Febrile seizures: is there a significance of chronological ranking of fever and seizure?

Cokyaman, Turgay

Febrile seizures: is there a significance of chronological ranking of fever and seizure?

Turgay ÇOKYAMAN (Cengiz Gökçek Kadın Doğum ve Çocuk Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, Çocuk Nörolojisi Bilim Dalı, Gaziantep, Türkiye)

Aile Hekimliği ve Palyatif Bakım

3 0

Yıl: 2019 Cilt: 4 Sayı: 2 Sayfa Aralığı: 57 - 61 Metin Dili: İngilizce İndeks Tarihi: 02-11-2020

Febrile seizures: is there a significance of chronological ranking of fever and seizure?

Öz:

Introduction:Seizures observed in febrile disease periods in healthy children aged from 3 months to 6 years are known as febrile seizures (FS).There is usually a chronological sequence involving seizure following fever in most FS, but some cases may not follow this pattern. This studyinvestigated the chronological relation between fever and convulsion and whether clinical and laboratory findings affect this.Methods:Patients with FS between 1 December, 2015, and 1 April, 2016, were included in this study. Cases with a regular fever plus seizurechronological sequence were classified as classical FS. Without a regular chronological sequence, fever after seizure, were classified as nonclassical FS. The effect on both groups of parameters such as gender, age, height, weight, type of FS (simple or complex), previous history of FS,family history of FS, family history of epilepsy, qualitative c-reactive protein (CRP) and white blood cell (WBC) count were evaluated.Results:Twenty-seven percent of FS were non-classical and 73% were classical. Negative CRP and low WBC emerged as significant predictorsof non-classical FS at binary logistic regression (OR=1.388, 95% CI 1.051-1.834 and OR=9.021, 95% CI 1.298-62.702, respectively). Other factorssuch as gender, age, height, weight, type of FS, previous history of FS, familyhistory of FS, familyhistory of epilepsyhad no effect in terms ofnonclassic FS.Conclusions:Acute inflammatory response findings such as increased CRP, WBC and fever may not accompany in non-classical FS. Althoughthe diagnosis of FS is correct in such cases, misunderstandings may occur between the physician and parents because of the nomenclatureemployed.

Anahtar Kelime:

Febril nöbetler: Ateş sonrası nöbet zamansal sıralamasının bir önemi var mıdır?

Öz:

Giriş: 3 ay-6 yaş arası sağlıklı çocuklarda ateşli hastalık dönemlerinde görülen nöbetlere febril nöbetler (FN)denilmektedir. FN’lerin çoğunda ateş sonrası nöbet zamansal sıralaması görülmekte iken bazı vakalarda bu durum görülmemektedir. Bu çalışmada FN’li hastalarda ateş ve nöbetin zamansal sıralaması ve klinik ve laboratuar bulguların bu zamansal sıralamaya etkilerinin olup olmadığı araştırılmıştır. Yöntem: 1 Aralık 2015 ve 1 Nisan 2016 tarihleri arasında FN tanısı alan hastalar çalışmaya alındı. Ateş sonrası nöbet zamansal sıralaması gösteren vakalar klasik FN olarak sınıflandırıldı. Ateş sonrası nöbet zamansal sıralaması göstermeyen vakalar ise klasik olmayan FN olarak sınıflandırıldı. Cinsiyet, yaş, boy, vücut ağırlığı, febril nöbet tipi (basit, kompleks), daha önce geçirilmiş FN hikayesi varlığı, ailede FN hikayesi olması, ailede epilepsi varlığı, kalitatif C-reaktif protein (CRP) ve beyaz kan hücre (WBC) sayısından oluşan kategorik ve sayısal değişkenlerinin klasik ve klasik olmayan FN’lere etkisi değerlendirildi. Bulgular: Hastaların %73’ü klasik, %27’si ise klasik olmayan FN tanısı aldı. Gruplar arası karşılaştırmalarda yalnız WBC sayısı farklı bulundu ve klasik olmayan FN grubunda anlamlı düzeyde düşüktü. İkili lojistik regresyon analizi sonucu negatif kalitatif CRP ve düşük WBC sayısının klasik olmayan FN’ler için anlamlı prediktörler olduğu ortaya çıktı (sırasıyla OR=1,388; 95%CI 1,051-1,834 ve OR=9,021; 95%CI 1,298-62,702). Sonuç: Klasik olmayan FN’lerde ateş, pozitif CRP yanıtı ve WBC sayısı artışı gibi akut inflamatuar yanıtın göstergeleri görülmeyebilir. Bu tarz vakalarda FN tanısı doğru olsa da tıbbi isimlendirmeden kaynaklanan hekim ve ebeveyn iletişim sorunları doğabilmektedir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Cokyaman T (2019). Febrile seizures: is there a significance of chronological ranking of fever and seizure?. , 57 - 61.
Chicago	Cokyaman Turgay Febrile seizures: is there a significance of chronological ranking of fever and seizure?. (2019): 57 - 61.
MLA	Cokyaman Turgay Febrile seizures: is there a significance of chronological ranking of fever and seizure?. , 2019, ss.57 - 61.
AMA	Cokyaman T Febrile seizures: is there a significance of chronological ranking of fever and seizure?. . 2019; 57 - 61.
Vancouver	Cokyaman T Febrile seizures: is there a significance of chronological ranking of fever and seizure?. . 2019; 57 - 61.
IEEE	Cokyaman T "Febrile seizures: is there a significance of chronological ranking of fever and seizure?." , ss.57 - 61, 2019.
ISNAD	Cokyaman, Turgay. "Febrile seizures: is there a significance of chronological ranking of fever and seizure?". (2019), 57-61.

APA	Cokyaman T (2019). Febrile seizures: is there a significance of chronological ranking of fever and seizure?. Aile Hekimliği ve Palyatif Bakım, 4(2), 57 - 61.
Chicago	Cokyaman Turgay Febrile seizures: is there a significance of chronological ranking of fever and seizure?. Aile Hekimliği ve Palyatif Bakım 4, no.2 (2019): 57 - 61.
MLA	Cokyaman Turgay Febrile seizures: is there a significance of chronological ranking of fever and seizure?. Aile Hekimliği ve Palyatif Bakım, vol.4, no.2, 2019, ss.57 - 61.
AMA	Cokyaman T Febrile seizures: is there a significance of chronological ranking of fever and seizure?. Aile Hekimliği ve Palyatif Bakım. 2019; 4(2): 57 - 61.
Vancouver	Cokyaman T Febrile seizures: is there a significance of chronological ranking of fever and seizure?. Aile Hekimliği ve Palyatif Bakım. 2019; 4(2): 57 - 61.
IEEE	Cokyaman T "Febrile seizures: is there a significance of chronological ranking of fever and seizure?." Aile Hekimliği ve Palyatif Bakım, 4, ss.57 - 61, 2019.
ISNAD	Cokyaman, Turgay. "Febrile seizures: is there a significance of chronological ranking of fever and seizure?". Aile Hekimliği ve Palyatif Bakım 4/2 (2019), 57-61.