Objective: This study aimed to examine Turkish validity and reliability of the chemotherapy induced alopecia distress scale. Material and Methods: This study, with a methodological design, was conducted with 101 female breast cancer patients receiving chemotherapy in the outpatient chemotherapy unit of a university hospital, located in Ankara. Patient information form and Turkish version of the chemotherapy induced alopecia distress scale were used to collect data. Language, content and construct validity and reliability coefficients were performed for data analysis. Results: Mean age of the participants was 47.47±9.16. Forty-three point six percent of the patients were diagnosed with stage II breast cancer and most of them received adriamycin, cyclophosphamide chemotherapy regimen (93.1%). There was a high consistency between the expert views on the items of the scale according to content validity index (0.92-1.00). Findings of exploratory factor analysis revealed that Turkish version of the scale included four factor structure and explained 56.8% of the total variance. Cronbach alpha coefficient was calculated as 0.77 for total score of the scale. Conclusion: This study concluded that Turkish version of the chemotherapy induced alopecia distress scale was valid and reliable for the Turkish society. Use of the scale, evaluates impacts of alopecia in a multidimensional aspect, in clinical trials investigating alopecia and its effects on individuals was recommended.