Yıl: 2019 Cilt: 3 Sayı: 3 Sayfa Aralığı: 254 - 260 Metin Dili: İngilizce DOI: 10.30565/medalanya.543371 İndeks Tarihi: 15-11-2020

Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections

Öz:
Aim: Acinetobacter baumannii is an important nosocomial pathogen. The purpose ofthis study was to identify risk factors and mortality of nosocomial infections causedby pan drug resistant (PDR) Acinetobacter baumannii and to characterize theireffects on mortality.Patients and Methods: This study was performed at the Afyon Kocatepe UniversityFaculty of Medicine. Nosocomial infections were defined according to the AmericanCenter for Disease Control (CDC). Patients with nosocomial infections caused byAcinetobacter baumannii were included in the study. Patients identified as PDRAcinetobacter baumannii and non-PDR Acinetobacter baumannii infection were compared in terms of risk factors.Results: Two different groups were constructed, one group consisting of 145 PDRand the other of 145 non-PDR Acinetobacter baumannii cases. Stay history in aninternal intensive care unit (p=0.001), their duration of hospital stay (p=0.031), renaldisease (p=0.003), mechanical ventilation (p=0.001), prior usage history of carbapenem (p=0.001), presence of nosocomial pneumonia (p=0.001), were independentrisk factors associated with PDR Acinetobacter baumannii infections. The mortalityrate for the PDR group was 61.8% and it was 38.2% in the non-PDR group (p=0.008).Conclusion: PDR Acinetobacter baumannii infections are important nosocomial infections with a high mortality rate. Patients’ carbapenem usage, stay history in aninternal intensive care unit, renal comorbid diseases, and a diagnosis of nosocomialpneumonia are important risk factors for PDR Acinetobacter baumannii infections. Innosocomial infections caused by PDR Acinetobacter baumannii, many risk factorswere modifiable.
Anahtar Kelime:

Hastane Kaynaklı Pan Drug Resistant Acinetobacter Baumannii Enfeksiyonlarında Risk Faktörleri

Öz:
Amaç: Acinetobacter baumannii, önemli nozokomiyal bir patojendir. Bu çalışmanın amacı, pan drug resistant (PDR) Acinetobacter baumannii nedenli nosokomiyal enfeksiyonlar için risk faktörlerinin ve mortalite üzerine olan etkinin tanımlanmasıdır. Hastalar ve Yöntemler: Çalışma Afyon Kocatepe Üniversitesi Tıp Fakültesi’nde gerçekleştirilmiştir. Amerikan Hastalık Kontrol Merkezi (CDC) tanı kriterlerine göre tanımlanmıştır. Acinetobacter baumannii nedenli nozokomiyal enfeksiyon tanımlanan hastalar çalışmaya dahil edilmiştir. PDR Acinetobacter baumannii ve non-PDR Acinetobacter baumannii enfeksiyonu saptanan olgular risk faktörleri yönünden karşılaştırılmıştır Bulgular: Biri 145 PDR diğeri 145 PDR olmayan Acinetobacter baumannii vakalarından oluşan iki farklı grup oluşturuldu. Dahili yoğun bakım ünitesinde yatış öyküsü (p=0,001), hastanede kalış süresi PDR grupta ortalama 28,2±23,0 (p=0,031), renal hastalık (p=0,003), mekanik ventilasyon (p=0,001),önceden karbapenem kullanma öyküsü (p=0,001), nozokomiyal pnömoni varlığı, (p=0,001 bağımsız risk faktörü olmuştur. Mortalite oranı PDR grupta % 61,8, non-PDR grupta % 38,2, olarak belirlenmiştir (p=0,008). Sonuç: PDR Acinetobacter baumannii enfeksiyonları mortalite oranı yüksek önemli nozokomiyal infeksiyonlardır. Dahili yoğun bakım ünitesinde yatış öyküsü, hastanede kalış süresi, renal hastalık, mekanik ventilasyon, karbapenem kulanım öyküsü, nozokomiyal pnömoni varlığı, solunum sekresyon örneği PDR Acinetobacter baumannii enfeksiyonu için önemli risk faktörleridir. PDR Acinetobacter baumannii nedenli nozokomiyal enfeksiyonlarda çoğu risk faktörleri düzeltilebilir özelliktedir.
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APA TUNAY H, DEMİRDAL T, Demirturk N (2019). Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. , 254 - 260. 10.30565/medalanya.543371
Chicago TUNAY Havva,DEMİRDAL Tuna,Demirturk Nese Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. (2019): 254 - 260. 10.30565/medalanya.543371
MLA TUNAY Havva,DEMİRDAL Tuna,Demirturk Nese Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. , 2019, ss.254 - 260. 10.30565/medalanya.543371
AMA TUNAY H,DEMİRDAL T,Demirturk N Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. . 2019; 254 - 260. 10.30565/medalanya.543371
Vancouver TUNAY H,DEMİRDAL T,Demirturk N Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. . 2019; 254 - 260. 10.30565/medalanya.543371
IEEE TUNAY H,DEMİRDAL T,Demirturk N "Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections." , ss.254 - 260, 2019. 10.30565/medalanya.543371
ISNAD TUNAY, Havva vd. "Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections". (2019), 254-260. https://doi.org/10.30565/medalanya.543371
APA TUNAY H, DEMİRDAL T, Demirturk N (2019). Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. Acta Medica Alanya, 3(3), 254 - 260. 10.30565/medalanya.543371
Chicago TUNAY Havva,DEMİRDAL Tuna,Demirturk Nese Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. Acta Medica Alanya 3, no.3 (2019): 254 - 260. 10.30565/medalanya.543371
MLA TUNAY Havva,DEMİRDAL Tuna,Demirturk Nese Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. Acta Medica Alanya, vol.3, no.3, 2019, ss.254 - 260. 10.30565/medalanya.543371
AMA TUNAY H,DEMİRDAL T,Demirturk N Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. Acta Medica Alanya. 2019; 3(3): 254 - 260. 10.30565/medalanya.543371
Vancouver TUNAY H,DEMİRDAL T,Demirturk N Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections. Acta Medica Alanya. 2019; 3(3): 254 - 260. 10.30565/medalanya.543371
IEEE TUNAY H,DEMİRDAL T,Demirturk N "Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections." Acta Medica Alanya, 3, ss.254 - 260, 2019. 10.30565/medalanya.543371
ISNAD TUNAY, Havva vd. "Risk Factors For Nosocomial Pan Drug Resistant Acinetobacter Baumannii Infections". Acta Medica Alanya 3/3 (2019), 254-260. https://doi.org/10.30565/medalanya.543371