Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center

AKCA, Baris; COLAK, Mehmet Cengiz; Battaloglu, Bektas; erdil, nevzat; disli, olcay murat

Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center

Baris AKCA, (İnönü Üniversitesi, Tıp Fakültesi, kardiyovasküler Cerrahi Anabilim Dalı, Malatya, Türkiye .)

Nevzat ERDİL, (İnönü Üniversitesi, Tıp Fakültesi, kardiyovasküler Cerrahi Anabilim Dalı, Malatya, Türkiye .)

Mehmet Cengiz COLAK, (İnönü Üniversitesi, Tıp Fakültesi, kardiyovasküler Cerrahi Anabilim Dalı, Malatya, Türkiye .)

Olcay Murat DİSLİ, (İnönü Üniversitesi, Tıp Fakültesi, kardiyovasküler Cerrahi Anabilim Dalı, Malatya, Türkiye .)

Bektas BATTALOGLU (İnönü Üniversitesi, Tıp Fakültesi, kardiyovasküler Cerrahi Anabilim Dalı, Malatya, Türkiye .)

Medicine Science

4 1

Yıl: 2020 Cilt: 9 Sayı: 1 Sayfa Aralığı: 9 - 15 Metin Dili: İngilizce İndeks Tarihi: 29-10-2020

Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center

Öz:

Infective endocarditis (IE) is still associated with severe complications and poor prognosis. The surgery of IE has various technical difficulties due to severe infection, inflammation of heart tissue, and systemic effects, so controversies continue about the optimal timing of operation. This study presents the treatment approaches, early and late-term outcomes of IE patients, who underwent surgery.This retrospective descriptive study is conducted with 46 patients (31males) operated between 2002-2018. The demographics and preoperative, intraoperative and postoperative data of patients were analyzed from the clinical database and patient records. Emergency surgery was performed to 15 (32.26%) patients.Numbers of patients with mitral valve, aortic valve, and prosthetic valve endocarditis were 14, 25, 7 respectively. Aortic valve replacement (AVR), mitral valve replacement (MVR), MVR + AVR and mitral valve repair were performed in 24, 12, 8 and 2 patients, respectively. Additionally, peri-cardial patch repair (periannular abscess or damage (n=12), aorta-right atrial fistulae (n=3)), debulking of associated tricuspid valve vegetation (n=2), tricuspid De Vega annuloplasty (n=3), Bentall operation (n=1) and aortic root enlargement (n=5) were performed. The mean follow-up period and mortality rates were 24.86 ± 38.98 months, 13.04% respectively. The mean survival and reoperation-free time were 179.02 ± 13.78 and 203 ± 10.09 months, respectively. Patients can be managed appropriately with early diagnosis, aggressive medical and surgical treatment via a multidisciplinary approach with customized management according to guidelines in terms of individual characteristics. In cases of worsening hemodynamic status, uncontrolled infection, large and mobile vegetations surgery should be performed as soon as possible

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

1. Kocabaş U, Kaya E, Özerkan FC. Profile of infective endocarditis cases at a tertiary hospital in Turkey: our 15-year experience. Turk Gogus Kalp Damar. 2017;25:52-60.
2. Cahill TJ, Baddour LM, Habib G, et al. Challenges in Infective Endocarditis J Am Coll Cardiol. 2017;69:325-44.
3. Forestier E, Fraisse T, Roubaud-Baudron C, et al. Managing infective endocarditis in the elderly: new issues for an old disease. Clin Interv Aging. 2016;11:1199-206.
4. Selton-Suty C, Célard M, Le Moing V, et al. Preeminence of Staphylococcus aureus in infective endocarditis: a 1-year population-based survey. Clin Infect Dis. 2012;54:1230-9.
5. Murdoch DR, Corey GR, Hoen B, et al. Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the international collaboration on endocarditis prospective cohort study. Arch Inter Med. 2009;169:463-73.
6. Habib G, Lancellotti P, Antunes MJ, et al. 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC) Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J. 2015;36:3075-128.
7. Gaca JG, Sheng S, Daneshmand MA, et al. Outcomes for endocarditis surgery in North America: a simplified risk scoring system. J Thorac Cardiovasc Surg. 2011;141:98-106.
8. Nishimura RA, Otto CM, Bonow RO, et al. 2014 AHA/ACC guideline for the management of patients with valvular heart disease: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014;63:2438-88.
9. Prendergast BD. The changing face of infective endocarditis. Heart. 2006;92:879-85.
10. Dickerman SA, Abrutyn E, Barsic B, et al. The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS). Am Heart J. 2007;154:1086-94.
11. Lodise TP, McKinnon PS, Swiderski L, et al. Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia. Clin Infect Dis. 2003;36:1418-23.
12. Chu VH, Park LP, Athan E, et al. Association between surgical indications, operative risk, and clinical outcome in infective endocarditis: a prospective study from the International Collaboration on Endocarditis. Circulation. 2015;131:131-40.
13. Habib G, Hoen B, Tornos P, et al. Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J. 2009;30:2369-413.
14. Thuny F, Beurtheret S, Mancini J, et al. The timing of surgery influences mortality and morbidity in adults with severe complicated infective endocarditis: a propensity analysis. Eur Heart J. 2011;32:2027-33.
15. Olmos C, Vilacosta I, Fernandez C, et al. Comparison of clinical features of left-sided infective endocarditis involving previously normal versus previously abnormal valves. Am J Cardiol. 2014;114:278-83.
16. Anguera I, Miro JM, Vilacosta I, et al. Aorto-cavitary fistulous tract formation in infective endocarditis: clinical and echocardiographic features of 76 cases and risk factors for mortality. Eur Heart J. 2005;26:288-97.
17. Ragnarsson S, Sjögren J, Stagmo M, et al. Clinical Presentation of Native Mitral Valve Infective Endocarditis Determines Long-Term Outcome after Surgery. J Card Surg. 2015;30:669-76.
18. Hasbun R, Vikram HR, Barakat LA, et al. Complicated leftsided native valve endocarditis in adults: Risk classification for mortality. JAMA. 2003;289:1933-40.
19. Olaison L, Pettersson G. Current best practices and guidelines indications for surgical intervention in infective endocarditis. Infect Dis Clin North Am. 2002;16:453-75.
20. Delahaye F, Célard M, Roth O, et al. Indications and optimal timing for surgery in infective endocarditis Heart. 2004;90:618-20.
21. Kang DH, Kim YJ, Kim SH, et al. Early surgery versus conventional treatment for infective endocarditis. N Engl J Med. 2012;366:2466-73.
22. Lalani T, Cabell CH, Benjamin DK, et al. Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias. Circulation. 2010;121:1005-13.
23. Bannay A, Hoen B, Duval X, et al. The impact of valve surgery on short- and long-term mortality in left-sided infective endocarditis: do differences in methodological approaches explain previous conflicting results? Eur Heart J. 2011;32:2003-15.
24. Disli OM, Karakurt C, Erdil N, et al. Use of autologous pericardium for mitral leaflet reconstruction in a child with endocarditis. Rev Bras Cir Cardiovasc. 2013;28:296-8.
25. Kang DH. Timing of surgery in infective endocarditis. Heart. 2015;101:1786-91.
26. Mihos CG, Pineda AM, Santana O. A Meta-Analysis of Early Versus Delayed Surgery for Valvular Infective Endocarditis Complicated by Embolic Ischemic Stroke Innovations. 2016;11:187-92.
27. Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC Focused Update of the 2014 AHA/ACC Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. J Am Coll Cardiol. 2017;70:252-89.
28. Delahaye F. Is early surgery beneficial in infective endocarditis? A systematic review. Arch Cardiovasc Dis. 2011;104:35-44.
29. Liang F, Song B, Liu R, et al. Optimal timing for early surgery in infective endocarditis: a meta-analysis. Interact CardioVasc Thorac Surg. 2016;22:336-45.
30. Perrotta S, Zubrytska Y. Valve selection in aortic valve endocarditis. Kardiochir Torakochirurgia Pol. 2016;13:203-9.

APA	AKCA B, erdil n, COLAK M, disli o, Battaloglu B (2020). Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. , 9 - 15.
Chicago	AKCA Baris,erdil nevzat,COLAK Mehmet Cengiz,disli olcay murat,Battaloglu Bektas Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. (2020): 9 - 15.
MLA	AKCA Baris,erdil nevzat,COLAK Mehmet Cengiz,disli olcay murat,Battaloglu Bektas Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. , 2020, ss.9 - 15.
AMA	AKCA B,erdil n,COLAK M,disli o,Battaloglu B Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. . 2020; 9 - 15.
Vancouver	AKCA B,erdil n,COLAK M,disli o,Battaloglu B Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. . 2020; 9 - 15.
IEEE	AKCA B,erdil n,COLAK M,disli o,Battaloglu B "Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center." , ss.9 - 15, 2020.
ISNAD	AKCA, Baris vd. "Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center". (2020), 9-15.

APA	AKCA B, erdil n, COLAK M, disli o, Battaloglu B (2020). Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. Medicine Science, 9(1), 9 - 15.
Chicago	AKCA Baris,erdil nevzat,COLAK Mehmet Cengiz,disli olcay murat,Battaloglu Bektas Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. Medicine Science 9, no.1 (2020): 9 - 15.
MLA	AKCA Baris,erdil nevzat,COLAK Mehmet Cengiz,disli olcay murat,Battaloglu Bektas Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. Medicine Science, vol.9, no.1, 2020, ss.9 - 15.
AMA	AKCA B,erdil n,COLAK M,disli o,Battaloglu B Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. Medicine Science. 2020; 9(1): 9 - 15.
Vancouver	AKCA B,erdil n,COLAK M,disli o,Battaloglu B Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center. Medicine Science. 2020; 9(1): 9 - 15.
IEEE	AKCA B,erdil n,COLAK M,disli o,Battaloglu B "Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center." Medicine Science, 9, ss.9 - 15, 2020.
ISNAD	AKCA, Baris vd. "Management of infective endocarditis and long-term outcomes of patients who underwent surgery: The fifteen-year experience of a tertiary care center". Medicine Science 9/1 (2020), 9-15.