Infertility causes many problems in biological, psychosocial, economic, ethical and cultural issues in individuals/couples. Infertility, which is a crisis situation, causes social isolation, stigmatization, deterioration in marital relations, psychological problems and stress. The use of some coping methods in the face of stress is accepted. Therefore, it is important to use effective coping methods to cope with infertility stress. In this systematic review, it was aimed to examine the results of the studies including individual coping methods used to cope with infertility stress. Inclusion criteria in systematic review; The purpose of this study is studying the individual coping methods with infertility stress, having a research paper [quantitative/qualitative], having a publication language in English and a research published in the last five years and also to be able to reach the full text and not to compile. Four of the sixteen studies that included the inclusion criteria in the review were descriptive, eight were cross-sectional descriptors, one was relational, one was qualitative, one was relational and one was qualitative, one was descriptive and one was in-depth interview design. When the studies are examined; infertile individuals used various methods of coping with stress. It has been concluded that attempts towards religion and spirituality, social isolation, ignoring the situation and attracting attention are the most commonly used methods. Health care providers should evaluate infertile individuals/couples with a holistic approach and should take an approach to help them cope with infertility stress.