Objective: The aim of the study is to investigate the effectiveness of home exercise program against transcutaneous electrical nerve stimulation (TENS) and supervised exercise in patients with subacromial impingement syndrome (SIS).Material and Methods: Forty-two patients (29 women, 13 men) diagnosed with SIS (stage I and II) were included in the study. The patients were divided into two groups—the supervised group (TENS and supervised physiotherapy program) and the home exercise group. The patients were evaluated at the beginning and at 6 weeks. Numerical rating scale for pain (NRS), goniometer for joint range of motion (ROM), hand dynamometer for muscle strength, modified push-up test for endurance, and functionality for disabilities of the arm, shoulder, and hand questionnaire (DASH), Constant-Murley score (CMS), and timed functional arm and shoulder test (TFAST) were used.Results: Although pain status decreased significantly in both the groups, it decreased more in the supervised group (p≤0.05). Active ROM was significantly increased in both the groups (flexion, abduction, internal and external rotation) (p≤0.05). Endurance, muscle strength, DASH, CMS, and TFAST scores improved significantly in both the groups after treatment (p≤0.05). When the groups were compared, no difference was found (p>0.05).Conclusion: According to the results of our study, exercises performed under the supervision of a physiotherapist and TENS in patients with SIS have similar effects on ROM, muscle strength, and endurance when compared with those with home exercises.