ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ

GÖZALAN, Ayşegül; ESEN, BERRİN

ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ

Berrin ESEN, (Afyonkarahisar Sağlık Bilimleri Üniveristesi Tıp Fakültesi , Tıbbi Mikrobiyoloji Anabilim Dalı, Afyonkarahisar, TÜRKİYE)

Ayşegül GÖZALAN (Sağlık Bilimleri Üniversitesi Ümraniye SUAM Tıbbi Mikrobiyoloji Kliniği, Bursa, TÜRKİYE.)

Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi

6 0

Yıl: 2020 Cilt: 21 Sayı: 1 Sayfa Aralığı: 211 - 216 Metin Dili: Türkçe İndeks Tarihi: 14-10-2020

ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ

Öz:

Acinetobacter cinsi’nin sınıandırılmasında 12 farklı genomik tür bulunduğu gösterilmiş, taksonomisinde son 30yılda DNA-temelli metotların yaygın kullanımı sayesindedeğişiklikler kaydedilmiştir. Bugün için Acinetobacter cinsi içerisinde 49 tür bulunmaktadır. A. calcoaceticus- A.baumannii complex içinde (ABC) klinik olarak önemli türlerolan A. baumannii (genomik tür 2), Acinetobacter nosocomialis (genomik tür 13TU), Acinetobacter pittii (genomiktür 3) ve Acinetobacter calcoaceticus (genomik tür 1) türleribiyokimyasal olarak ayırd edilemezler. DNA-DNA hibridizasyon, rpoB gen sekans analizi ve multilocus sequencetyping (MLST) ile A. calcoaceticus- A. baumannii complex’eson yıllarda iki yeni patojenik tür olan Acinetobacter seifertiive Acinetobacter djikshoorniae eklenmiştir. Ayrıca non-A.baumannii türleri arasında plazmide lokalize blaNDM-1geni taşıyan ve A. djikshoorniae’nın model suşu olanJVAP01T suşunun taslak genom dizilimi de yayınlanmıştır. Bugün için; Acinetobacter cinsinin tür düzeyinde ayrımı için; RNA polimeraz β-subunit (rpoB) geni, DNA girazB (gyrB) geni sekans analizi ve/veya multilocus sequenceanalysis (MLSA) altın standard moleküler metotlar olarakkabul edilmektedir. Diğer yöntemler; amplified ribosomalDNA restriction analysis (ARDRA), Fourier transform infrared spectroscopy (FTIR) , ve Matriks assisted lazer desorption ionization time of ight mass spectrometry (MALDI-TOFMS)’dur. Acinetobacter türlerine karşı antimikrobiyal dirençgelişimini önlemek için izolatların tür düzeyinde güveniliryöntemler kullanılarak tanımlanmaları, uygun antibiyotiklerin kullanılması ve kesintisiz enfeksiyon kontrol önlemlerinin uygulanması önemlidir.

Anahtar Kelime:

Konular: Mühendislik, Biyotıp Mikrobiyoloji Biyoteknoloji ve Uygulamalı Mikrobiyoloji

ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII (ABC) AND NEW SPECIES

Öz:

The Acinetobacter genus had 12 genomic species. In the last 30 years based on DNA-DNA hybridization the taxonomic di erences has been reported. Currently 49 species are recognized. The biochemically indistinguishable strains, A. baumannii (genomik species 2), Acinetobacter nosocomialis (genomik species 13TU), Acinetobacter pittii (genomik species 3) and Acinetobacter calcoaceticus (genomik species 1) are the clinical important species in the A.calcoaceticus- A.baumannii complex (ABC). Two nowel pathogenic species, Acinetobacter seifertii and Acinetobacter djikshoorniae has been included to A. calcoaceticus- A. baumannii complex by DNA-DNA hybridizaition method, rpoB gene sequence analysis and multilocus sequence typing (MLST) methods. Draft genome sequence of a pathogenic strain JVAP01T, model strain of A. djikshoorniae, which a conjugative plasmid with blaNDM-1 gene has been reported. RNA polimerase β-subunit (rpoB) gene, DNA gyrase B (gyrB) gene sequence analysıs and /or multilocus sequence analysis (MLSA) are known as gold standard molecular methods for the idenitfication at species level. Others are amplified ribosomal DNA restriction analysis (ARDRA), Fourier transform infrared spectroscopy (FTIR) and Matriks assisted lazer desorption ionization time of ight mass spectrometry (MALDI-TOF MS). There is critical importance in keeping the development of antimicrobial resistance of Acinetobacter species at lowest levels such as using relaible laboratory methods, continous infection control measures and rationale antibiotic strategies.

Anahtar Kelime:

Konular: Mühendislik, Biyotıp Mikrobiyoloji Biyoteknoloji ve Uygulamalı Mikrobiyoloji

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık

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APA	ESEN B, GÖZALAN A (2020). ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. , 211 - 216.
Chicago	ESEN BERRİN,GÖZALAN Ayşegül ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. (2020): 211 - 216.
MLA	ESEN BERRİN,GÖZALAN Ayşegül ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. , 2020, ss.211 - 216.
AMA	ESEN B,GÖZALAN A ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. . 2020; 211 - 216.
Vancouver	ESEN B,GÖZALAN A ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. . 2020; 211 - 216.
IEEE	ESEN B,GÖZALAN A "ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ." , ss.211 - 216, 2020.
ISNAD	ESEN, BERRİN - GÖZALAN, Ayşegül. "ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ". (2020), 211-216.

APA	ESEN B, GÖZALAN A (2020). ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi, 21(1), 211 - 216.
Chicago	ESEN BERRİN,GÖZALAN Ayşegül ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi 21, no.1 (2020): 211 - 216.
MLA	ESEN BERRİN,GÖZALAN Ayşegül ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi, vol.21, no.1, 2020, ss.211 - 216.
AMA	ESEN B,GÖZALAN A ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi. 2020; 21(1): 211 - 216.
Vancouver	ESEN B,GÖZALAN A ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ. Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi. 2020; 21(1): 211 - 216.
IEEE	ESEN B,GÖZALAN A "ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ." Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi, 21, ss.211 - 216, 2020.
ISNAD	ESEN, BERRİN - GÖZALAN, Ayşegül. "ACINETOBACTER CALCOACETICUS- ACINETOBACTER BAUMANNII COMPLEX(ABC) VE YENİ TÜRLERİ". Afyon Kocatepe Üniversitesi Kocatepe Tıp Dergisi 21/1 (2020), 211-216.