The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis

Çolakoğlu Er, Hale; YESIL ÇINKIR, HAVVA

doi:doi: 10.5505/tjo.2019.2030

The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis

Havva ÇINKIR, (Gaziantep Üniversitesi, Tıp Fakültesi, Tıbbi Onkoloji Anabilim Dalı, Gaziantep, Türkiye)

Hale ÇOLAKOĞLU ER (Gaziantep Üniversitesi, Tıp Fakültesi Radyoloji Anabilim Dalı, Gaziantep, Türkiye)

Türk Onkoloji Dergisi

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Yıl: 2020 Cilt: 35 Sayı: 2 Sayfa Aralığı: 119 - 126 Metin Dili: İngilizce DOI: doi: 10.5505/tjo.2019.2030 İndeks Tarihi: 17-11-2020

The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis

Öz:

OBJECTIVEBrain metastasis develops in one-third of the patients with adult cancer and it causes significant morbid-ity and mortality on the patients. In this study, we aimed to show the prognostic effects of temporal mus-cle thickness and inflammatory (neutrophil-lymphocyte ratio, platelet-lymphocyte ratio and systemic inflammation response index) and prognostic nutritional index on survival in lung cancer patients with brain metastasis.METHODSIn this study, a total of 94 cancer patients diagnosed with brain metastasis lung cancer were evaluated retrospectively. Routine blood sampling was tested within 10 days of brain MR imaging before the use of steroid therapy.RESULTSTemporal muscle thickness was significantly associated with overall survival, according to cut-off 4.32 (95% CI 0.66-0.99; p=0.040). The risk of death increased by 18.8%, with every millimeter reduction in tem-poral muscle thickness. Neutrophil-lymphocyte ratio, systemic inflammation response index and prog-nostic nutritional index were associated with overall survival (p=0.002, p=0.008, p=0.001, respectively).CONCLUSIONThe findings showed that the use of temporal muscle thickness and inflammatory-nutritional param-eters for the evaluation of sarcopenia were practical and rapid methods. In this group of patients with a short duration of survival, the prognosis of patients can be predicted, and their exposure to toxic treat-ment may be prevented by the evaluation of sarcopenia.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	YESIL ÇINKIR H, Çolakoğlu Er H (2020). The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. , 119 - 126. doi: 10.5505/tjo.2019.2030
Chicago	YESIL ÇINKIR HAVVA,Çolakoğlu Er Hale The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. (2020): 119 - 126. doi: 10.5505/tjo.2019.2030
MLA	YESIL ÇINKIR HAVVA,Çolakoğlu Er Hale The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. , 2020, ss.119 - 126. doi: 10.5505/tjo.2019.2030
AMA	YESIL ÇINKIR H,Çolakoğlu Er H The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. . 2020; 119 - 126. doi: 10.5505/tjo.2019.2030
Vancouver	YESIL ÇINKIR H,Çolakoğlu Er H The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. . 2020; 119 - 126. doi: 10.5505/tjo.2019.2030
IEEE	YESIL ÇINKIR H,Çolakoğlu Er H "The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis." , ss.119 - 126, 2020. doi: 10.5505/tjo.2019.2030
ISNAD	YESIL ÇINKIR, HAVVA - Çolakoğlu Er, Hale. "The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis". (2020), 119-126. https://doi.org/doi: 10.5505/tjo.2019.2030

APA	YESIL ÇINKIR H, Çolakoğlu Er H (2020). The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. Türk Onkoloji Dergisi, 35(2), 119 - 126. doi: 10.5505/tjo.2019.2030
Chicago	YESIL ÇINKIR HAVVA,Çolakoğlu Er Hale The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. Türk Onkoloji Dergisi 35, no.2 (2020): 119 - 126. doi: 10.5505/tjo.2019.2030
MLA	YESIL ÇINKIR HAVVA,Çolakoğlu Er Hale The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. Türk Onkoloji Dergisi, vol.35, no.2, 2020, ss.119 - 126. doi: 10.5505/tjo.2019.2030
AMA	YESIL ÇINKIR H,Çolakoğlu Er H The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. Türk Onkoloji Dergisi. 2020; 35(2): 119 - 126. doi: 10.5505/tjo.2019.2030
Vancouver	YESIL ÇINKIR H,Çolakoğlu Er H The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis. Türk Onkoloji Dergisi. 2020; 35(2): 119 - 126. doi: 10.5505/tjo.2019.2030
IEEE	YESIL ÇINKIR H,Çolakoğlu Er H "The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis." Türk Onkoloji Dergisi, 35, ss.119 - 126, 2020. doi: 10.5505/tjo.2019.2030
ISNAD	YESIL ÇINKIR, HAVVA - Çolakoğlu Er, Hale. "The Prognostic Effects of Temporal Muscle Thickness and Inflammatory-Nutritional Parameters on Survival in Lung Cancer Patients with Brain Metastasis". Türk Onkoloji Dergisi 35/2 (2020), 119-126. https://doi.org/doi: 10.5505/tjo.2019.2030