The role of endobronchial ultrasonography elastography for predicting malignancy
Yıl: 2020 Cilt: 28 Sayı: 1 Sayfa Aralığı: 158 - 165 Metin Dili: İngilizce DOI: 10.5606/tgkdc.dergisi.2020.18508 İndeks Tarihi: 11-11-2020
The role of endobronchial ultrasonography elastography for predicting malignancy
Öz: Background: This study aims to investigate the role of endobronchialultrasonography elastography in predicting malignancy.Methods: Between January 2016 and December 2016, a totalof 221 lymph nodes were biopsied using the endobronchialultrasonography-guided transbronchial needle aspiration from119 consecutive patients (69 males, 50 females; mean age63.2±12.4 years; range, 16 to 86 years) were included. Lymphnodes were scored by elastography according to their colors in fourcategories before the procedure. The strain ratio was calculatedbased on the region of interest after three measurements.Results: Of the patients, 93 were diagnosed with a malignancythrough endobronchial ultrasonography-guided transbronchialneedle aspiration biopsy. The mean lymph node score of benignversus malignant lesions was 2.2±1.0 and 3.2±1, respectively(p<0.001). There was a positive correlation between thelymph node scores and lymph node diameter, strain ratio, andfluorodeoxyglucose uptake value (p<0.01). With a cut-off valueof ≥3 of lymph node scoring, the sensitivity for malignancy was79% and specificity was 60%. The mean strain ratio for malignantand benign lymph nodes was 22.2±30.1 and 5.2±1.7, respectively(p<0.001). With a cut-off value of ≥2.47 of strain ratio, thesensitivity for malignancy was 75% and specificity was 65%. Thecombined use of positron emission tomography and lymph nodescore or strain ratio yielded 80.4% and 61.2% sensitivity and 80%and 70.3% specificity for malignancy, respectively.Conclusion: Endobronchial ultrasonography elastography isuseful in predicting malignancy of the lymph nodes. Whencombined with positron emission tomography, specificity andpositive predictive value for malignancy increase.
Anahtar Kelime: Endobronşiyal ultrasonografi elastografinin maligniteyi öngörmedeki rolü
Öz: Amaç: Bu çalışmada endobronşiyal ultrasonografi elastografinin maligniteyi öngörmedeki rolü araştırıldı. Çalışma planı: Ocak 2016 - Aralık 2016 tarihleri arasında, endobronşiyal ultrasonografi eşliğinde transbronşiyal iğne aspirasyon biyopsisi ile 119 ardışık hastadan (69 erkek, 50 kadın; ort. yaş 63.2±12.4 yıl; dağılım 16-86 yıl) toplam 221 lenf nodu çalışmaya alındı. Lenf nodları işlem öncesinde elastografi ile renklerine göre dört kategoride skorlandı. Gerginlik oranı, üç ölçüm sonrasında ilgili bölgeye göre hesaplandı. Bulgular: Hastaların 93’üne endobronşiyal ultrasonografi eşliğinde transbronşiyal iğne aspirasyon biyopsisi ile malignite tanısı konuldu. Benign ve malign lenf nodlarının ortalama skoru sırası ile 2.2±1.0 ve 3.2±1 idi (p<0.001). Lenf nodunun skoru ve lenf nodunun çapı, gerginlik oranı ve florodeoksiglukoz alım değeri arasında pozitif bir ilişki vardı (p<0.01). Lenf nodu skorunun ≥3’lük eşik değeri ile malignite için duyarlılık %79 ve özgüllük %60 idi. Malign ve benign lenf nodlarının ortalama gerginlik oranı sırası ile 22.2±30.1 ve 5.2±1.7 idi (p<0.001). Gerginlik oranının ≥2.47’lik eşik değeri ile malignite duyarlılığı %75 ve özgüllüğü %65 idi. Pozitron emisyon tomografisi ve lenf nodu skoru veya gerginlik oranı birlikte kullanıldığında, malignite duyarlılığı sırası ile %80.4 ve %61.2 ve özgüllüğü %80 ve %70.3 idi. Sonuç: Endobronşiyal ultrasonografi elastografi, lenf nodu malignitelerini öngörmede yararlıdır. Pozitron emisyon tomografisi ile birlikte kullanıldığında, malignite özgüllüğü ve pozitif öngördürücü değeri artar.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Çağlayan B, Iliaz S, BULUTAY P, ARMUTLU A, Uzel F, Ozturk A (2020). The role of endobronchial ultrasonography elastography for predicting malignancy. , 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| Chicago | Çağlayan Benan,Iliaz Sinem,BULUTAY PINAR,ARMUTLU AYŞE,Uzel Fatma Işıl,Ozturk Ayse Bilge The role of endobronchial ultrasonography elastography for predicting malignancy. (2020): 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| MLA | Çağlayan Benan,Iliaz Sinem,BULUTAY PINAR,ARMUTLU AYŞE,Uzel Fatma Işıl,Ozturk Ayse Bilge The role of endobronchial ultrasonography elastography for predicting malignancy. , 2020, ss.158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| AMA | Çağlayan B,Iliaz S,BULUTAY P,ARMUTLU A,Uzel F,Ozturk A The role of endobronchial ultrasonography elastography for predicting malignancy. . 2020; 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| Vancouver | Çağlayan B,Iliaz S,BULUTAY P,ARMUTLU A,Uzel F,Ozturk A The role of endobronchial ultrasonography elastography for predicting malignancy. . 2020; 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| IEEE | Çağlayan B,Iliaz S,BULUTAY P,ARMUTLU A,Uzel F,Ozturk A "The role of endobronchial ultrasonography elastography for predicting malignancy." , ss.158 - 165, 2020. 10.5606/tgkdc.dergisi.2020.18508 |
| ISNAD | Çağlayan, Benan vd. "The role of endobronchial ultrasonography elastography for predicting malignancy". (2020), 158-165. https://doi.org/10.5606/tgkdc.dergisi.2020.18508 |
| APA | Çağlayan B, Iliaz S, BULUTAY P, ARMUTLU A, Uzel F, Ozturk A (2020). The role of endobronchial ultrasonography elastography for predicting malignancy. Türk Göğüs Kalp Damar Cerrahisi Dergisi, 28(1), 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| Chicago | Çağlayan Benan,Iliaz Sinem,BULUTAY PINAR,ARMUTLU AYŞE,Uzel Fatma Işıl,Ozturk Ayse Bilge The role of endobronchial ultrasonography elastography for predicting malignancy. Türk Göğüs Kalp Damar Cerrahisi Dergisi 28, no.1 (2020): 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| MLA | Çağlayan Benan,Iliaz Sinem,BULUTAY PINAR,ARMUTLU AYŞE,Uzel Fatma Işıl,Ozturk Ayse Bilge The role of endobronchial ultrasonography elastography for predicting malignancy. Türk Göğüs Kalp Damar Cerrahisi Dergisi, vol.28, no.1, 2020, ss.158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| AMA | Çağlayan B,Iliaz S,BULUTAY P,ARMUTLU A,Uzel F,Ozturk A The role of endobronchial ultrasonography elastography for predicting malignancy. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2020; 28(1): 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| Vancouver | Çağlayan B,Iliaz S,BULUTAY P,ARMUTLU A,Uzel F,Ozturk A The role of endobronchial ultrasonography elastography for predicting malignancy. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2020; 28(1): 158 - 165. 10.5606/tgkdc.dergisi.2020.18508 |
| IEEE | Çağlayan B,Iliaz S,BULUTAY P,ARMUTLU A,Uzel F,Ozturk A "The role of endobronchial ultrasonography elastography for predicting malignancy." Türk Göğüs Kalp Damar Cerrahisi Dergisi, 28, ss.158 - 165, 2020. 10.5606/tgkdc.dergisi.2020.18508 |
| ISNAD | Çağlayan, Benan vd. "The role of endobronchial ultrasonography elastography for predicting malignancy". Türk Göğüs Kalp Damar Cerrahisi Dergisi 28/1 (2020), 158-165. https://doi.org/10.5606/tgkdc.dergisi.2020.18508 |
