Nontyphoidal salmonella (NTS) infection can lead to gastroenteritis, enteric fever, and bacteremia. However, osteoarticular infections caused by NTS are rarely encountered. We report the case of a 53-year-old male patient with bilateral hip infection causedby NTS. We performed a two-stage reconstruction comprising debridement of both hip joints followed by prosthetic replacementwith antibiotic-loaded acrylic cement because the patient’s diagnosis was delayed for approximately three months and the hipjoints were already damaged. At two-year follow-up, the clinical, radiologic, and laboratory findings were within the normal limits,and there was no sign of infection. This case is presented because reports of bilateral hip joint infection due to NTS are rare. Earlydetection and proper treatment are essential for the eradication of the infection. The use of a prosthesis made of antibiotic-loadedacrylic cement and prolonged antimicrobial therapy can be considered in the management of bilateral hip joint destruction due todelayed diagnosis of NTS infection.