Y-j, Zhang R, Ouyang Z, Zhang D, Wang L. Diagnosis and surgical treatment of esophageal leiomyoma. Zhonghua zhong liu za zhi .Chinese J Oncol 2002; 24: 394-6.
  • 18. Pompeo E, Francioni F, Pappalardo G, Trentino P, Crucitti G, Ricci C. Giant leiomyoma of the esophagus and cardia. Diagnostic and therapeutic considerations: Case report and literature review. Scand Cardiovasc J 1997; 31: 361-4.
  • 19. Rice T W. Benign esophageal tumors: Esophagoscopy and endoscopic esophageal ultrasound. Semin Thorac Cardiovasc Surg 2003; 15: 20-6.
  • 20. Jang K M, Lee K S, Lee S J, Kim EA, Kim TS, Han D, et al. The spectrum of benign esophageal lesions: imaging findings. Korean J Radiol 2002; 3: 199-210.
  • 21. Lee L S, Singhal S, Brinster C J, Marshall B, Kochman ML, Kaiser LR, et al. Current management of esophageal leiomyoma. J Am Coll Surg 2004; 198: 136-46.
  • 22. Isik A, Firat D, Peker K, Sayar I, Idiz O, Soytürk M. A case report of esophageal perforation: Complication of nasogastric tube placement. Am J Case Rep 2014; 15: 168-71.
  • 23. Kim SH, Moon JS, Youn YH, Lee KM, Lee SJ. Management of the complications of endoscopic submucosal dissection. World J Gastroenterol 2011; 17: 3575-9.
  • 24. Schlachterman A, Yang D, Goddard A, Gotoda T, Draganov PV. Perspectives on endoscopic submucosal dissection training in the United States: A survey analysis. Endosc Int Open 2018; 6: 399-409.
  • 25. Friedel D, Stavropoulos SN. Introduction of endoscopic submucosal dissection in the West. World J Gastrointest Endosc 2018; 10: 225-38.
APA çakar e, Idiz U, Colak S, KÖKSAL A, YARIKKAYA E, Bektaş H (2020). Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. , 33 - 36. 10.4274/imj.galenos.2019.48992
Chicago çakar ekrem,Idiz Ufuk Oguz,Colak Sukru,KÖKSAL Ayhan,YARIKKAYA Enver,Bektaş Hasan Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. (2020): 33 - 36. 10.4274/imj.galenos.2019.48992
MLA çakar ekrem,Idiz Ufuk Oguz,Colak Sukru,KÖKSAL Ayhan,YARIKKAYA Enver,Bektaş Hasan Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. , 2020, ss.33 - 36. 10.4274/imj.galenos.2019.48992
AMA çakar e,Idiz U,Colak S,KÖKSAL A,YARIKKAYA E,Bektaş H Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. . 2020; 33 - 36. 10.4274/imj.galenos.2019.48992
Vancouver çakar e,Idiz U,Colak S,KÖKSAL A,YARIKKAYA E,Bektaş H Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. . 2020; 33 - 36. 10.4274/imj.galenos.2019.48992
IEEE çakar e,Idiz U,Colak S,KÖKSAL A,YARIKKAYA E,Bektaş H "Endoscopic Approach to Esophageal Leiomyomas: Single Center Results." , ss.33 - 36, 2020. 10.4274/imj.galenos.2019.48992
ISNAD çakar, ekrem vd. "Endoscopic Approach to Esophageal Leiomyomas: Single Center Results". (2020), 33-36. https://doi.org/10.4274/imj.galenos.2019.48992
APA çakar e, Idiz U, Colak S, KÖKSAL A, YARIKKAYA E, Bektaş H (2020). Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. İstanbul Medical Journal, 21(1), 33 - 36. 10.4274/imj.galenos.2019.48992
Chicago çakar ekrem,Idiz Ufuk Oguz,Colak Sukru,KÖKSAL Ayhan,YARIKKAYA Enver,Bektaş Hasan Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. İstanbul Medical Journal 21, no.1 (2020): 33 - 36. 10.4274/imj.galenos.2019.48992
MLA çakar ekrem,Idiz Ufuk Oguz,Colak Sukru,KÖKSAL Ayhan,YARIKKAYA Enver,Bektaş Hasan Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. İstanbul Medical Journal, vol.21, no.1, 2020, ss.33 - 36. 10.4274/imj.galenos.2019.48992
AMA çakar e,Idiz U,Colak S,KÖKSAL A,YARIKKAYA E,Bektaş H Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. İstanbul Medical Journal. 2020; 21(1): 33 - 36. 10.4274/imj.galenos.2019.48992
Vancouver çakar e,Idiz U,Colak S,KÖKSAL A,YARIKKAYA E,Bektaş H Endoscopic Approach to Esophageal Leiomyomas: Single Center Results. İstanbul Medical Journal. 2020; 21(1): 33 - 36. 10.4274/imj.galenos.2019.48992
IEEE çakar e,Idiz U,Colak S,KÖKSAL A,YARIKKAYA E,Bektaş H "Endoscopic Approach to Esophageal Leiomyomas: Single Center Results." İstanbul Medical Journal, 21, ss.33 - 36, 2020. 10.4274/imj.galenos.2019.48992
ISNAD çakar, ekrem vd. "Endoscopic Approach to Esophageal Leiomyomas: Single Center Results". İstanbul Medical Journal 21/1 (2020), 33-36. https://doi.org/10.4274/imj.galenos.2019.48992