Yıl: 2020 Cilt: 26 Sayı: 3 Sayfa Aralığı: 202 - 207 Metin Dili: İngilizce DOI: 10.5152/eurjther.2020.19047 İndeks Tarihi: 22-11-2020

Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats

Öz:
Objective: This study aimed to investigate the radioprotective effects of propolis and caffeic acid phenethyl ester (CAPE) againstradiation-induced damage in the tongue-tissues of rats exposed to total cranial gamma irradiation.Methods: Fifty-four Sprague-Dawley rats were randomly divided into six groups. An appropriate control group was also studied.The animals were euthanized on day 10, and tongue-tissues were collected for evaluating biochemical oxidative parameters.Results: Lipid hydroperoxides (LOOH), total oxidant status (TOS), oxidative stress index (OSI) levels and xanthine oxidase (XO) activity, and markers of oxidative stress were significantly higher, while paraoxonase (PON) activity was significantly lower for irradiatedrats (IR) group compared to the other groups. When LOOH, TOS, OSI values, and XO activity in the propolis+IR and CAPE+IR groupswere evaluated, there was no statistically significant difference between those ones and all control groups. In terms of the total-SH levels, the propolis+IR group was found to be significantly higher than all other groups. There was no significant difference inarylesterase (ARE) activity, ceruloplasmin (Cp) levels.Conclusion: Propolis and CAPE reduce oxidative stress and have antioxidant effects that may be useful agents of ionizing radiation-induced tissue damage
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APA Altay H, Demir E, Binici H, Aytac I, TAYSI M, Taysı S (2020). Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. , 202 - 207. 10.5152/eurjther.2020.19047
Chicago Altay Halis,Demir Elif,Binici Habip,Aytac Ismail,TAYSI Muhammed Enes,Taysı Seyithan Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. (2020): 202 - 207. 10.5152/eurjther.2020.19047
MLA Altay Halis,Demir Elif,Binici Habip,Aytac Ismail,TAYSI Muhammed Enes,Taysı Seyithan Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. , 2020, ss.202 - 207. 10.5152/eurjther.2020.19047
AMA Altay H,Demir E,Binici H,Aytac I,TAYSI M,Taysı S Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. . 2020; 202 - 207. 10.5152/eurjther.2020.19047
Vancouver Altay H,Demir E,Binici H,Aytac I,TAYSI M,Taysı S Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. . 2020; 202 - 207. 10.5152/eurjther.2020.19047
IEEE Altay H,Demir E,Binici H,Aytac I,TAYSI M,Taysı S "Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats." , ss.202 - 207, 2020. 10.5152/eurjther.2020.19047
ISNAD Altay, Halis vd. "Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats". (2020), 202-207. https://doi.org/10.5152/eurjther.2020.19047
APA Altay H, Demir E, Binici H, Aytac I, TAYSI M, Taysı S (2020). Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. European Journal of Therapeutics, 26(3), 202 - 207. 10.5152/eurjther.2020.19047
Chicago Altay Halis,Demir Elif,Binici Habip,Aytac Ismail,TAYSI Muhammed Enes,Taysı Seyithan Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. European Journal of Therapeutics 26, no.3 (2020): 202 - 207. 10.5152/eurjther.2020.19047
MLA Altay Halis,Demir Elif,Binici Habip,Aytac Ismail,TAYSI Muhammed Enes,Taysı Seyithan Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. European Journal of Therapeutics, vol.26, no.3, 2020, ss.202 - 207. 10.5152/eurjther.2020.19047
AMA Altay H,Demir E,Binici H,Aytac I,TAYSI M,Taysı S Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. European Journal of Therapeutics. 2020; 26(3): 202 - 207. 10.5152/eurjther.2020.19047
Vancouver Altay H,Demir E,Binici H,Aytac I,TAYSI M,Taysı S Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats. European Journal of Therapeutics. 2020; 26(3): 202 - 207. 10.5152/eurjther.2020.19047
IEEE Altay H,Demir E,Binici H,Aytac I,TAYSI M,Taysı S "Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats." European Journal of Therapeutics, 26, ss.202 - 207, 2020. 10.5152/eurjther.2020.19047
ISNAD Altay, Halis vd. "Radioprotective Effects of Propolis and Caffeic acid phenethyl ester on the Tongue-Tissues of Total-Head Irradiated Rats". European Journal of Therapeutics 26/3 (2020), 202-207. https://doi.org/10.5152/eurjther.2020.19047