Yıl: 2020 Cilt: 7 Sayı: 1 Sayfa Aralığı: 65 - 69 Metin Dili: İngilizce DOI: 10.34087/cbusbed.687605 İndeks Tarihi: 09-12-2020

The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B

Öz:
Objective: In this randomized study, we evaluated two different doses of intrathecal (IT) morphine with bupivacainefor analgesia after transurethral resection of bladder (TUR-B).Material and Method: Seventy-five patients were randomly divided into three groups. They were allocated to receiveIT morphine (100 µg) with 12.5 mg 0.5% bupivacaine (Group 1), IT morphine (200 µg) with 12.5 mg 0.5%bupivacaine (Group 2), and IT 12.5 mg 0.5% bupivacaine without morphine (Group 3). Postoperative pain wasevaluated by VAS during 24 h and each patient was given intravenous paracetamol and Dexketoprophen trometamolif pain severity was moderate.Results: VAS scores were significantly lower in Groups I and II than Group III at 1h, 2h, 4h, 6h, 12h (p< 0.05) (Figure1). The request for analgesia was significantly higher in Group III than the other two groups (p< 0.05). More patientsreported postoperative nausea in Group II than the other two groups (p< 0.05) (Figure 2).Conclusion: IT morphine (100 µg and 200 µg) with 12.5 mg 0.5% provided a significant reduction in postoperativepain scores compared to IT 12.5 mg 0.5% bupivacaine alone. IT morphine 100 µg provided comparable postoperativepain control with significantly lower side effects than IT morphine 200 µg after TUR-B.
Anahtar Kelime:

İntratekal Bupivakain İle Morfinin TUR-M Sonrası Postoperatif Analjeziye Etkisi

Öz:
Amaç: Bu randomize çalışmada transüretral mesane rezeksiyonu (TUR-M) sonrası analjezi için bupivakain ile iki farklı intratekal (IT) morfin dozu değerlendirildi. Gereç ve Yöntem: Yetmiş beş hasta rastgele üç gruba ayrıldı. IT morfin (100 ug) ile 12,5 mg %0,5 bupivakain (1. Grup), IT morfin (200 ug) ile 12,5 mg %0,5 bupivakain (2. Grup) ve morfinsiz IT 12,5 mg %0,5 bupivakain (3. Grup) alanlar olarak. Postoperatif ağrı 24 saat boyunca VAS ile değerlendirildi ve ağrı şiddeti orta derecede olan her hastaya intravenöz parasetamol ve Dexketoprophen trometamol verildi. Bulgular: Grup I ve II'de VAS skorları 1 saat, 2 saat, 4 saat, 6 saat, 12 saatte Grup III'e göre anlamlı olarak düşüktü (p<0.05). Analjezi talebi Grup III'te diğer iki gruba göre anlamlı derecede yüksekti (p< 0.05). Grup II'de postoperatif bulantı, diğer iki gruba göre daha fazla rapor edildi (p<0.05). Sonuç: IT %12,5 mg %0,5 bupivakain ile morfin (100 ug ve 200 ug), yanlız IT %12,5 mg %0,5 bupivakain’e kıyasla postoperatif ağrı skorlarında anlamlı bir azalma sağladı. TUR-M sonrasında postoperatif ağrı kontrolünde IT 100 ug morfin, IT 200 ug morfinden önemli ölçüde karşılaştırılabilir daha düşük yan etkiler sağladı.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA İncesu A, Deniz M, ERHAN E, Ugur G (2020). The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. , 65 - 69. 10.34087/cbusbed.687605
Chicago İncesu Aylin,Deniz Mustafa Nuri,ERHAN ELVAN,Ugur Gulden The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. (2020): 65 - 69. 10.34087/cbusbed.687605
MLA İncesu Aylin,Deniz Mustafa Nuri,ERHAN ELVAN,Ugur Gulden The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. , 2020, ss.65 - 69. 10.34087/cbusbed.687605
AMA İncesu A,Deniz M,ERHAN E,Ugur G The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. . 2020; 65 - 69. 10.34087/cbusbed.687605
Vancouver İncesu A,Deniz M,ERHAN E,Ugur G The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. . 2020; 65 - 69. 10.34087/cbusbed.687605
IEEE İncesu A,Deniz M,ERHAN E,Ugur G "The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B." , ss.65 - 69, 2020. 10.34087/cbusbed.687605
ISNAD İncesu, Aylin vd. "The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B". (2020), 65-69. https://doi.org/10.34087/cbusbed.687605
APA İncesu A, Deniz M, ERHAN E, Ugur G (2020). The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 7(1), 65 - 69. 10.34087/cbusbed.687605
Chicago İncesu Aylin,Deniz Mustafa Nuri,ERHAN ELVAN,Ugur Gulden The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7, no.1 (2020): 65 - 69. 10.34087/cbusbed.687605
MLA İncesu Aylin,Deniz Mustafa Nuri,ERHAN ELVAN,Ugur Gulden The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, vol.7, no.1, 2020, ss.65 - 69. 10.34087/cbusbed.687605
AMA İncesu A,Deniz M,ERHAN E,Ugur G The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2020; 7(1): 65 - 69. 10.34087/cbusbed.687605
Vancouver İncesu A,Deniz M,ERHAN E,Ugur G The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B. Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi. 2020; 7(1): 65 - 69. 10.34087/cbusbed.687605
IEEE İncesu A,Deniz M,ERHAN E,Ugur G "The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B." Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi, 7, ss.65 - 69, 2020. 10.34087/cbusbed.687605
ISNAD İncesu, Aylin vd. "The Efficacy of Intrathecal Morphine with Bupivacaine for Postoperative Analgesia After TUR-B". Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 7/1 (2020), 65-69. https://doi.org/10.34087/cbusbed.687605