Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination
Yıl: 2020 Cilt: 7 Sayı: 2 Sayfa Aralığı: 83 - 87 Metin Dili: İngilizce DOI: 10.4274/jus.galenos.2019.2916 İndeks Tarihi: 29-07-2022
Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination
Öz: Objective: To reveal the significance of core length in current primary transrectal ultrasound-guided prostate biopsy (TRUS-PB) in patients withnormal digital rectal examination.Materials and Methods: Data of 3520 patients, who received TRUS-PB between March 2002 and April 2015, were reviewed retrospectively. A totalof 1627 primary biopsy patients with a normal digital examination and with no lesion in TRUS were included in the study. The mean core length wasfound by dividing the sum of the total core lengths by the core number. The relationships of cancer detection rate (CDR) with age, Prostate-specificantigen (PSA) value, prostate volume, number of cores (10 or 12 cores) and mean core length were investigated.Results: The mean patient age, PSA and prostate volume were 62.3±7.9 years, 9.1±7.8 ng/mL and 55.8±21 mL, respectively. Cancer was diagnosedin 394 patients (24.2%). The mean core length was 12.7±1.7 (4.3-21.5) mm. Ten- and 12- core biopsies were performed in 1068 (65.6%), and 559(34.4%) patients, respectively. Older age, PSA, mean core length, number of cores and reduced prostate volume were found to be associated withCDR (p<0.001, p<0.001, p=0.006 p=0.043, and p<0.001, respectively). In the multivariate analysis, age, PSA, prostate volume, mean core length, andnumber of cores were found to be independent factors in CDR (p<0.001, p<0.001, p<0.001, p=0.006 and p=0.009, respectively).Conclusion: Age, PSA, prostate volume, and number of cores, together with core length, are independent risk factors for cancer detection in TRUSPB.
Anahtar Kelime: Normal Rektal Muayenesi Olan Hastalarda Transrektal Ultrason Eşliğinde Prostat Biyopsisindeki Kor Uzunluğunun Önemi
Öz: Amaç: Rektal prostat muayenesi normal olan ve Prostat spesifik antijen (PSA) yüksekliği nedeniyle transrektal ultrason eşliğinde iğne biyopsisi (TRUS-BX) yapılan hastalarda kor uzunluğunun prostat kanseri yakalama üzerindeki etkisini araştırmak. Gereç ve Yöntem: Mart 2002 ile Nisan 2015 arasında TRUS-BX yapılan 3520 hastanın verileri retrospektif olarak analiz edildi. Rektal prostat muayenesi normal olan ve TRUS’da lezyonu olan 1627 hasta çalışmaya dahil edildi. Ortalama kor uzunluğu (OKU), toplam kor uzunluğunun alınan kor sayısına bölünmesiyle elde edildi. Yaş, PSA, prostat volümü, ortalama kor uzunluğu ve kor sayısının (10-12 kor) kanser yakalama üzerine etkisi araştırıldı. Bulgular: Ortalama hasta yaşı, PSA ve prostat volümü sırasıyla 62,3±7,9 yıl, 9,1±7,8 ng/mL, 55,8±21 mL idi ve 394 (%24,2) hastada kanser bulundu. Ortalama OKU, 12,7±1,7 (4,3-21,5) mm olarak bulundu. 1068 (%65,6) hastadan 10 kor, 559 (%34,4) hastadan 12 kor biyopsi yapıldığı görüldü. Yüksek yaş, PSA, ortalama kor uzunluğu, kor sayısı ve volümü ile kanser yakalama oranı arasında tek değişkenli analizde anlamlı ilişki bulundu. (p<0,001, p<0,001, p=0,006 p=0,043 ve p<0,001; sırasıyla). Çok değişkenli analizde artan yaş, PSA, ortalama kor uzunluğu, kor sayısı ve azalan prostat volümü kanser yakalamak için bağımsız değişkenler olarak görüldü (p<0,001, p<0,001, p=0,006, p=0,009, p<0,001; sırasıyla). Sonuç: İzole PSA yüksekliği nedeniyle TRUS-BX yapılan hastalarda yaş, PSA, prostat volümü, kor sayısı ile birlikte kor uzunluğu da kanser yakalama oranını bağımsız olarak artırmaktadır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
- Chun FK, Epstein JI, Ficarra V, Freedland SJ, Montironi R, Montorsi F, Shariat SF, Schröder FH, Scattoni V. Optimizing performance and interpretation of prostate biopsy: a critical analysis of the literature. European urology. 2010;58:851-864.
- Boccon-Gibod L, van der Kwast TH, Montironi R, Boccon-Gibod L, Bono A. Handling and pathology reporting of prostate biopsies. European urology. 2004;46:177-181.
- van der Kwast TH, Lopes C, Santonja C, Pihl CG, Neetens I, Martikainen P, Di Lollo S, Bubendorf L, Hoedemaeker RF; Members of the pathology committee of the European Randomised Study of Screening for Prostate Cancer. Guidelines for processing and reporting of prostatic needle biopsies. J Clin Pathol. 2003;56:336-340.
- Guichard G, Larre S, Gallina A, Lazar A, Faucon H, Chemama S, Allory Y, Patard J-J, Vordos D, Hoznek A, Yiou R, Salomon L, Abbou CC, de la Taille A. Extended 21-sample needle biopsy protocol for diagnosis of prostate cancer in 1000 consecutive patients. European urology. 2007;52:430-435.
- Lee S, Jeong SJ, Hwang SI, Hong SK, Lee HJ, Byun SS, Choe G, Lee SE. Clinical value of core length in contemporary multicore prostate biopsy. PloS one. 2015;10:e0123704.
- Shariat SF, Roehrborn CG. Using biopsy to detect prostate cancer. Rev urol. 2008;10:262-280.
- Chang JJ, Shinohara K, Bhargava V, Presti JC, Jr. Prospective evaluation of lateral biopsies of the peripheral zone for prostate cancer detection. The Journal of urology. 1998;160:2111-2114.
- Epstein JI, Walsh PC, Carter HB. Importance of posterolateral needle biopsies in the detection of prostate cancer. Urology. 2001;57:1112-1116.
- Eichler K, Hempel S, Wilby J, Myers L, Bachmann LM, Kleijnen J. Diagnostic value of systematic biopsy methods in the investigation of prostate cancer: a systematic review. J Urol. 2006;175:1605-1612.
- Satoh T, Matsumoto K, Fujita T, Tabata K, Okusa H, Tsuboi T, Arakawa T, Irie A, Egawa S, Baba S. Cancer core distribution in patients diagnosed by extended transperineal prostate biopsy. Urology. 2005;66:114-118.
- Ficarra V, Martignoni G, Novella G, Cerruto MA, Galfano A, Novara G, Pea M, Artibani W. Needle core length is a quality indicator of systematic transperineal prostate biopsy. European urology. 2006;50:266-271.
- Emiliozzi P, Corsetti A, Tassi B, Federico G, Martini M, Pansadoro V. Best approach for prostate cancer detection: a prospective study on transperineal versus transrectal six-core prostate biopsy. Urology. 2003;61:961-966.
- Hara R, Jo Y, Fujii T, Kondo N, Yokoyoma T, Miyaji Y, Nagai A. Optimal approach for prostate cancer detection as initial biopsy: prospective randomized study comparing transperineal versus transrectal systematic 12-core biopsy. Urology. 2008;71:191-195.
- Merrick GS, Irvin S, Fiano R, Anderson R, Butler WM, Adamovich E. Pathology and Quality of Life Outcomes Following Office-based Transperineal Prostate Biopsy. Urology 2016;94:24-28.
- Iczkowski KA, Casella G, Seppala RJ, Jones GL, Mishler BA, Qian J, Bostwick DG. Needle core length in sextant biopsy influences prostate cancer detection rate. Urology. 2002;59:698-703.
- Fiset PO, Aprikian A, Brimo F. Length of prostate biopsy cores: does it impact cancer detection? The Can J Urol. 2013;20:6848-6853.
- Obek C, Doganca T, Erdal S, Erdogan S, Durak H. Core length in prostate biopsy: size matters. J Urol. 2012;187:2051-2055.
- Reis LO, Sanches BC, de Mendonca GB, Silva DM, Aguiar T, Menezes OP, Billis A. Gleason underestimation is predicted by prostate biopsy core length. World J Urol. 2015;33:821-826.
| APA | Altan M, Çıtamak B, mammadov e, Konar N, Akdoğan B, Eliş H (2020). Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. , 83 - 87. 10.4274/jus.galenos.2019.2916 |
| Chicago | Altan Mesut,Çıtamak Burak,mammadov emin,Konar Naime Meric,Akdoğan Bülent,Eliş Haluk Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. (2020): 83 - 87. 10.4274/jus.galenos.2019.2916 |
| MLA | Altan Mesut,Çıtamak Burak,mammadov emin,Konar Naime Meric,Akdoğan Bülent,Eliş Haluk Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. , 2020, ss.83 - 87. 10.4274/jus.galenos.2019.2916 |
| AMA | Altan M,Çıtamak B,mammadov e,Konar N,Akdoğan B,Eliş H Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. . 2020; 83 - 87. 10.4274/jus.galenos.2019.2916 |
| Vancouver | Altan M,Çıtamak B,mammadov e,Konar N,Akdoğan B,Eliş H Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. . 2020; 83 - 87. 10.4274/jus.galenos.2019.2916 |
| IEEE | Altan M,Çıtamak B,mammadov e,Konar N,Akdoğan B,Eliş H "Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination." , ss.83 - 87, 2020. 10.4274/jus.galenos.2019.2916 |
| ISNAD | Altan, Mesut vd. "Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination". (2020), 83-87. https://doi.org/10.4274/jus.galenos.2019.2916 |
| APA | Altan M, Çıtamak B, mammadov e, Konar N, Akdoğan B, Eliş H (2020). Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. Journal of Urological Surgery, 7(2), 83 - 87. 10.4274/jus.galenos.2019.2916 |
| Chicago | Altan Mesut,Çıtamak Burak,mammadov emin,Konar Naime Meric,Akdoğan Bülent,Eliş Haluk Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. Journal of Urological Surgery 7, no.2 (2020): 83 - 87. 10.4274/jus.galenos.2019.2916 |
| MLA | Altan Mesut,Çıtamak Burak,mammadov emin,Konar Naime Meric,Akdoğan Bülent,Eliş Haluk Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. Journal of Urological Surgery, vol.7, no.2, 2020, ss.83 - 87. 10.4274/jus.galenos.2019.2916 |
| AMA | Altan M,Çıtamak B,mammadov e,Konar N,Akdoğan B,Eliş H Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. Journal of Urological Surgery. 2020; 7(2): 83 - 87. 10.4274/jus.galenos.2019.2916 |
| Vancouver | Altan M,Çıtamak B,mammadov e,Konar N,Akdoğan B,Eliş H Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination. Journal of Urological Surgery. 2020; 7(2): 83 - 87. 10.4274/jus.galenos.2019.2916 |
| IEEE | Altan M,Çıtamak B,mammadov e,Konar N,Akdoğan B,Eliş H "Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination." Journal of Urological Surgery, 7, ss.83 - 87, 2020. 10.4274/jus.galenos.2019.2916 |
| ISNAD | Altan, Mesut vd. "Significance of Core Length in Current Transrectal Ultrasound-guided Prostate Biopsy in Patients with Normal Digital Rectal Examination". Journal of Urological Surgery 7/2 (2020), 83-87. https://doi.org/10.4274/jus.galenos.2019.2916 |
