The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems
Yıl: 2020 Cilt: 40 Sayı: 3 Sayfa Aralığı: 358 - 365 Metin Dili: İngilizce DOI: 10.5336/medsci.2020-74753 İndeks Tarihi: 20-11-2020
The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems
Öz: Objective: To investigate the treatment indications andcompliance of individuals who underwent preventive treatment for latent tuberculosis infection (LTBI) in Turkey at the provincial level. Material and Methods: The data were collected retrospectively fromrecords of 1,147 tuberculosis (TB) patients who have been followed-upin Elazığ TB Dispensary between the years 2005 and 2013. Results:Preventive treatment of LTBI was applied to 1,264 registered individuals for the indication of various factors. The causative factors for initiating preventive therapy were the history of contact with TB patients(55.1%), immunosuppression (28.2%), tuberculin skin test (TST) positivity (8.2%), TST conversion (0.1%) and for other reasons (8.4%). Ofthe patients, 66.3% had completed preventive treatment with success,however, 33.4% have abandoned their therapies. All of the patientshave used isoniazid as preventive drug treatment. Conclusion: Preventive treatment for LTBI was applied most frequently with the indication of contact history with TB and the second indication wasimmunocompromised patients either by getting the drug or having adisease that is susceptible to TB infection. Unfortunately, the results ofthe study suggested that rates of completed treatment were not highenough.
Anahtar Kelime: Latent Tüberküloz Enfeksiyonu Tedavisi: İl Bazlı Uygulamalar ve Sorunlar
Öz: Amaç: Türkiye'de latent tüberküloz enfeksiyonu (LTE) için önleyici tedavi gören bireylerin il düzeyinde tedavi endikasyonlarını ve uyumlarını araştırmak. Gereç ve Yöntemler: Elazığ Verem Savaşı Dispanseri’nde 2005-2013 yılları arasında kayıtlı koruyucu ilaç tedavisi alanlara ait veriler dosyalardan kaydedilmiştir. Bulgular: LTE için koruyucu tedavi, farklı endikasyonlarda 1.264 kişiye uygulanmıştır. Koruyucu tedavi alan bireylerin %55,1’ine tüberküloz hastası ile temas öyküsü, %28,2’sine (n=357) bağışıklığın baskılanması, %8,2’sine tüberkülin deri testi (TDT) pozitifliği, %0,1’ine TDT konversiyonu, %8,4’üne ise diğer nedenlerle koruyucu ilaç tedavisi başlanmıştır. Koruyucu tedavi alan bireylerin %66,3’ünün tedavileri tamamlanmış, %33,4’ü ise koruyucu ilaç tedavisini terk etmiştir. Koruyucu ilaç tedavisinde bireylerin tamamı izoniyazid kullanmıştır. Sonuç: Koruyucu ilaç tedavisi alan bireylerin çoğunluğunu tüberküloz hastası ile temas öyküsü olanlar oluştururken; ikinci sırada ise gerek ilaç kullanımı gerekse bir hastalık nedeni ile tüberküloza yatkınlık gösteren bağışıklığı baskılanmış bireyler yer almaktadır. Çalışmamızın sonuçlarına göre tedaviyi tamamlama oranları yeterince yüksek değildir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Türkkanı M, Ozdilekcan C, ÖZDEMİR T, Kucuk C, akkuş i (2020). The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. , 358 - 365. 10.5336/medsci.2020-74753 |
| Chicago | Türkkanı Mustafa Hamidullah,Ozdilekcan Cigdem,ÖZDEMİR TARKAN,Kucuk Canan,akkuş ibrahim halil The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. (2020): 358 - 365. 10.5336/medsci.2020-74753 |
| MLA | Türkkanı Mustafa Hamidullah,Ozdilekcan Cigdem,ÖZDEMİR TARKAN,Kucuk Canan,akkuş ibrahim halil The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. , 2020, ss.358 - 365. 10.5336/medsci.2020-74753 |
| AMA | Türkkanı M,Ozdilekcan C,ÖZDEMİR T,Kucuk C,akkuş i The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. . 2020; 358 - 365. 10.5336/medsci.2020-74753 |
| Vancouver | Türkkanı M,Ozdilekcan C,ÖZDEMİR T,Kucuk C,akkuş i The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. . 2020; 358 - 365. 10.5336/medsci.2020-74753 |
| IEEE | Türkkanı M,Ozdilekcan C,ÖZDEMİR T,Kucuk C,akkuş i "The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems." , ss.358 - 365, 2020. 10.5336/medsci.2020-74753 |
| ISNAD | Türkkanı, Mustafa Hamidullah vd. "The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems". (2020), 358-365. https://doi.org/10.5336/medsci.2020-74753 |
| APA | Türkkanı M, Ozdilekcan C, ÖZDEMİR T, Kucuk C, akkuş i (2020). The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. Türkiye Klinikleri Tıp Bilimleri Dergisi, 40(3), 358 - 365. 10.5336/medsci.2020-74753 |
| Chicago | Türkkanı Mustafa Hamidullah,Ozdilekcan Cigdem,ÖZDEMİR TARKAN,Kucuk Canan,akkuş ibrahim halil The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. Türkiye Klinikleri Tıp Bilimleri Dergisi 40, no.3 (2020): 358 - 365. 10.5336/medsci.2020-74753 |
| MLA | Türkkanı Mustafa Hamidullah,Ozdilekcan Cigdem,ÖZDEMİR TARKAN,Kucuk Canan,akkuş ibrahim halil The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. Türkiye Klinikleri Tıp Bilimleri Dergisi, vol.40, no.3, 2020, ss.358 - 365. 10.5336/medsci.2020-74753 |
| AMA | Türkkanı M,Ozdilekcan C,ÖZDEMİR T,Kucuk C,akkuş i The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. Türkiye Klinikleri Tıp Bilimleri Dergisi. 2020; 40(3): 358 - 365. 10.5336/medsci.2020-74753 |
| Vancouver | Türkkanı M,Ozdilekcan C,ÖZDEMİR T,Kucuk C,akkuş i The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems. Türkiye Klinikleri Tıp Bilimleri Dergisi. 2020; 40(3): 358 - 365. 10.5336/medsci.2020-74753 |
| IEEE | Türkkanı M,Ozdilekcan C,ÖZDEMİR T,Kucuk C,akkuş i "The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems." Türkiye Klinikleri Tıp Bilimleri Dergisi, 40, ss.358 - 365, 2020. 10.5336/medsci.2020-74753 |
| ISNAD | Türkkanı, Mustafa Hamidullah vd. "The Treatment of Latent Tuberculosis Infection: Province Based Practice and Problems". Türkiye Klinikleri Tıp Bilimleri Dergisi 40/3 (2020), 358-365. https://doi.org/10.5336/medsci.2020-74753 |
