Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder

BARUT, OSMAN; resim, sefa

doi:10.5455/annalsmedres.2019.12.805

Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder

Osman BARUT, (Girilmemişş)

Sefa RESİM (Girilmemişş)

Annals of Medical Research

2 0

Yıl: 2020 Cilt: 27 Sayı: 4 Sayfa Aralığı: 1163 - 1167 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.12.805 İndeks Tarihi: 11-10-2020

Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder

Öz:

AbstractAim: The aim of this study was to evaluate the clinical efficacy and safety of intravesical botulinum neurotoxin-A injection in patients with refractory overactive bladder to conservative treatment and anti-muscarinic drugs.Material and Methods: The data of 62 patients, who received botulinum neurotoxin-A (BonTA) injection (100 U) for overactive bladder (OAB) between 2015 and 2019, were reviewed retrospectively. For 55 patients included into the study, the urinary frequency and urgency, the number of incontinence and nocturia episodes, the maximum flow rate (Qmax), the post-void residual volume (PVR), and the Urinary Incontinence Quality of Life (I-QoL) scores were evaluated before the treatment and at the third month after the treatment.Results: The comparison of the pre-treatment and posttreatment 3rd-month follow-up data revealed a statistically significant decrease in the urinary frequency and urgency, and the number of incontinence and nocturia episodes (p <0.05). There were no statistically significant differences in Qmax and PVR in the posttreatment 3rd month (p> 0.05). The mean I-QoL score increased significantly in the posttreatment 3rd month compared to the pre-treatment scores (43.62 ± 11.2 and 75.2 ± 12.6, p = 0.001, respectively). After the treatment, hematuria developed in 3 female and 2 male patients and urinary tract infections developed in 4 females and 2 male patients.Conclusion: BonTA injection significantly improves the daily urinary frequency, incontinence, and quality of life scores in patients with OAB.

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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	BARUT O, resim s (2020). Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. , 1163 - 1167. 10.5455/annalsmedres.2019.12.805
Chicago	BARUT OSMAN,resim sefa Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. (2020): 1163 - 1167. 10.5455/annalsmedres.2019.12.805
MLA	BARUT OSMAN,resim sefa Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. , 2020, ss.1163 - 1167. 10.5455/annalsmedres.2019.12.805
AMA	BARUT O,resim s Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. . 2020; 1163 - 1167. 10.5455/annalsmedres.2019.12.805
Vancouver	BARUT O,resim s Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. . 2020; 1163 - 1167. 10.5455/annalsmedres.2019.12.805
IEEE	BARUT O,resim s "Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder." , ss.1163 - 1167, 2020. 10.5455/annalsmedres.2019.12.805
ISNAD	BARUT, OSMAN - resim, sefa. "Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder". (2020), 1163-1167. https://doi.org/10.5455/annalsmedres.2019.12.805

APA	BARUT O, resim s (2020). Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. Annals of Medical Research, 27(4), 1163 - 1167. 10.5455/annalsmedres.2019.12.805
Chicago	BARUT OSMAN,resim sefa Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. Annals of Medical Research 27, no.4 (2020): 1163 - 1167. 10.5455/annalsmedres.2019.12.805
MLA	BARUT OSMAN,resim sefa Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. Annals of Medical Research, vol.27, no.4, 2020, ss.1163 - 1167. 10.5455/annalsmedres.2019.12.805
AMA	BARUT O,resim s Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. Annals of Medical Research. 2020; 27(4): 1163 - 1167. 10.5455/annalsmedres.2019.12.805
Vancouver	BARUT O,resim s Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder. Annals of Medical Research. 2020; 27(4): 1163 - 1167. 10.5455/annalsmedres.2019.12.805
IEEE	BARUT O,resim s "Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder." Annals of Medical Research, 27, ss.1163 - 1167, 2020. 10.5455/annalsmedres.2019.12.805
ISNAD	BARUT, OSMAN - resim, sefa. "Botulinum Neurotoxin-A therapy in patients with refractory overactive bladder". Annals of Medical Research 27/4 (2020), 1163-1167. https://doi.org/10.5455/annalsmedres.2019.12.805