HPV: Obvious but Not Necessary Cause of Cervical Cancer

Özkayalar, Hanife; Mocan, Gamze; SERAKINCI, Nedime; Tulay, Pinar

doi:10.5152/cjms.2020.963

HPV: Obvious but Not Necessary Cause of Cervical Cancer

Gamze MOCAN, (Yakın Doğu Üniversitesi, Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, Lefkoşa, Kıbrıs)

Pınar TÜLAY, (Yakın Doğu Üniversitesi, Tıp Fakültesi, Tıbbi Genetik Bölümü, Lefkoşa, Kıbrıs)

Hanife ÖZKAYALAR, (Yakın Doğu Üniversitesi, Tıp Fakültesi, Tıbbi Patoloji Anabilim Dalı, Lefkoşa, Kıbrıs)

Nedime SEKAKINCI (Yakın Doğu Üniversitesi, Tıp Fakültesi, Tıbbi Genetik Bölümü, Lefkoşa, Kıbrıs)

Cyprus Journal of Medical Sciences

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Yıl: 2020 Cilt: 5 Sayı: 2 Sayfa Aralığı: 107 - 112 Metin Dili: İngilizce DOI: 10.5152/cjms.2020.963 İndeks Tarihi: 10-12-2020

HPV: Obvious but Not Necessary Cause of Cervical Cancer

Öz:

BACKGROUND/AIMSCervical cancer is one of the most common cancers worldwide. Human papilomavirus (HPV) has been proposed to be one of the main players in the development of cervical cancer. The aim of this study was to investigate the association of HPV DNA and cervical cytology.MATERIAL and METHODSA total of 201 women undergoing routine gynaecological check up in Hospital were recruited. HPV genotyping and cervical Pap test were analysed.RESULTSOverall, 42% (85/201) of women analysed were tested positive for at least one of the HPV types tested. HPV DNA prevalence was the highest in women younger than 30 years old (59%, 50/85). Eighty four percent (71/85) of the HPV positive women had low to high grade cytological anomalies.CONCLUSIONThe presence of HPV DNA was strongly associated with the cytological anomalies, especially with specific HPV types. This study showed that detection of multiple HPV types is rather important in understanding the possible crosstalk among HPVs during the initiation and progression of cervical lesions. In conclusion, HPV still remains to be the most prevalent marker for cervical cancer and thus regular check up should be evaluated as a preventative policy for cervical cancer.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Mocan G, Tulay P, Özkayalar H, SERAKINCI N (2020). HPV: Obvious but Not Necessary Cause of Cervical Cancer. , 107 - 112. 10.5152/cjms.2020.963
Chicago	Mocan Gamze,Tulay Pinar,Özkayalar Hanife,SERAKINCI Nedime HPV: Obvious but Not Necessary Cause of Cervical Cancer. (2020): 107 - 112. 10.5152/cjms.2020.963
MLA	Mocan Gamze,Tulay Pinar,Özkayalar Hanife,SERAKINCI Nedime HPV: Obvious but Not Necessary Cause of Cervical Cancer. , 2020, ss.107 - 112. 10.5152/cjms.2020.963
AMA	Mocan G,Tulay P,Özkayalar H,SERAKINCI N HPV: Obvious but Not Necessary Cause of Cervical Cancer. . 2020; 107 - 112. 10.5152/cjms.2020.963
Vancouver	Mocan G,Tulay P,Özkayalar H,SERAKINCI N HPV: Obvious but Not Necessary Cause of Cervical Cancer. . 2020; 107 - 112. 10.5152/cjms.2020.963
IEEE	Mocan G,Tulay P,Özkayalar H,SERAKINCI N "HPV: Obvious but Not Necessary Cause of Cervical Cancer." , ss.107 - 112, 2020. 10.5152/cjms.2020.963
ISNAD	Mocan, Gamze vd. "HPV: Obvious but Not Necessary Cause of Cervical Cancer". (2020), 107-112. https://doi.org/10.5152/cjms.2020.963

APA	Mocan G, Tulay P, Özkayalar H, SERAKINCI N (2020). HPV: Obvious but Not Necessary Cause of Cervical Cancer. Cyprus Journal of Medical Sciences, 5(2), 107 - 112. 10.5152/cjms.2020.963
Chicago	Mocan Gamze,Tulay Pinar,Özkayalar Hanife,SERAKINCI Nedime HPV: Obvious but Not Necessary Cause of Cervical Cancer. Cyprus Journal of Medical Sciences 5, no.2 (2020): 107 - 112. 10.5152/cjms.2020.963
MLA	Mocan Gamze,Tulay Pinar,Özkayalar Hanife,SERAKINCI Nedime HPV: Obvious but Not Necessary Cause of Cervical Cancer. Cyprus Journal of Medical Sciences, vol.5, no.2, 2020, ss.107 - 112. 10.5152/cjms.2020.963
AMA	Mocan G,Tulay P,Özkayalar H,SERAKINCI N HPV: Obvious but Not Necessary Cause of Cervical Cancer. Cyprus Journal of Medical Sciences. 2020; 5(2): 107 - 112. 10.5152/cjms.2020.963
Vancouver	Mocan G,Tulay P,Özkayalar H,SERAKINCI N HPV: Obvious but Not Necessary Cause of Cervical Cancer. Cyprus Journal of Medical Sciences. 2020; 5(2): 107 - 112. 10.5152/cjms.2020.963
IEEE	Mocan G,Tulay P,Özkayalar H,SERAKINCI N "HPV: Obvious but Not Necessary Cause of Cervical Cancer." Cyprus Journal of Medical Sciences, 5, ss.107 - 112, 2020. 10.5152/cjms.2020.963
ISNAD	Mocan, Gamze vd. "HPV: Obvious but Not Necessary Cause of Cervical Cancer". Cyprus Journal of Medical Sciences 5/2 (2020), 107-112. https://doi.org/10.5152/cjms.2020.963