Is Vitamin D Important for Elderly Patients in Intensive Care?

Turkmen, Aygen; KESICI, Sevgi; KURNAZ, Muhammed Murat

doi:10.4274/jarem.galenos.2019.2865

Is Vitamin D Important for Elderly Patients in Intensive Care?

Muhammed Murat KURNAZ, (Giresun Üniversitesi, Prof.Dr.A. İlhan Özdemir Eğitim ve Araştırma Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, Giresun, Türkiye)

Sevgi KESİCİ, (Türkiye Sağlık Bilimleri Üniversitesi, Hamidiye Etfal Eğitim ve Araştırma Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, İstanbul, Türkiye)

Ülkü Aygen TÜRKMEN (Türkiye Sağlık Bilimleri Üniversitesi, Gaziosmanpaşa Eğitim ve Araştırma Hastanesi, Anesteziyoloji ve Reanimasyon Kliniği, İstanbul, Türkiye)

JAREM

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Yıl: 2020 Cilt: 10 Sayı: 2 Sayfa Aralığı: 117 - 121 Metin Dili: İngilizce DOI: 10.4274/jarem.galenos.2019.2865 İndeks Tarihi: 30-10-2020

Is Vitamin D Important for Elderly Patients in Intensive Care?

Öz:

Objective: According to the World Health Organization’s old age classification, 65-74 years is considered as young-old, 75-84 years as middle-old,and over 85 years as old-old. Effects of vitamin D on cardiac, renal, and endocrine diseases are closely associated with morbidity/mortality in intensivecare units. This study evaluated the difference in vitamin D levels of intensive care patients below and above 75 years, and the associations betweenvitamin D levels and age as well as mortality/organ failure in both groups.Methods: This study was designed as a retrospective, non-interventional, non-drug, observational clinical trial. Age, gender, vitamin D, and acutephysiology and chronic health evaluation II (APACHE II) and sequential organ failure assessment scores on admission to the intensive care unit wererecorded.Results: Of all patients, 60 were female and 31 were male. The mean age was 77.7±13.8 years. There were 29 patients aged below 75 years and 62patients above. The mean vitamin D level was 13.7510 ng/mL-1. The mean APACHE II score of patients of or above 75 years was significantly higherthan that of patients below 75 years (p=0.024). There was a significant negative correlation between age and vitamin D in patients of or above 75years (p=0.042).Risk factors associated with vitamin D deficiency include age, gender, lifestyle, ethnic origin, diet, medical history, drugs, and acute critical illness.With aging, the concentration of 7-dehydrocholesterol in the skin decreases, as well as the vitamin D3-forming capacity of the skin. In this study lowervitamin D levels were detected with increasing age in intensive care unit patients.Conclusion: No significant relationship was detected between age and vitamin D levels in patients below 75 years whereas a significant decrease invitamin D level with increasing age was detected in patients of or above 75 years (p=0,042).

Anahtar Kelime:

Yoğun Bakımdaki Yaşlı Hastalarda Vitamin D Önemli Midir?

Öz:

Amaç: Vitamin D’nin kardiyak, renal ve endokrin hastalıklardaki etkileri yoğun bakım ünitelerinde morbitide ve mortalite ile yakından ilişkilidir. Vitamin D seviyesinin 20 ng mL-1 altında olması ciddi yetersizlik olarak kabul edilmektedir. Bu çalışmada 75 yaş üstündeki orta ve ileri yaşlı yoğun bakım hastalarının D vitamini seviyeleri arasında farklılık ve her iki grupta yaş ile D vitamin düzeyleri arasında ilişki olup olmadığı araştırıldı. Yöntemler: Bu çalışma retrospektif, girişimsel olmayan, ilaç dışı, gözlemsel bir klinik çalışma olarak tasarlanmıştır. Yoğun bakım ünitesine giriş sırasındaki yaş, cinsiyet, D vitamini, akut fizyoloji ve kronik sağlık değerlendirmesi II (APACHE II) ve sıralı organ yetmezliği değerlendirmesi skorları kaydedildi. Bulgular: Hastaların 60’ı kadın, 31’i erkekti. Ortalama yaş 77,7±13,8 idi. Doksan bir hastanın 29’u, 75 yaş altı; 62’si 75 yaş ve üzerindeydi. Tüm hastalar incelendiğinde D vitamini ortalama değeri 13,7510 ng mL-1 bulundu.Yetmiş beş yaş üstü hasta grubunda APACHE II skoru ortalaması, 75 yaş altı hasta grubundan anlamlı olarak yüksekti (p=0,024). Yetmiş beş yaş ve üstü grubunda; yaş ile D vitamini düzeyleri arasında anlamlı negatif ilişki vardı (p=0,042). Sonuç: Yetmiş beş yaş ve üstü grubunda; yaş ile D vitamini düzeyleri arasında anlamlı negatif ilişki vardı (p=0,042).

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	KURNAZ M, KESICI S, Turkmen A (2020). Is Vitamin D Important for Elderly Patients in Intensive Care?. , 117 - 121. 10.4274/jarem.galenos.2019.2865
Chicago	KURNAZ Muhammed Murat,KESICI Sevgi,Turkmen Aygen Is Vitamin D Important for Elderly Patients in Intensive Care?. (2020): 117 - 121. 10.4274/jarem.galenos.2019.2865
MLA	KURNAZ Muhammed Murat,KESICI Sevgi,Turkmen Aygen Is Vitamin D Important for Elderly Patients in Intensive Care?. , 2020, ss.117 - 121. 10.4274/jarem.galenos.2019.2865
AMA	KURNAZ M,KESICI S,Turkmen A Is Vitamin D Important for Elderly Patients in Intensive Care?. . 2020; 117 - 121. 10.4274/jarem.galenos.2019.2865
Vancouver	KURNAZ M,KESICI S,Turkmen A Is Vitamin D Important for Elderly Patients in Intensive Care?. . 2020; 117 - 121. 10.4274/jarem.galenos.2019.2865
IEEE	KURNAZ M,KESICI S,Turkmen A "Is Vitamin D Important for Elderly Patients in Intensive Care?." , ss.117 - 121, 2020. 10.4274/jarem.galenos.2019.2865
ISNAD	KURNAZ, Muhammed Murat vd. "Is Vitamin D Important for Elderly Patients in Intensive Care?". (2020), 117-121. https://doi.org/10.4274/jarem.galenos.2019.2865

APA	KURNAZ M, KESICI S, Turkmen A (2020). Is Vitamin D Important for Elderly Patients in Intensive Care?. JAREM, 10(2), 117 - 121. 10.4274/jarem.galenos.2019.2865
Chicago	KURNAZ Muhammed Murat,KESICI Sevgi,Turkmen Aygen Is Vitamin D Important for Elderly Patients in Intensive Care?. JAREM 10, no.2 (2020): 117 - 121. 10.4274/jarem.galenos.2019.2865
MLA	KURNAZ Muhammed Murat,KESICI Sevgi,Turkmen Aygen Is Vitamin D Important for Elderly Patients in Intensive Care?. JAREM, vol.10, no.2, 2020, ss.117 - 121. 10.4274/jarem.galenos.2019.2865
AMA	KURNAZ M,KESICI S,Turkmen A Is Vitamin D Important for Elderly Patients in Intensive Care?. JAREM. 2020; 10(2): 117 - 121. 10.4274/jarem.galenos.2019.2865
Vancouver	KURNAZ M,KESICI S,Turkmen A Is Vitamin D Important for Elderly Patients in Intensive Care?. JAREM. 2020; 10(2): 117 - 121. 10.4274/jarem.galenos.2019.2865
IEEE	KURNAZ M,KESICI S,Turkmen A "Is Vitamin D Important for Elderly Patients in Intensive Care?." JAREM, 10, ss.117 - 121, 2020. 10.4274/jarem.galenos.2019.2865
ISNAD	KURNAZ, Muhammed Murat vd. "Is Vitamin D Important for Elderly Patients in Intensive Care?". JAREM 10/2 (2020), 117-121. https://doi.org/10.4274/jarem.galenos.2019.2865