Analysis of the association between anxiety and depression levels and oxidative stress levels

Gökçen, Emre; savrun, atakan; EREL, Ozcan; neselioglu, salim; KASKO ARICI, Yeliz; Savrun, Şeyda Tuba; Türkarslan, Murat; Aygun, Ali

doi:10.5455/annalsmedres.2019.12.819

Analysis of the association between anxiety and depression levels and oxidative stress levels

Atakan SAVRUN, (Ordu Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Ordu, Türkiye)

Seyda Tuba SAVRUN, (Ordu Üniversitesi Eğitim ve Araştırma Hastanesi, Acil Tıp Kliniği, Ordu, Türkiye)

ALİ AYGÜN, (Ordu Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Ordu, Türkiye)

Emre Gokcen, (Bozok Üniversitesi, Tıp Fakültesi, Acil Tıp Anabilim Dalı, Yozgat, Türkiye)

Yeliz ARICI, (Ordu Üniversitesi, Tıp Fakültesi, Biyoistatik ve Medikal Bilişim Birimi, Ordu, Türkiye)

Murat TURKARSLAN, (Çankırı Devlet Hastanesi, Acil Tıp Kliniği, Çankırı, Türkiye)

Salim NESELİOGLU, (Yıldırım Beyazıt Üniversitesi, Tıp Fakültesi, Tıbbi Biyokimya Anabilim Dalı, Ankara, Türkiye)

Özcan EREL (Yıldırım Beyazıt Üniversitesi, Tıp Fakültesi, Tıbbi Biyokimya Anabilim Dalı, Ankara, Türkiye)

Annals of Medical Research

2 0

Yıl: 2020 Cilt: 27 Sayı: 4 Sayfa Aralığı: 1193 - 1197 Metin Dili: İngilizce DOI: 10.5455/annalsmedres.2019.12.819 İndeks Tarihi: 11-10-2020

Analysis of the association between anxiety and depression levels and oxidative stress levels

Öz:

AbstractAim: There is a balance between reactive oxygen species (ROS) and antioxidant systems preventing them in the organism. In cases where this balance is impaired, molecular and cellular functions are negatively affected. Thiol-disulfide homeostasis (TDH) is also affected by this imbalance. It has been reported that the balance between oxidative and anti-oxidative systems is disrupted in individuals with psychiatric diseases such as anxiety and depression. Accordingly, it was aimed to determine the level of TDH in the serum of students who took the oral internship exam.Material and Methods: Volunteer fifth grade students of Medical Faculty, 19 male and 21 female, was included in the study. Of the students included in the study, Beck depression and Beck anxiety, albumin, ischemia-modified albumin (IMA), total thiol (SH + SS), native thiol (SH) and SS levels were measured and SS / SH + SS %, SH / SH + SS % and SS / SH % were calculated before and after the oral internship exam. These data were compared with the association between anxiety and depression level changes before and after the oral internship exam.Results: It was observed that the anxiety levels of the participants before the oral exam decreased in the period after the oral exam (p<0.001). It was detected that the level of depression of the participants before the oral exam decreased after the oral exam (p<0.001). Changes in IMA and TDH parameters before and after the oral internship exams were examined, but no significant relationship was found (p>0,05).Conclusion: Oral internship exam of Medical Faculty is a factor increasing anxiety and depression levels of the students. However, no association was found between oral internship exam and TDH parameters.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	savrun a, Savrun Ş, Aygun A, Gökçen E, KASKO ARICI Y, Türkarslan M, neselioglu s, EREL O (2020). Analysis of the association between anxiety and depression levels and oxidative stress levels. , 1193 - 1197. 10.5455/annalsmedres.2019.12.819
Chicago	savrun atakan,Savrun Şeyda Tuba,Aygun Ali,Gökçen Emre,KASKO ARICI Yeliz,Türkarslan Murat,neselioglu salim,EREL Ozcan Analysis of the association between anxiety and depression levels and oxidative stress levels. (2020): 1193 - 1197. 10.5455/annalsmedres.2019.12.819
MLA	savrun atakan,Savrun Şeyda Tuba,Aygun Ali,Gökçen Emre,KASKO ARICI Yeliz,Türkarslan Murat,neselioglu salim,EREL Ozcan Analysis of the association between anxiety and depression levels and oxidative stress levels. , 2020, ss.1193 - 1197. 10.5455/annalsmedres.2019.12.819
AMA	savrun a,Savrun Ş,Aygun A,Gökçen E,KASKO ARICI Y,Türkarslan M,neselioglu s,EREL O Analysis of the association between anxiety and depression levels and oxidative stress levels. . 2020; 1193 - 1197. 10.5455/annalsmedres.2019.12.819
Vancouver	savrun a,Savrun Ş,Aygun A,Gökçen E,KASKO ARICI Y,Türkarslan M,neselioglu s,EREL O Analysis of the association between anxiety and depression levels and oxidative stress levels. . 2020; 1193 - 1197. 10.5455/annalsmedres.2019.12.819
IEEE	savrun a,Savrun Ş,Aygun A,Gökçen E,KASKO ARICI Y,Türkarslan M,neselioglu s,EREL O "Analysis of the association between anxiety and depression levels and oxidative stress levels." , ss.1193 - 1197, 2020. 10.5455/annalsmedres.2019.12.819
ISNAD	savrun, atakan vd. "Analysis of the association between anxiety and depression levels and oxidative stress levels". (2020), 1193-1197. https://doi.org/10.5455/annalsmedres.2019.12.819

APA	savrun a, Savrun Ş, Aygun A, Gökçen E, KASKO ARICI Y, Türkarslan M, neselioglu s, EREL O (2020). Analysis of the association between anxiety and depression levels and oxidative stress levels. Annals of Medical Research, 27(4), 1193 - 1197. 10.5455/annalsmedres.2019.12.819
Chicago	savrun atakan,Savrun Şeyda Tuba,Aygun Ali,Gökçen Emre,KASKO ARICI Yeliz,Türkarslan Murat,neselioglu salim,EREL Ozcan Analysis of the association between anxiety and depression levels and oxidative stress levels. Annals of Medical Research 27, no.4 (2020): 1193 - 1197. 10.5455/annalsmedres.2019.12.819
MLA	savrun atakan,Savrun Şeyda Tuba,Aygun Ali,Gökçen Emre,KASKO ARICI Yeliz,Türkarslan Murat,neselioglu salim,EREL Ozcan Analysis of the association between anxiety and depression levels and oxidative stress levels. Annals of Medical Research, vol.27, no.4, 2020, ss.1193 - 1197. 10.5455/annalsmedres.2019.12.819
AMA	savrun a,Savrun Ş,Aygun A,Gökçen E,KASKO ARICI Y,Türkarslan M,neselioglu s,EREL O Analysis of the association between anxiety and depression levels and oxidative stress levels. Annals of Medical Research. 2020; 27(4): 1193 - 1197. 10.5455/annalsmedres.2019.12.819
Vancouver	savrun a,Savrun Ş,Aygun A,Gökçen E,KASKO ARICI Y,Türkarslan M,neselioglu s,EREL O Analysis of the association between anxiety and depression levels and oxidative stress levels. Annals of Medical Research. 2020; 27(4): 1193 - 1197. 10.5455/annalsmedres.2019.12.819
IEEE	savrun a,Savrun Ş,Aygun A,Gökçen E,KASKO ARICI Y,Türkarslan M,neselioglu s,EREL O "Analysis of the association between anxiety and depression levels and oxidative stress levels." Annals of Medical Research, 27, ss.1193 - 1197, 2020. 10.5455/annalsmedres.2019.12.819
ISNAD	savrun, atakan vd. "Analysis of the association between anxiety and depression levels and oxidative stress levels". Annals of Medical Research 27/4 (2020), 1193-1197. https://doi.org/10.5455/annalsmedres.2019.12.819