Objective: The Special Study Modules (SSM) have been integrated into Dokuz Eylül University Medical School's educational activities for the first three years. In 2017-2018 academic year, four second-year students of Dokuz Eylül University Medical School participated in our SSM study, which was in the laboratory research category. The aim of this study was to investigate the possible effect of alpha lipoic acid on p38 MAPK signalling pathway in cisplatin-induced testicular damage, as well as to provide students with the skills of independent learning, knowledge on the basic principles of scientific methodology and with the ability to present scientific research results both orally and in writing. Material and Method: In SSM, Wistar albino rats were divided into three groups: Control group (n=7), cisplatin (16 mg/kg, intraperitoneal, ip) (damage group) (n=7) and cisplatin+alpha lipoic acid (LA) (100 mg/kg, ip) (treatment group). Total p38 MAPK and phosphorylated p38 (p-p38) signalling pathway protein expression in testicular tissues were evaluated by western blot method and cellular localization was assessed through immunohistochemistry. After the experimental analyses, the students prepared a written report and presented the outcomes orally at the end of the academic year. They assessed the SSM process through the feedback they gave at the end of the term. Findings: At the end of the special study, students gained experience in the literature review, scientific research planning, applying to an ethics committee, basic laboratory techniques and evaluating the findings of the analysis. Besides, the students stated that they learned to read and discuss scientific articles and were satisfied with the laboratory and the research skills they acquired. When the experimental findings were evaluated, it was ascertained that total p38 and p-p38 protein expressions in the cisplatin-induced damage group increased significantly compared to those in the control group (p <0.05). However, this increase lessened significantly when LA was administered (p <0.05). The immunohistochemical findings were similar to western blot results in terms of the distribution detected within the seminiferous tubules. Conclusion: This SSM, aiming at improving independent learning skills of the students and enabling them to learn the basic principles of scientific methodology, will be a guide for the formation of new SSMs within the curriculum of the Medical School.