Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?

yektaş, abdulkadir; Uzundere, Osman; andan, cengiz; Kaçar, Cem Kıvılcım

doi:10.4274/imj.galenos.2019.59354

Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?

Osman UZUNDERE, (Diyarbakır Kadın Hastalıkları ve Doğum Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, Diyarbakır, Türkiye)

Cem Kıvılcım KAÇAR, (Sağlık Bilimleri Üniversitesi, Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, Diyarbakır, Türkiye)

Cengiz ANDAN, (Diyarbakır Kadın Hastalıkları ve Doğum Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Diyarbakır, Türkiye)

Abdulkadir YEKTAŞ (Sağlık Bilimleri Üniversitesi, Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi, Genel Yoğun Bakım Ünitesi Kliniği, Diyarbakır, Türkiye)

İstanbul Medical Journal

0 0

Yıl: 2020 Cilt: 21 Sayı: 1 Sayfa Aralığı: 53 - 57 Metin Dili: İngilizce DOI: 10.4274/imj.galenos.2019.59354 İndeks Tarihi: 06-10-2020

Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?

Öz:

Introduction: The primary aim of our study was to investigatethe relationship between hypertensive diseases of pregnancy(HDP) and blood groups. Our secondary aim is to determinethe risk factors that play a role in the development of HDP.Methods: Pregnant women aged 15-49 years were includedin this cross-sectional, observational, and prospective study.Pregnant women were divided into two groups. Group 1(n=266) included patients admitted to the intensive care unitdue to HDP. Group 2 (n=402) included normotensive patientswithout any complications during pregnancy. The groups werecompared in terms of age, blood groups, Rh factor, gravida,parity, gestational week, and primiparity-multiparity.Results: There was no statistically significant differencebetween the groups in terms of ABO blood group and Rh factor.The mean age, gravida, and parity were significantly higher inGroup 1 than in Group 2 (p=0.028; 0.001; 0.004, respectively),while mean gestational age was lower than Group 2 (p<0.001).We also found that high gravida, low gestational age, presenceof comorbidity, and primiparity were risk factors for HDP.Conclusion: We did not find any relationship between HDPand blood groups. We found that high gravida, low gestationalage, presence of comorbidity, and primiparity are risk factorsfor HDP.

Anahtar Kelime:

ABO Kan Grupları ve Rh Faktörü Gebeliğin Hipertansif Hastalıkları için Risk Faktörü mü?

Öz:

Amaç: Çalışmamızın öncelikli amacı gebeliğin hipertansif hastalıkları (GHH) ile kan grupları arasındaki ilişkiyi incelemektir. İkincil amacımız ise GHH’lerin gelişiminde rol oynayan risk faktörlerini belirlemektir. Yöntemler: Kesitsel, gözlemsel ve prospektif olarak planlanan çalışmamıza 15-49 yaş arası gebeler dahil edildi. Gebeler iki gruba ayrıldı. Grup 1 (n=266), GHH nedeniyle yoğun bakım ünitesine kabul ettiğimiz hastalar; grup 2 (n=402), gebelik süresince herhangi bir komplikasyon gelişmeyen ve normotansif olan hastalardan oluştu. Gruplar yaş, kan grupları, Rh faktörü, gravida, parite, gebelik haftası ve primiparitemultiparite açısından karşılaştırıldı. Bulgular: Gruplar arasında ABO kan grubu ve Rh faktörü açısından istatistiksel olarak anlamlı bir fark saptanmadı. Grup 1’in yaş, gravida ve parite ortalaması grup 2’ye göre istatistiksel olarak anlamlı bir şekilde daha yüksek saptanırken (sırasıyla, p=0,028; 0,001; 0,004), gebelik haftası ortalaması grup 2’ye göre daha düşük idi (p<0,001). Ayrıca yüksek gravida, düşük gebelik haftası, komorbidite varlığı ve primiparitenin GHH için risk faktörleri olduğunu saptadık. Sonuç: Çalışmamızda GHH ile kan grupları arasında herhangi bir ilişki saptamadık. Yüksek gravida, düşük gebelik haftası, komorbidite varlığı ve primiparitenin GHH için risk faktörleri olduğunu gösterdik.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Duckitt K, Harrington D. Risk factors for pre-eclampsia at antenatal booking: Systematic review of controlled studies. BMJ 2005; 330: 565.
2. Abalos E, Cuesta C, Carroli G, Qureshi Z, Widmer M, Vogel JP, et al. “Preeclampsia, eclampsia and adverse maternal and perinatal outcomes: A secondary analysis of the World Health Organization Multicountry Survey on Maternal and Newborn Health. BJOG 2014; 121 (Suppl 1): 14-24.
3. Mirkovic L, Nejkovic L, Micic J. A new pathophysiological concept and new classification of pre-eclampsia. Vojnosanit Pregl 2018; 75: 83-94.
4. American College of Obstetricians and Gynecologists, issuing body. [DNLM: 1. Hypertension, Pregnancy-Induced-Practice Guideline. WQ 244] RG575.5 618.3’6132-dc23, 2013022521.
5. Mital P, Gupta D, Benwal DK, Gangwal H, Hooja N, Agarwal S, et al. To find any association of maternal blood group as a risk factor for preeclampsia. Int J Community Med Public Health 2016; 3: 3445-49.
6. Larsen TB, Johnsen SP, Gislum M, Møller CA, Larsen H, Sørensen HT. ABO blood groups and risk of venous thromboembolism during pregnancy and the puerperium. A population-based, nested case - control study. J Thromb Haemost 2005; 3: 300-4.
7. Capuzzo E, Bonfanti C, Frattini F, Montorsi P, Turdo R, Previdi MG, et al. The relationship between ABO blood group and cardiovascular disease: Results from the Cardiorisk program. Ann Transl Med 2016; 4: 189.
8. Franchini M, Marano G, Vaglio S, Catalano L, Pupella S, and Liumbruno G. M. The role of ABO blood type in thrombosis scoring systems. Semin Thromb Hemost 2017; 43: 525-9.
9. Hentschke MR, Caruso FB, Paula LG, Medeiros AK, Gadonski G, Antonello IC, et al. Is there any relationship between ABO/Rh blood group and patients with pre-eclampsia? Pregnancy Hypertens 2014; 4: 170-3.
10. Aghasadeghi F, Saadat M. Association between ABO and Rh blood groups and risk of preeclampsia: A case-control study from Iran. Open Access Maced J Med Sci 2017; 5: 173-6.
11. Beyazit F, Pek E, Güngör AÇ, Gencer M, Unsal MA. Effect of maternal ABO blood type on birth weight and preeclampsia. Int J Reprod Contracept Obstet Gynecol 2017; 6: 2164-7.
12. Sharami SH, Zendehdel M, Mirblouk F, Asgharnia M, Faraji R, Heirati SFD, et al. Comparison of preeclampsia risk factors regarding to severity with control group. Zahedan J Res Med Sci 2017; 19:e5008.
13. Elmugabil A, Rayis DA, Ahmed MA, Adam I, Gasim GI. O blood group as risk factor for preeclampsia among Sudanese women. Open Access Maced J Med Sci 2016; 4: 603-6.
14. Phaloprakarn C, Tangjitgamol S. Maternal ABO blood group and adverse pregnancy outcomes. J Perinatol 2013; 33: 107-11.
15. Lee BK, Zhang Z, Wikman A, Lindqvist PG, Reilly M. ABO and RhD blood groups and gestational hypertensive disorders: A population-based cohort study. BJOG 2012; 119: 1232-7.
16. Franchini M, Mengoli C, Lippi G. Relationship between ABO blood group and pregnancy complications: A systematic literature analysis. Blood Transfus 2016; 14: 441-8.
17. Avci D, Karagoz H, Ozer O, Esmeray K, Bulut K, Aykas F, et al. Are the blood groups of women with preeclampsia a risk factor for the development of hypertension postpartum? Ther Clin Risk Manag 2016; 12: 617-22.
18. Manjunatha S, Anita K. The relationship between maternal blood group and preeclampsia. Int J Reprod Contracept Obstet Gynecol 2015; 4: 1749-52.
19. Özkasap S, Dereci S, Sahin K, Dilek AR, Kalyoncuoğlu E, Zengin T. Analysis of ABO and Rh blood groups distribution in East Karadeniz region of Turkey. Dicle Med J 2013; 40: 100-4.
20. Rezk M, Abo-Elnasr M, Al Halaby A, Zahran A, Badr H. Maternal and fetal outcome in women with gestational hypertension in comparison to gestational proteinuria: A 3-year observational study. Hypertens Pregnancy 2016; 35: 181-8.
21. Bilano VL, Ota E, Ganchimeg T, Mori R, Souza JR. Risk factors of pre-eclampsia/ eclampsia and its adverse outcomes in low- and middle-income countries: A WHO secondary analysis. PLoS One 2014; 9: 1-9.
22. Khader YS, Batieha A, Al-njadat RA, Hijazi SS. Preeclampsia in Jordan: Incidence, risk factors, and its associated maternal and neonatal outcomes. J Matern Fetal Neonatal Med 2018; 31: 770-6.

APA	Uzundere O, Kaçar C, andan c, yektaş a (2020). Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. , 53 - 57. 10.4274/imj.galenos.2019.59354
Chicago	Uzundere Osman,Kaçar Cem Kıvılcım,andan cengiz,yektaş abdulkadir Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. (2020): 53 - 57. 10.4274/imj.galenos.2019.59354
MLA	Uzundere Osman,Kaçar Cem Kıvılcım,andan cengiz,yektaş abdulkadir Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. , 2020, ss.53 - 57. 10.4274/imj.galenos.2019.59354
AMA	Uzundere O,Kaçar C,andan c,yektaş a Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. . 2020; 53 - 57. 10.4274/imj.galenos.2019.59354
Vancouver	Uzundere O,Kaçar C,andan c,yektaş a Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. . 2020; 53 - 57. 10.4274/imj.galenos.2019.59354
IEEE	Uzundere O,Kaçar C,andan c,yektaş a "Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?." , ss.53 - 57, 2020. 10.4274/imj.galenos.2019.59354
ISNAD	Uzundere, Osman vd. "Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?". (2020), 53-57. https://doi.org/10.4274/imj.galenos.2019.59354

APA	Uzundere O, Kaçar C, andan c, yektaş a (2020). Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. İstanbul Medical Journal, 21(1), 53 - 57. 10.4274/imj.galenos.2019.59354
Chicago	Uzundere Osman,Kaçar Cem Kıvılcım,andan cengiz,yektaş abdulkadir Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. İstanbul Medical Journal 21, no.1 (2020): 53 - 57. 10.4274/imj.galenos.2019.59354
MLA	Uzundere Osman,Kaçar Cem Kıvılcım,andan cengiz,yektaş abdulkadir Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. İstanbul Medical Journal, vol.21, no.1, 2020, ss.53 - 57. 10.4274/imj.galenos.2019.59354
AMA	Uzundere O,Kaçar C,andan c,yektaş a Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. İstanbul Medical Journal. 2020; 21(1): 53 - 57. 10.4274/imj.galenos.2019.59354
Vancouver	Uzundere O,Kaçar C,andan c,yektaş a Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?. İstanbul Medical Journal. 2020; 21(1): 53 - 57. 10.4274/imj.galenos.2019.59354
IEEE	Uzundere O,Kaçar C,andan c,yektaş a "Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?." İstanbul Medical Journal, 21, ss.53 - 57, 2020. 10.4274/imj.galenos.2019.59354
ISNAD	Uzundere, Osman vd. "Are ABO Blood Groups and Rh Factor Risk Factors for Hypertensive Diseases of Pregnancy?". İstanbul Medical Journal 21/1 (2020), 53-57. https://doi.org/10.4274/imj.galenos.2019.59354