The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study

hancı, fatma; CANPOLAT, MEHMET; PER, Hüseyin; GÜMÜŞ, HAKAN; KUMANDAS, Sefer

doi:10.30714/j-ebr.2019250351

The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study

Fatma HANCI, (Bolu Abant İzzet Baysal Üniversitesi, Tıp Fakültesi, Çocuk Nörolojisi Bilim Dalı, Bolu, Türkiye)

Mehmet CANPOLAT, (Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Nörolojisi Bilim Dalı, Kayseri, Türkiye)

Hüseyin PER, (Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Nörolojisi Bilim Dalı, Kayseri, Türkiye)

Hakan GÜMÜŞ, (Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Nörolojisi Bilim Dalı, Kayseri, Türkiye)

Sefer KUMANDAS (Erciyes Üniversitesi, Tıp Fakültesi, Çocuk Nörolojisi Bilim Dalı, Kayseri, Türkiye)

Experimental Biomedical Research

5 0

Yıl: 2019 Cilt: 2 Sayı: 2 Sayfa Aralığı: 62 - 68 Metin Dili: İngilizce DOI: 10.30714/j-ebr.2019250351 İndeks Tarihi: 28-10-2020

The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study

Öz:

Aim: This study investigated the effect of antiepileptic drug monotherapy on cognitive functions inpediatric epilepsy patients.Methods: 98 recently diagnosed epilepsy patients aged 6-16 years were included. All patientsunderwent routine laboratory tests, electroencephalography, brain magnetic resonance imaging, andintelligence testing. The patients were treated with valproic acid (VA), carbamazepine (CBZ),oxcarbazepine (OXC), or levetiracetam (LEV). The Wechsler Intelligence Scale for Children (WISCR) was applied three times, before, six months and 12 months after the start of antiepileptic therapy.Results: No significant difference was determined among the mean verbal, performance and totalintelligence scores of patients using a single antiepileptic drug at baseline, after six or 12 months.Conclusion: We conclude that the type of antiepileptic drug using has no adverse effects on cognitivefunctions.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	hancı f, CANPOLAT M, PER H, GÜMÜŞ H, KUMANDAS S (2019). The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. , 62 - 68. 10.30714/j-ebr.2019250351
Chicago	hancı fatma,CANPOLAT MEHMET,PER Hüseyin,GÜMÜŞ HAKAN,KUMANDAS Sefer The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. (2019): 62 - 68. 10.30714/j-ebr.2019250351
MLA	hancı fatma,CANPOLAT MEHMET,PER Hüseyin,GÜMÜŞ HAKAN,KUMANDAS Sefer The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. , 2019, ss.62 - 68. 10.30714/j-ebr.2019250351
AMA	hancı f,CANPOLAT M,PER H,GÜMÜŞ H,KUMANDAS S The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. . 2019; 62 - 68. 10.30714/j-ebr.2019250351
Vancouver	hancı f,CANPOLAT M,PER H,GÜMÜŞ H,KUMANDAS S The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. . 2019; 62 - 68. 10.30714/j-ebr.2019250351
IEEE	hancı f,CANPOLAT M,PER H,GÜMÜŞ H,KUMANDAS S "The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study." , ss.62 - 68, 2019. 10.30714/j-ebr.2019250351
ISNAD	hancı, fatma vd. "The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study". (2019), 62-68. https://doi.org/10.30714/j-ebr.2019250351

APA	hancı f, CANPOLAT M, PER H, GÜMÜŞ H, KUMANDAS S (2019). The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. Experimental Biomedical Research, 2(2), 62 - 68. 10.30714/j-ebr.2019250351
Chicago	hancı fatma,CANPOLAT MEHMET,PER Hüseyin,GÜMÜŞ HAKAN,KUMANDAS Sefer The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. Experimental Biomedical Research 2, no.2 (2019): 62 - 68. 10.30714/j-ebr.2019250351
MLA	hancı fatma,CANPOLAT MEHMET,PER Hüseyin,GÜMÜŞ HAKAN,KUMANDAS Sefer The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. Experimental Biomedical Research, vol.2, no.2, 2019, ss.62 - 68. 10.30714/j-ebr.2019250351
AMA	hancı f,CANPOLAT M,PER H,GÜMÜŞ H,KUMANDAS S The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. Experimental Biomedical Research. 2019; 2(2): 62 - 68. 10.30714/j-ebr.2019250351
Vancouver	hancı f,CANPOLAT M,PER H,GÜMÜŞ H,KUMANDAS S The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study. Experimental Biomedical Research. 2019; 2(2): 62 - 68. 10.30714/j-ebr.2019250351
IEEE	hancı f,CANPOLAT M,PER H,GÜMÜŞ H,KUMANDAS S "The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study." Experimental Biomedical Research, 2, ss.62 - 68, 2019. 10.30714/j-ebr.2019250351
ISNAD	hancı, fatma vd. "The relation between antiepileptic drug type and cognitive functions in childhood epilepsy: A prospective observational study". Experimental Biomedical Research 2/2 (2019), 62-68. https://doi.org/10.30714/j-ebr.2019250351