Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females
Yıl: 2020 Cilt: 58 Sayı: 1 Sayfa Aralığı: 110 - 114 Metin Dili: İngilizce DOI: 10.4274/haseki.galenos.2019.5502 İndeks Tarihi: 29-07-2022
Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females
Öz: Aim: Menstrual migraine (MM) is a condition linked to sudden estrogen withdrawal, however, changes in vascular system and neurotransmitters and several hormones are thought to be the underlying causes. Thyroid function affects both menstrual cycle and headache, however, the relationship between thyroid hormones and MM is still not clear. The aim of the study was to evaluate the relationship of MM with thyroid stimulating hormone (TSH), T3, and T4.Methods: Fifty-six patients without MM (group 1), 34 patients with MM (group 2) and 74 controls who had no migraine (group 3) were included in the study. The mean TSH, T3 and T4 levels were compared between the groups. Age, attack frequency (AF), attack period (AP), visual analog scale (VAS) score, Migraine Disability Assessment (MIDAS) grade, and MIDAS score were compared between group 1 and group 2. Correlation analysis was done for TSH, T3, T4 and each of the variables for the groups.Results: The mean T4 level in group 1, group 2 and group 3 was 1.06±1.74, 0.91±0.22 and 1.35±1.19 (p=0.03), respectively. The mean AF was 5.66±6.37 in group 1 and 3.08±1.81 in group 2 (p=0.02).Conclusion: T4 was significantly lower in patients with MM compared to patients without MM, and this difference became more prominent as compared with controls. We would like to draw attention of our colleagues to the relationship between thyroid function (particularly T4 decline) and MM.
Anahtar Kelime: Erişkin Kadınlarda Tiroit Disfonksiyonu ve Menstrüel Migren Arasindaki İlişkinin İncelenmesi
Öz: Amaç: Menstrüel migren (MM) ani östrojen çekilmesine bağlı oluştuğu kabul edilen ancak altta yatan vasküler sistem, nörotransmitterler ve hormonların eşlik ettiği, karmaşık ilişkilere bağlı bir hastalıktır. Tiroit fonksiyonu hem menstrüasyon siklüsü hem de baş ağrısı ile yakın ilişki içerisindedir. Tiroit fonksiyonu ve MM arasındaki ilişki hala kesin olarak aydınlatılamamıştır. Çalışmamız tiroit uyarıcı hormon (TSH), T3, T4 ve MM arasındaki ilişkinin gösterilmesi amacıyla yapılmıştır. Yöntemler: MM olmayan 56 hasta (grup 1), MM olan 34 hasta (grup 2) ve 74 baş ağrısız kontrol (grup 3) dahil edildi. TSH, T3 ve T4 hormonlarının ortalama değerleri gruplar arasında kıyaslandı. Yaş, atak sıklığı (AS), atak süresi (AP), vizüel analog skor (VAS), migren dizabilite ölçeği (MIDAS) evresi ve skoru grup 1 ve grup 2 arasında kıyaslandı. Grup 1 ve grup 2 için, TSH, T3, T4’ün her birinin VAS, MIDAS evresi, MIDAS skoru, AS, AP ile tek tek korelasyon analizi yapıldı. Bulgular: Ortalama T4 seviyesi grup 1’de 1,06±1,74, grup 2’de 0.91±0.22, grup 3’te 1,35±1,19 saptanmıştır (p=0,03). T3 ve TSH seviyeleri gruplar arasında anlamlı fark göstermemekteydi. AS grup 1’de 5,66±6,37, grup 2’de 3,08±1,81 bulundu (p=0,02). Sonuç: T4 seviyesi MM hastalarında MM olmayanlara göre anlamlı düşüktü ve bu düşüklük baş ağrısız kontrollerle kıyaslandığında daha da belirginleşmekteydi. Meslektaşlarımızı MM hastalarında tiroit fonksiyonunun (özellikle de T4 düşüşünün) takip konusunda uyarmak istedik.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | albay v, Tutuncu M (2020). Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. , 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| Chicago | albay vasfiye burcu,Tutuncu Mesude Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. (2020): 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| MLA | albay vasfiye burcu,Tutuncu Mesude Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. , 2020, ss.110 - 114. 10.4274/haseki.galenos.2019.5502 |
| AMA | albay v,Tutuncu M Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. . 2020; 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| Vancouver | albay v,Tutuncu M Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. . 2020; 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| IEEE | albay v,Tutuncu M "Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females." , ss.110 - 114, 2020. 10.4274/haseki.galenos.2019.5502 |
| ISNAD | albay, vasfiye burcu - Tutuncu, Mesude. "Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females". (2020), 110-114. https://doi.org/10.4274/haseki.galenos.2019.5502 |
| APA | albay v, Tutuncu M (2020). Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. Haseki Tıp Bülteni, 58(1), 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| Chicago | albay vasfiye burcu,Tutuncu Mesude Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. Haseki Tıp Bülteni 58, no.1 (2020): 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| MLA | albay vasfiye burcu,Tutuncu Mesude Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. Haseki Tıp Bülteni, vol.58, no.1, 2020, ss.110 - 114. 10.4274/haseki.galenos.2019.5502 |
| AMA | albay v,Tutuncu M Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. Haseki Tıp Bülteni. 2020; 58(1): 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| Vancouver | albay v,Tutuncu M Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females. Haseki Tıp Bülteni. 2020; 58(1): 110 - 114. 10.4274/haseki.galenos.2019.5502 |
| IEEE | albay v,Tutuncu M "Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females." Haseki Tıp Bülteni, 58, ss.110 - 114, 2020. 10.4274/haseki.galenos.2019.5502 |
| ISNAD | albay, vasfiye burcu - Tutuncu, Mesude. "Evaluation of the Relationship Between Thyroid Dysfunction and Menstrual Migraine in Adult Females". Haseki Tıp Bülteni 58/1 (2020), 110-114. https://doi.org/10.4274/haseki.galenos.2019.5502 |
