Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction

Karagun, Ebru; Caliskan, Eray; ELLİBEŞ KAYA, AŞKI; SUKGEN, GÖKMEN

doi:10.4274/tjod.galenos.2019.23356

Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction

Gökmen SUKGEN, (Özel Muayenehane Kliniği, Kadın Hastalıkları ve Doğum Kliniği, Adana, Türkiye)

Aşkı ELLİBEŞ KAYA, (Düzce Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Düzce, Türkiye)

Ebru KARAGÜN, (Düzce Üniversitesi, Tıp Fakültesi, Dermatoloji Anabilim Dalı, Düzce, Türkiye)

Eray ÇALIŞKAN (Okan Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul, Türkiye)

Turkish Journal of Obstetrics and Gynecology

4 1

Yıl: 2019 Cilt: 16 Sayı: 4 Sayfa Aralığı: 228 - 234 Metin Dili: İngilizce DOI: 10.4274/tjod.galenos.2019.23356 İndeks Tarihi: 30-10-2020

Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction

Öz:

Objective: To investigate the effect of platelet-rich plasma (PRP) injection to the lower one-third of the anterior vaginal wall on sexual function, orgasm, and genitalperception in women with sexual dysfunction.Materials and Methods: Four sessions of PRP were administered to the anterior vaginal wall of 52 female patients with sexual dysfunction and orgasmic disorder[Female Sexual Function Index (FSFI) total score ≤26 orgasmic subdomain score ≤3.75]. Prior to the PRP administrations in each session, the FSFI validated inTurkish, the Female Genital Self-Image Scale (FGSIS), the Female Sexual Distress Scale-Revised (FSDS-R), and Rosenberg’s Self-Esteem Scale were used and in thefinal follow-up, and the Patient Global Impression of Improvement (PGI-I) was performed and the results were analyzed.Results: Following the application of the PRP, the total FSFI score was observed as 27.88±4.80 and the total score was 26 and above in 50% of the patients(p<0.001). Orgasm subdomain scores were found as 2.11±1.20 before the PRP treatment and 4.48±1.14 afterwards (p<0.001). A significant change was observed inall sub-domains after PRP and it was observed that this change started after the first administration (p<0.001). A statistically significant increase was determined inFGSIS genital perception scores, which was significant between the 1st and 2nd months (p<0.001). The FSDS-R scores showed a minimal increase in stress scores asthe application number increased, but a statistically significant decrease was observed in the 4th administration (p<0.001). No statistically significant difference wasfound in Rosenberg Scale scores before and after treatment (p=0.389). High satisfaction was found in PGI-I scores.Conclusion: As a minimally invasive method, PRP administration to the distal anterior vaginal wall may improve female sexuality with high satisfaction.

Anahtar Kelime:

Kadın cinselliğinde memnuniyeti artırmak için alt ön vajinal duvara trombositçe zengin plazma uygulaması

Öz:

Amaç: Bu çalışmanın amacı, seksüel disfonksiyonu olan kadınlarda vagen alt 1/3 anterior duvarına trombositten zengin plazma (PRP) enjeksiyonunun seksüel fonksiyonlara etkisini araştırmaktır. Gereç ve Yöntemler: Seksüel disfonksiyon ve orgazmik bozukluk olan [Female Sexual Function Index (FSFI) total skor 26 ve altı, orgazmik subdomain skor 3,75 ve altı] 52 kadın hastanın vagen anterior duvarına 4 seans PRP uygulandı. PRP öncesi ve her seansta Türkçe’ye valide edilmiş FSFI, the Female Genital SelfImage Scale (FGSIS), The Female Sexual Distress Scale-Revised (FSDS-R), Rosenberg’s Self-Esteem Scale uygulandı ve son kontrolde Patient Global Impression of Improvement (PGI-I) uygulandı, sonuçlar analiz edildi. Bulgular: PRP sonrası, FSFI total skor 27,88±4,80 [anlamlılık ± standart sapma (SD)], %50’de total skorun 26 ve üzerinde olduğu görüldü (p<0,001). Orgazm subdomain skorları PRP öncesi 2,11±1,20 (anlamlılık ± SD), sonrası 4,48±1,14 (anlamlılık ± SD) saptandı (p<0,001). PRP sonrası tüm alt domainlerde anlamlı değişim saptandı ve bu değişimin 1. uygulamadan sonra başladığı görüldü (p<0,001). FGSIS genital algı skorlarında da istatistiksel olarak anlamlı artış saptandı, bu artışın 1.-2. ay arasında belirgin olduğu görüldü (p<0,001). FSDS-R skorlarında uygulama arttıkça stres skorunda minimal artış görüldü ancak 4. uygulamada istatistiksel anlamlı düşüş saptandı (p<0,001). Rosenberg Skala’da tedavi öncesi ve sonrası istatistiksel olarak anlamlı fark saptanmadı (p=0,389). PGI-I skorlarında hastalarda yüksek memnuniyet saptandı. Sonuç: Minimal invaziv bir metot olarak, distal anterior vajinal duvarına PRP uygulaması, kadın cinselliğinde yüksek memnuniyet sağlayabilir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	SUKGEN G, ELLİBEŞ KAYA A, Karagun E, Caliskan E (2019). Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. , 228 - 234. 10.4274/tjod.galenos.2019.23356
Chicago	SUKGEN GÖKMEN,ELLİBEŞ KAYA AŞKI,Karagun Ebru,Caliskan Eray Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. (2019): 228 - 234. 10.4274/tjod.galenos.2019.23356
MLA	SUKGEN GÖKMEN,ELLİBEŞ KAYA AŞKI,Karagun Ebru,Caliskan Eray Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. , 2019, ss.228 - 234. 10.4274/tjod.galenos.2019.23356
AMA	SUKGEN G,ELLİBEŞ KAYA A,Karagun E,Caliskan E Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. . 2019; 228 - 234. 10.4274/tjod.galenos.2019.23356
Vancouver	SUKGEN G,ELLİBEŞ KAYA A,Karagun E,Caliskan E Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. . 2019; 228 - 234. 10.4274/tjod.galenos.2019.23356
IEEE	SUKGEN G,ELLİBEŞ KAYA A,Karagun E,Caliskan E "Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction." , ss.228 - 234, 2019. 10.4274/tjod.galenos.2019.23356
ISNAD	SUKGEN, GÖKMEN vd. "Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction". (2019), 228-234. https://doi.org/10.4274/tjod.galenos.2019.23356

APA	SUKGEN G, ELLİBEŞ KAYA A, Karagun E, Caliskan E (2019). Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish Journal of Obstetrics and Gynecology, 16(4), 228 - 234. 10.4274/tjod.galenos.2019.23356
Chicago	SUKGEN GÖKMEN,ELLİBEŞ KAYA AŞKI,Karagun Ebru,Caliskan Eray Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish Journal of Obstetrics and Gynecology 16, no.4 (2019): 228 - 234. 10.4274/tjod.galenos.2019.23356
MLA	SUKGEN GÖKMEN,ELLİBEŞ KAYA AŞKI,Karagun Ebru,Caliskan Eray Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish Journal of Obstetrics and Gynecology, vol.16, no.4, 2019, ss.228 - 234. 10.4274/tjod.galenos.2019.23356
AMA	SUKGEN G,ELLİBEŞ KAYA A,Karagun E,Caliskan E Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish Journal of Obstetrics and Gynecology. 2019; 16(4): 228 - 234. 10.4274/tjod.galenos.2019.23356
Vancouver	SUKGEN G,ELLİBEŞ KAYA A,Karagun E,Caliskan E Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction. Turkish Journal of Obstetrics and Gynecology. 2019; 16(4): 228 - 234. 10.4274/tjod.galenos.2019.23356
IEEE	SUKGEN G,ELLİBEŞ KAYA A,Karagun E,Caliskan E "Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction." Turkish Journal of Obstetrics and Gynecology, 16, ss.228 - 234, 2019. 10.4274/tjod.galenos.2019.23356
ISNAD	SUKGEN, GÖKMEN vd. "Platelet-rich plasma administration to the lower anterior vaginal wall to improve female sexuality satisfaction". Turkish Journal of Obstetrics and Gynecology 16/4 (2019), 228-234. https://doi.org/10.4274/tjod.galenos.2019.23356