Yıl: 2020 Cilt: 10 Sayı: 2 Sayfa Aralığı: 200 - 203 Metin Dili: İngilizce DOI: 10.4274/jarem.galenos.2020.3301 İndeks Tarihi: 31-10-2020

Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma

Öz:
Lipomas are benign mesenchymal neoplasms. Angiolipoma is a variant of ordinary lipomas, characterized by adipocytic cells as well as capillaryvascular clusters. Atypical lipomatous tumors are local aggressive mesenchymal neoplasms which include atypical stromal cells. They frequently arisein the deep thigh of the lower extremity. They have four histologic subtypes. So far, there aren’t any case of angiolipoma with malignant transformationor atypical lipomatous tumor with angiolipoma-like areas in the English literature. Here we presented a case of atypical lipomatous tumor whichwas quite like angiolipoma. It was composed of mature fat with focal cytologic atypia and also accompanying diffuse capillary vessels. If there is alarge-diameter and deeply located angiolipoma-like lesion, careful examination is required to rule out a liposarcoma. Liposarcomas may be rarelydedifferentiate or metastatic. It is not possible to verify that if the case is a variant of liposarcoma or it is a malignant transformation of angiolipoma.
Anahtar Kelime:

Anjiyolipoma Benzeyen Atipik Lipomatöz Tümör/İyi Diferansiye Liposarkom

Öz:
Lipomlar iyi huylu mezenkimal neoplazmlardır. Anjiyolipom ise adipositik hücrelerin yanı sıra kılcal damar kümeleri ile karakterize edilen sıradan bir lipom varyantıdır. Atipik lipomatoz tümörler atipik stromal hücreler ile karekterize lokal agresif mezenkimal neoplazmlardır. Sıklıkla alt ekstremitelerde derin yerleşimli olarak ortaya çıkarlar. Dört histolojik alt tipi mevcuttur. Şimdiye kadar, İngiliz literatüründe malign transformasyonlu herhangi bir anjiyolipom veya anjiyolipom benzeri alanlara sahip atipik lipomatöz tümör tanımlanmamıştır. Biz burada fokal sitolojik atipisi olan, matür yağ hücreleri ve eşlik eden yaygın kılcal damarlardan oluşan anjiyolipom benzeri bir atipik lipomatöz tümör olgusunu sunduk. Büyük çaplı ve derin yerleşimli anjiyolipom benzeri lezyonlarda, liposarkomu ekarte etmek için dikkatli inceleme yapmak gerekir. Liposarkomlar nadiren dediferansiye veya metastatik olabilir. Bizim olgunun liposarkomun bir varyantı mı yoksa anjiyolipomun malign transformasyonu mu olduğu konusu tartışmalıdır
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık
  • 1. Lin JJ, Lin F. Two entities in angiolipoma. A study of 459 cases of lipoma with review of literature on infiltrating angiolipoma. Cancer 1974; 34: 720-7.
  • 2. Bowen JT. Multiple subcutaneous hemangiomas, together with multiple lipomas, occurring in enormous numbers in an otherwise healthy, muscular subject. Am J Med Sci 1912; 144: 189-92.
  • 3. Howard WR, Helwig EB. Angiolipoma. Arch Dermatol 1960; 82: 924-31.
  • 4. Gonzalez-Crussi F, Enneking WF, Arean VM. Infiltrating angiolipoma. J Bone Joint Surg Am 1966; 48: 1111-24.
  • 5. Thway K, Flora R, Shah C, Olmos D, Fisher C. Diagnostic utility of p16, CDK4, and MDM2 as an immunohistochemical panel in distinguishing well-differentiated and dedifferentiated liposarcomas from other adipocytic tumors. Am J Surg Pathol 2012: 36: 462-9.
  • 6. Christodoulidou M, Khetrapal P, Edmunds L, Muneer A. Paratesticular liposarcoma and contralateral angiolipoma in a 60-year-old patient. BMJ Case Rep 2015: bcr2015212078.
  • 7. Kacar S, Kuran S, Temucin T, Odemis B, Karadeniz N, Sasmaz N. Rectal angiolipoma: A case report and review of literature. World J Gastroenterol 2007; 13: 1460-5.
  • 8. Lou XH, Chen WG, Ning LG, Chen HT, Xu GQ. Multiple gastric angiolipomas: A case report. World J Clin Cases 2019; 7: 778‐84.
  • 9. Kato K, Matsuda M, Onodera K, Sakata H, Kobayashi T, Kasai S. Angiolipoma of the colon with right lower quadrant abdominal pain. Dig Surg 1999; 16: 441-4.
  • 10. Lindberg MR, Lucas D, Gardner JM, Cassarino DS, Stallings-Archer K. Tumors of Adipose Tissue. In Diagnostic pathology: Soft tissue tumors, 2nded. Philadelphia: Elsevier; 2016. p.52-55
  • 11. Enzinger FM, Goldblum JR, Folpe AL, Weiss SW. Benign Lipomatous Tumors. In Enzinger and Weiss’s soft tissue tumors, 6nded. Philadelphia: Saunders; 2014. p.444-83.
APA saygın i, KORKMAZ A, cakir e (2020). Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. , 200 - 203. 10.4274/jarem.galenos.2020.3301
Chicago saygın ismail,KORKMAZ Ayla,cakir emel Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. (2020): 200 - 203. 10.4274/jarem.galenos.2020.3301
MLA saygın ismail,KORKMAZ Ayla,cakir emel Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. , 2020, ss.200 - 203. 10.4274/jarem.galenos.2020.3301
AMA saygın i,KORKMAZ A,cakir e Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. . 2020; 200 - 203. 10.4274/jarem.galenos.2020.3301
Vancouver saygın i,KORKMAZ A,cakir e Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. . 2020; 200 - 203. 10.4274/jarem.galenos.2020.3301
IEEE saygın i,KORKMAZ A,cakir e "Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma." , ss.200 - 203, 2020. 10.4274/jarem.galenos.2020.3301
ISNAD saygın, ismail vd. "Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma". (2020), 200-203. https://doi.org/10.4274/jarem.galenos.2020.3301
APA saygın i, KORKMAZ A, cakir e (2020). Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. JAREM, 10(2), 200 - 203. 10.4274/jarem.galenos.2020.3301
Chicago saygın ismail,KORKMAZ Ayla,cakir emel Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. JAREM 10, no.2 (2020): 200 - 203. 10.4274/jarem.galenos.2020.3301
MLA saygın ismail,KORKMAZ Ayla,cakir emel Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. JAREM, vol.10, no.2, 2020, ss.200 - 203. 10.4274/jarem.galenos.2020.3301
AMA saygın i,KORKMAZ A,cakir e Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. JAREM. 2020; 10(2): 200 - 203. 10.4274/jarem.galenos.2020.3301
Vancouver saygın i,KORKMAZ A,cakir e Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma. JAREM. 2020; 10(2): 200 - 203. 10.4274/jarem.galenos.2020.3301
IEEE saygın i,KORKMAZ A,cakir e "Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma." JAREM, 10, ss.200 - 203, 2020. 10.4274/jarem.galenos.2020.3301
ISNAD saygın, ismail vd. "Angiolipoma-like Atypical Lipomatous Tumor/Welldifferentiated Liposarcoma". JAREM 10/2 (2020), 200-203. https://doi.org/10.4274/jarem.galenos.2020.3301