Yıl: 2019 Cilt: 20 Sayı: 2 Sayfa Aralığı: 171 - 173 Metin Dili: İngilizce DOI: 10.4274/meandros.galenos.2015.2436 İndeks Tarihi: 29-07-2022

A Rare Cause of Paresthesia: Hypophosphatemia

Öz:
Phosphate is a structural molecule for cells and also is used as coenzyme or as seconder messenger. Renal or gastrointestinal loss of phosphate, diabetes mellitus, chronic alcoholism, hyperparathyroidism, sepsis, increased glucocorticoid, diuretics and antacids may cause hypophosphatemia. Muscle weakness, paresthesia, confusion,convulsion, tremor and coma are neurological symptoms of hypophosphatemia.Main clinical signs occur due to deterioration oxygen distribution and reducedintracellular adenosine triphosphate. In the treatment of hypophosphatemiaidentification of underlying causes is important. In this article, a 26-year-oldyoung male patient with paresthesia that is caused by hypophosphatemia due toD vitamin deficiency is reported. Clinicians must be on the alert about phosphateimbalance which is seen more rare than other electrolytes when investigation ofpatients with paresis and/or paresthesia.
Anahtar Kelime:

Nadir Bir Parestezi Nedeni: Hipofosfatemi

Öz:
Fosfor hücreler için yapısal bir molekül olup ayrıca koenzim ya da ikincil haberci olarak kullanılmaktadır. Fosfatın renal ve gastrointestinal kayıpları, diyabetis mellitus, hiperparatiroidizm, kronik alkolizm, sepsis, glukokortikoid fazlalığı, diüretikler ve antiasitler hipofosfatemiye neden olabilir. Kas güçsüzlüğü, parestezi, konfüzyon, nöbet, tremor ve koma hipofosfateminin nörolojik bulgularındandır. Temel klinik bulgular dokulara oksijen dağılımındaki bozulmaya ve hücre içi adenozin trifosfatın azalmasına bağlı olarak gelişir. Hipofosfateminin tedavisinde altta yatan nedenin belirlenmesi önemlidir. Bu yazıda D vitamini eksikliğine bağlı hipofosfateminin neden olduğu parestezili 26 yaşındaki genç erkek hasta sunulmuştur. Klinisyenler parezi ve/veya parestezili hastaları incelerken diğer elektrolitlere göre daha nadir görülen fosfor bozuklukları hakkında dikkatli olmalıdır.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • Silve C, Friedlander G. Hypo-hyperphosphatemia. In: Davison AM, Cameron CS, Grünfeld JP, Ponticelli C, Ritz E, Winearls CG, Ypersele C, eds. Oxford Textbook of Clinical Nephrology 3nd ed. New York: Oxford University Press; 2005. p.287-99.
  • Emral R. Hipofosfatemik Acil Koşullar. Türkiye Klinikleri J Surg Med Sci 2006; 2: 64-7.
  • Crook M, Swaminathan R. Disorders of plasma phosphate and indications for its measurement. Ann Clin Biochem 1996; 33 : 376-96.
  • Subramanian R, Khardori R. Severe hypophosphatemia. Pathophysiologic implications, clinical presentations, and treatment. Medicine (Baltimore) 2000; 79: 1-8.
  • Háglin L. Hypophosphataemia: cause of the disturbed metabolism in the metabolic syndrome. Med Hypotheses 2001; 56: 657-63.
  • Mohseni M, Chiota N, Roy A, Eidelman B. Severe hypophosphatemia and acute neurologic dysfunction in a marathon runner. Clin J Sport Med 2011; 21: 269-70.
  • Kahvecioğlu S, Hipofosfatemi Tanı ve Tedavisi. Türkiye Klinikleri J Nephrol-Special Topics 2014; 7: 56-9.
APA özözen ayas z, öcal r, BÖLÜK A (2019). A Rare Cause of Paresthesia: Hypophosphatemia. , 171 - 173. 10.4274/meandros.galenos.2015.2436
Chicago özözen ayas zeynep,öcal ruhsen,BÖLÜK Ayhan A Rare Cause of Paresthesia: Hypophosphatemia. (2019): 171 - 173. 10.4274/meandros.galenos.2015.2436
MLA özözen ayas zeynep,öcal ruhsen,BÖLÜK Ayhan A Rare Cause of Paresthesia: Hypophosphatemia. , 2019, ss.171 - 173. 10.4274/meandros.galenos.2015.2436
AMA özözen ayas z,öcal r,BÖLÜK A A Rare Cause of Paresthesia: Hypophosphatemia. . 2019; 171 - 173. 10.4274/meandros.galenos.2015.2436
Vancouver özözen ayas z,öcal r,BÖLÜK A A Rare Cause of Paresthesia: Hypophosphatemia. . 2019; 171 - 173. 10.4274/meandros.galenos.2015.2436
IEEE özözen ayas z,öcal r,BÖLÜK A "A Rare Cause of Paresthesia: Hypophosphatemia." , ss.171 - 173, 2019. 10.4274/meandros.galenos.2015.2436
ISNAD özözen ayas, zeynep vd. "A Rare Cause of Paresthesia: Hypophosphatemia". (2019), 171-173. https://doi.org/10.4274/meandros.galenos.2015.2436
APA özözen ayas z, öcal r, BÖLÜK A (2019). A Rare Cause of Paresthesia: Hypophosphatemia. Meandros Medical And Dental Journal, 20(2), 171 - 173. 10.4274/meandros.galenos.2015.2436
Chicago özözen ayas zeynep,öcal ruhsen,BÖLÜK Ayhan A Rare Cause of Paresthesia: Hypophosphatemia. Meandros Medical And Dental Journal 20, no.2 (2019): 171 - 173. 10.4274/meandros.galenos.2015.2436
MLA özözen ayas zeynep,öcal ruhsen,BÖLÜK Ayhan A Rare Cause of Paresthesia: Hypophosphatemia. Meandros Medical And Dental Journal, vol.20, no.2, 2019, ss.171 - 173. 10.4274/meandros.galenos.2015.2436
AMA özözen ayas z,öcal r,BÖLÜK A A Rare Cause of Paresthesia: Hypophosphatemia. Meandros Medical And Dental Journal. 2019; 20(2): 171 - 173. 10.4274/meandros.galenos.2015.2436
Vancouver özözen ayas z,öcal r,BÖLÜK A A Rare Cause of Paresthesia: Hypophosphatemia. Meandros Medical And Dental Journal. 2019; 20(2): 171 - 173. 10.4274/meandros.galenos.2015.2436
IEEE özözen ayas z,öcal r,BÖLÜK A "A Rare Cause of Paresthesia: Hypophosphatemia." Meandros Medical And Dental Journal, 20, ss.171 - 173, 2019. 10.4274/meandros.galenos.2015.2436
ISNAD özözen ayas, zeynep vd. "A Rare Cause of Paresthesia: Hypophosphatemia". Meandros Medical And Dental Journal 20/2 (2019), 171-173. https://doi.org/10.4274/meandros.galenos.2015.2436