Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers

erdiş, eda; Yücel, Birsen

doi:10.32448/entupdates.696940

Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers

Eda ERDİŞ, (Sivas Cumhuriyet Üniversitesi, Tıp Fakültesi, Radyasyon Onkolojisi Ana Bilim Dalı, Sivas, Türkiye)

Birsen YÜCEL (Sivas Cumhuriyet Üniversitesi, Tıp Fakültesi, Radyasyon Onkolojisi Ana Bilim Dalı, Sivas, Türkiye)

ENT Updates

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Yıl: 2020 Cilt: 10 Sayı: 1 Sayfa Aralığı: 271 - 277 Metin Dili: İngilizce DOI: 10.32448/entupdates.696940 İndeks Tarihi: 24-12-2020

Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers

Öz:

Introduction: In the present study, we aimed to evaluatethe relationship between neutrophil/lymphocyte ratio(NLR), platelet/lymphocyte ratio (PLR) and systemic immune inflammation index (SII) values and overall survival(OS) and disease-free survival (DFS) in patientsundergoing radiotherapy (RT) with a diagnosis of oralcavity cancer (OCC).Methods: 58 patients were included who were treatedwith a diagnosis of OCC who applied to Cumhuriyet University Faculty of Medicine Radiation Oncology Clinic between January 2009 and December 2018. Kaplan-Meieranalysis was used to determine OS and DFS. MultivariateCox regression analysis was also performed to detect independent prognostic factors.Results: All patients had a squamous cell carcinoma (SCC)of the oral cavity composed of 50 tongue SCC and 8 buccal SCC. Cut-off values in ROC analysis: 954 [Area=0.665(0.511-0.800), p=0.06] for SII, 174 [Area=0.659 (0.608-0.795), p<.001] for PLR and 3.2 [Area=0.699 (0.556-0.841),p=0.016] for NLR. Prognostic factors affecting OS wereSII, PLR, NLR and age. SII, NLR, PLR and grade were statistically significant prognostic factors for DFS. However, SIIwas an independent prognostic factor.Conclusion: In this study, high SII value was found to bean indicator of shorter OS and DFS in patients with OCC.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Olgu Sunumu Erişim Türü: Erişime Açık

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APA	erdiş e, Yücel B (2020). Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. , 271 - 277. 10.32448/entupdates.696940
Chicago	erdiş eda,Yücel Birsen Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. (2020): 271 - 277. 10.32448/entupdates.696940
MLA	erdiş eda,Yücel Birsen Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. , 2020, ss.271 - 277. 10.32448/entupdates.696940
AMA	erdiş e,Yücel B Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. . 2020; 271 - 277. 10.32448/entupdates.696940
Vancouver	erdiş e,Yücel B Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. . 2020; 271 - 277. 10.32448/entupdates.696940
IEEE	erdiş e,Yücel B "Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers." , ss.271 - 277, 2020. 10.32448/entupdates.696940
ISNAD	erdiş, eda - Yücel, Birsen. "Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers". (2020), 271-277. https://doi.org/10.32448/entupdates.696940

APA	erdiş e, Yücel B (2020). Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. ENT Updates, 10(1), 271 - 277. 10.32448/entupdates.696940
Chicago	erdiş eda,Yücel Birsen Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. ENT Updates 10, no.1 (2020): 271 - 277. 10.32448/entupdates.696940
MLA	erdiş eda,Yücel Birsen Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. ENT Updates, vol.10, no.1, 2020, ss.271 - 277. 10.32448/entupdates.696940
AMA	erdiş e,Yücel B Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. ENT Updates. 2020; 10(1): 271 - 277. 10.32448/entupdates.696940
Vancouver	erdiş e,Yücel B Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers. ENT Updates. 2020; 10(1): 271 - 277. 10.32448/entupdates.696940
IEEE	erdiş e,Yücel B "Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers." ENT Updates, 10, ss.271 - 277, 2020. 10.32448/entupdates.696940
ISNAD	erdiş, eda - Yücel, Birsen. "Prognostic Significance of Inflammatory Markers in Patients with Oral Cavity Cancers". ENT Updates 10/1 (2020), 271-277. https://doi.org/10.32448/entupdates.696940