Yıl: 2020 Cilt: 7 Sayı: 2 Sayfa Aralığı: 213 - 224 Metin Dili: İngilizce DOI: 10.5152/ArcHealthSciRes.2020.20047 İndeks Tarihi: 30-10-2020

Novel Coronavirus Disease: Overview and Recent Situation

Öz:
In the last days of 2019, local hospitals in Wuhan city (population of 11 million) reported several pneumonia cases with unknown etiology among people linked to the Huanan Seafood Wholesale Market. The virus, which is thought to be the source of the unknown viral infection, was first identified as a new type of coronavirus on January 7, 2020. With the first case reported in Thailand about a week later, the virus’s spread outside the borders of China became apparent. In an alarmingly short time, the new type of coronavirus disease (called COVID-19) started to gain worldwide recognition with the detection of various COVID-19 cases in multiple countries, including Japan, South Korea, USA, Singapore, France, Germany, Italy, Spain, and England. As a result of its rampant spread and fatal clinical manifestations, the coronavirus outbreak was declared a pandemic on March 11, 2020, by the World Health Organization (WHO). Turkey announced its first confirmed case of COVID-19 on the same date that WHO characterized COVID-19 as a pandemic. As of April 2020, the COVID-19 pandemic has traveled to 209 countries and territories around the world, infecting more than 3 million people. Since specific treatment and vaccine for COVID-19 are not yet available, early case detection and preventive healthcare practices (isolation, social distancing, and personal hygiene) play a critical role in combating the COVID-19 outbreak. This review is intended to build an overall picture of the COVID-19 outbreak based on the available scientific knowledge.
Anahtar Kelime:

Yeni Tip Koronavirüs Hastalığına Genel Bakış ve Son Durum

Öz:
2019 yılının son günlerinde Çin’in 11 milyon nüfuslu Vuhan kentindeki yerel hastaneler, Huanan Deniz Ürünleri ve Canlı Hayvan Marketi’ni yakın zamanda ziyaret etmiş bir grup insanda etiyolojisi bilinmeyen pnömoni vakalarına rastlandığını bildirmiştir. Hastalığın kaynağı olduğu düşünülen virüs 7 Ocak 2020 tarihinde ilk olarak yeni tip koronavirüs (SARS-CoV-2) olarak tanımlanmış ve yaklaşık bir hafta sonra Tayland’ın bildirdiği ilk vakayla birlikte Çin ülke sınırları dışına çıktığı resmiyet kazanmıştır. Aynı ay içerisinde pek çok ülkede (Japonya, Güney Kore, ABD, Singapur, Fransa, Almanya, İtalya, İspanya ve İngiltere) SARS-CoV-2 vakalarının tespit edilmesiyle virüsün sebep olduğu hastalık (COVID-19) küresel bir boyut kazanmaya başlamıştır. Dünya Sağlık Örgütü (DSÖ) tarafından 30 Ocak 2020 tarihinde Uluslararası Halk Sağlığı Acil Durumu olarak duyurulan COVID-19 yaklaşık iki aylık bir zaman diliminde 114 ülkeye yayılmış ve bunun sonucunda 11 Mart 2020 tarihinde pandemik hastalık olarak ilan edilmiştir. Nisan ayına gelindiğinde 209 ülkeye yayılan COVID-19 başta İtalya, İspanya, Fransa, İngiltere ve Amerika Birleşik Devletleri olmak üzere pek çok ülkede hızlı yayılımına devam etmiş ve her geçen gün insan sağlığı için daha da ciddi bir tehdit konumuna gelmiştir. Türkiye’deki ilk COVID-19 vakası DSÖ’nün hastalığı pandemi ilan ettiği tarih olan 11 Mart 2020’de rapor edilmiş olup, Nisan sonu itibariyle salgının yayılma hızı azalma eğilimi göstermeye başlamıştır. Henüz koruyucu aşıların geliştirilememiş olması ve mevcut antiviral ilaçların etkisiz kalması, COVID-19 salgınıyla mücadelede erken vaka tespiti ve koruyucu sağlık hizmeti uygulamalarını (izolasyon, sosyal mesafe, kişisel hijyen) ön plana çıkarmaktadır. Bu derleme devam eden COVID-19 salgınına ilişkin tüm faktörlerin ve mevcut durumun bilimsel bir şekilde gözden geçirilmesi amacıyla hazırlanmıştır.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Derleme Erişim Türü: Erişime Açık
  • 1. Hamre D, Procknow JJ. A New Virus Isolated From the Human Respiratory Tract. Proc Soc Exp Biol Med 1966; 121: 190-3.
  • 2. Tyrrell D, Bynoe M. Cultivation of Viruses From a High Proportion of Patients With Colds. Lancet 1966: 76-7.
  • 3. McIntosh K, Dees JH, Becker WB, Kapikian AZ, Chanock RM. Recovery in Tracheal Organ Cultures of Novel Viruses From Patients With Respiratory Disease. Proc Natl Acad Sci USA 1967; 57: 933.
  • 4. Witte K, Tajima M, Easterday B. Morphologic Characteristics and Nucleic Acid Type of Transmissible Gastroenteritis Virus of Pigs. Arch Gesamte Virusforsch 1968; 23: 53-70.
  • 5. Meo S, Alhowikan A, Al-Khlaiwi T, Meo I, Halepoto D, Iqbal M, et al. Novel Coronavirus 2019-nCoV: Prevalence, Biological and Clinical Characteristics Comparison With SARS-CoV and MERS-CoV. Eur Rev Med Pharmacol Sci 2020; 24: 2012-9.
  • 6. Burrell CJ, Howard CR, Murphy FA. Fenner and White's medical virology: Academic Press; 2016.
  • 7. Zhang T, Wu Q, Zhang Z. Probable Pangolin Origin of SARS-Cov-2 Associated With the COVID-19 Outbreak. Curr Biol 2020; 30: 1346-51.
  • 8. Brook CE, Boots M, Chandran K, Dobson AP, Drosten C, Graham AL, et al. Accelerated Viral Dynamics in Bat Cell Lines, With Implications for Zoonotic Emergence. eLife 2020; 9:e48401.
  • 9. Chan JF-W, Yuan S, Kok K-H, To KK-W, Chu H, Yang J, et al. A Familial Cluster of Pneumonia Associated With the 2019 Novel Coronavirus Indicating Person-to-Person Transmission: A Study of a Family Cluster. Lancet 2020; 395: 514-23.
  • 10. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical Features of Patients Infected With 2019 Novel Coronavirus in Wuhan, China. Lancet 2020; 395: 497-506.
  • 11. Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, et al. ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia. J Virol 2005; 79: 14614-21.
  • 12. Liu Y, Gayle AA, Wilder-Smith A, Rocklöv J. The Reproductive Number of COVID-19 Is Higher Compared to SARS Coronavirus. J Travel Med 2020; 27: taaa021
  • 13. Li Q, Guan X, Wu P, Wang X, Zhou L, Tong Y, et al. Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia. N Engl J Med 2020; 382: 1199-207.
  • 14. World Health Organization (WHO). Coronavirus Disease 2019 (COVID-19): Situation report. 2020. Report No:67.
  • 15. Perisetti A, Gajendran M, Boregowda U, Bansal P, Goyal H. COVID‐19 and Gastrointestinal Endoscopies: Current Insights and Emergent Strategies. Dig Endosc 13 April 2020. [Epub Ahead of Print]
  • 16. Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG. Into The Eye of the Cytokine Storm. Microbiol Mol Biol Rev 2012; 76: 16-32.
  • 17. Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The Origin, Transmission and Clinical Therapies on Coronavirus Disease 2019 (COVID-19) Outbreak- An Update on the Status. Mil Med Res 2020; 7: 1-10.
  • 18. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA 2020; 323: 1239-42.
  • 19. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med 2020; 382: 1708-20.
  • 20. World Health Organization (WHO). WHO Director-General's opening remarks at the media briefing on COVID-19 [Internet] 2020. Available from: https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---3-march-2020.
  • 21. Verity R, Okell L, Dorigatti I. Correction to Lancet Infect Dis 2020; 20: 275-6.
  • 22. Lazzerini M, Putoto G. COVID-19 In Italy: Momentous Decisions and Many Uncertainties. The Lancet Glob Health 2020; 8: e641-2.
  • 23. Surveillances V. The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19)-China, 2020. China CDC Weekly 2020; 2: 113-22.
  • 24. Istituto Superiore di Sanità. Integrated surveillance of COVID-19 in Italy [Internet] 2020. Available from: https://www.epicentro.iss.it/en/coronavirus/bollettino/Report-COVID-2019_16_april_2020.pdf.
  • 25. Jin YH, Cai L, Cheng ZS, Cheng H, Deng T, Fan YP, et al. A Rapid Advice Guideline for the Diagnosis and Treatment of 2019 Novel Coronavirus (2019-nCoV) Infected Pneumonia (standard version). Mil Med Res 2020; 7: 4.
  • 26. Centers for Disease Control and Prevention (CDC). How to Protect Yourself & Others [Internet] 2020. [Updated: 2020 April; Cited: 2020 April 25] Available from: https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/prevention.html.
  • 27. Mitjà O, Clotet B. Use of Antiviral Drugs to Reduce COVID-19 Transmission. Lancet Glob Health 2020; 8: e639-40.
  • 28. Liu Y, Li J, Feng Y. Critical Care Response to a Hospital Outbreak of the 2019-nCoV Infection in Shenzhen, China. Crit Care 2020; 24: 56.
  • 29. Saey TH. Repurposed drugs may help scientists fight the new coronavirus [Internet] 2020. Available from: https://www.sciencenews.org/article/coronavirus-covid19-repurposed-treatments-drugs .
  • 30. Wang Z, Chen X, Lu Y, Chen F, Zhang W. Clinical Characteristics and Therapeutic Procedure for Four Cases With 2019 Novel Coronavirus Pneumonia Receiving Combined Chinese and Western Medicine Treatment. Biosci Trends 2020; 14: 64-8
  • 31. Cao B, Wang Y, Wen D, Liu W, Wang J, Fan G, et al. A Trial of Lopinavir-Ritonavir in Adults Hospitalized With Severe Covid-19. N Engl J Med 2020; 382: 1787-99.
  • 32. Johnson J. Lack of Evidence to Support Use of Darunavir-Based Treatments for SARS-CoV-2 [Internet] 2020. Available from: https://www.jnj.com/lack-of-evidence-to-support-darunavir-based-hiv-treatments-for-coronavirus.
  • 33. Dong L, Hu S, Gao J. Discovering Drugs to Treat Coronavirus Disease 2019 (COVID-19). Drug Discov Ther 2020; 14: 58-60.
  • 34. Chen C, Huang J, Cheng Z, Wu J, Chen S, Zhang Y, et al. Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial. MedRxiv 15 April 2020. [Epub Ahead of Print]
  • 35. Al-Tawfiq JA, Al-Homoud AH, Memish ZA. Remdesivir as a Possible Therapeutic Option for the COVID-19. Trav Med Infect Dis 2020; 34: 101615.
  • 36. Amirian ES, Levy JK. Current Knowledge About the Antivirals Remdesivir (GS-5734) and GS-441524 as Therapeutic Options for Coronaviruses. One Health 2020; 9: 100128.
  • 37. Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al. First Case of 2019 Novel Coronavirus in the United States. N Engl J Med 2020; 382: 929-36.
  • 38. Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A Pneumonia Outbreak Associated with a New Coronavirus of Probable Bat Origin. Nature 2020; 579: 270-3.
  • 39. Tai W, He L, Zhang X, Pu J, Voronin D, Jiang S, et al. Characterization of the Receptor-Binding Domain (RBD) of 2019 Novel Coronavirus: Implication for Development of RBD Protein as a Viral Attachment Inhibitor and Vaccine. Cell Mol Immunol 2020; 17: 613-20.
  • 40. Dhama K, Sharun K, Tiwari R, Sircar S, Bhat S, Malik YS, et al. Coronavirus Disease 2019-COVID-19. Preprints 2020; 2020030001.
  • 41. Koch S PW. The Count of Companies Developing Vaccines for Coronavirus Rises [Internet] 2020. Available from: https://www.biocentury.com/article/304412.
  • 42. Khamsi R. If a Coronavirus Vaccine Arrives, Can the World Make Enough? Nature 2020; 580: 578-80
  • 43. Chen W-H, Strych U, Hotez PJ, Bottazzi ME. The SARS-CoV-2 Vaccine Pipeline: An Overview. Curr Trop Med Rep 2020; 1-4.
  • 44. GSK and Vir Biotechnology Enter Collaboration to Find Coronavirus [Internet] 2020. Available from: https://www.gsk.com/en-gb/media/press-releases/gsk-and-vir-biotechnology-enter-collaboration-to-find-coronavirus-solutions/.
  • 45. Pharmaceuticals I. Inovio Collaborating with Beijing Advaccine to Advance INO-4800 Vaccine Against New Coronavirus In China [Internet] 2020. Available from: https://www.prnewswire.com/news-releases/inovio-collaborating-with-beijing-advaccine-to-advance-ino-4800-vaccine-against-new-coronavirus-in-china-300995916.html.
  • 46. World Health Organization (WHO). International Clinical Trials Registry Platform (ICTRP) [Internet] 2020. Available from: https://www.who.int/ictrp/en/.
  • 47. World Health Organization (WHO). Coronavirus disease 2019 (COVID-19): Situation report. 2020. Report No:59.
  • 48. Worldometers. COVID-19 Coronavirus Pandemic [Internet] 2020. Available from: https://www.worldometers.info/coronavirus/#countries.
  • 49. Shanmugaraj B, Siriwattananon K, Wangkanont K, Phoolcharoen W. Perspectives on Monoclonal Antibody Therapy as Potential Therapeutic Intervention for Coronavirus Disease-19 (COVID-19). Asian Pac J Allergy Immunol 2020; 38: 10-8.
  • 50. Fung TS, Liu DX. Human Coronavirus: Host-Pathogen Interaction. Annu Rev Microbiol 2019; 73: 529-57.
APA Oksel C, BILGI E, BAŞLAR M, Çeşmeli S, Tomak A, ÖZTANRIKULU B (2020). Novel Coronavirus Disease: Overview and Recent Situation. , 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
Chicago Oksel Ceyda,BILGI EYÜP,BAŞLAR Muhammet Semih,Çeşmeli Selin,Tomak Aysel,ÖZTANRIKULU Berçem Dilan Novel Coronavirus Disease: Overview and Recent Situation. (2020): 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
MLA Oksel Ceyda,BILGI EYÜP,BAŞLAR Muhammet Semih,Çeşmeli Selin,Tomak Aysel,ÖZTANRIKULU Berçem Dilan Novel Coronavirus Disease: Overview and Recent Situation. , 2020, ss.213 - 224. 10.5152/ArcHealthSciRes.2020.20047
AMA Oksel C,BILGI E,BAŞLAR M,Çeşmeli S,Tomak A,ÖZTANRIKULU B Novel Coronavirus Disease: Overview and Recent Situation. . 2020; 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
Vancouver Oksel C,BILGI E,BAŞLAR M,Çeşmeli S,Tomak A,ÖZTANRIKULU B Novel Coronavirus Disease: Overview and Recent Situation. . 2020; 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
IEEE Oksel C,BILGI E,BAŞLAR M,Çeşmeli S,Tomak A,ÖZTANRIKULU B "Novel Coronavirus Disease: Overview and Recent Situation." , ss.213 - 224, 2020. 10.5152/ArcHealthSciRes.2020.20047
ISNAD Oksel, Ceyda vd. "Novel Coronavirus Disease: Overview and Recent Situation". (2020), 213-224. https://doi.org/10.5152/ArcHealthSciRes.2020.20047
APA Oksel C, BILGI E, BAŞLAR M, Çeşmeli S, Tomak A, ÖZTANRIKULU B (2020). Novel Coronavirus Disease: Overview and Recent Situation. Archives of health science and research (Online), 7(2), 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
Chicago Oksel Ceyda,BILGI EYÜP,BAŞLAR Muhammet Semih,Çeşmeli Selin,Tomak Aysel,ÖZTANRIKULU Berçem Dilan Novel Coronavirus Disease: Overview and Recent Situation. Archives of health science and research (Online) 7, no.2 (2020): 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
MLA Oksel Ceyda,BILGI EYÜP,BAŞLAR Muhammet Semih,Çeşmeli Selin,Tomak Aysel,ÖZTANRIKULU Berçem Dilan Novel Coronavirus Disease: Overview and Recent Situation. Archives of health science and research (Online), vol.7, no.2, 2020, ss.213 - 224. 10.5152/ArcHealthSciRes.2020.20047
AMA Oksel C,BILGI E,BAŞLAR M,Çeşmeli S,Tomak A,ÖZTANRIKULU B Novel Coronavirus Disease: Overview and Recent Situation. Archives of health science and research (Online). 2020; 7(2): 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
Vancouver Oksel C,BILGI E,BAŞLAR M,Çeşmeli S,Tomak A,ÖZTANRIKULU B Novel Coronavirus Disease: Overview and Recent Situation. Archives of health science and research (Online). 2020; 7(2): 213 - 224. 10.5152/ArcHealthSciRes.2020.20047
IEEE Oksel C,BILGI E,BAŞLAR M,Çeşmeli S,Tomak A,ÖZTANRIKULU B "Novel Coronavirus Disease: Overview and Recent Situation." Archives of health science and research (Online), 7, ss.213 - 224, 2020. 10.5152/ArcHealthSciRes.2020.20047
ISNAD Oksel, Ceyda vd. "Novel Coronavirus Disease: Overview and Recent Situation". Archives of health science and research (Online) 7/2 (2020), 213-224. https://doi.org/10.5152/ArcHealthSciRes.2020.20047