INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY

Koruyucu, Mine; Seymen, Figen; Kulekci, Guven; Topcuoglu, Nursen; Birant, Sinem

doi:10.7126/cumudj.624523

INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY

Mine KORUYUCU, (İstanbul Üniversitesi, Diş Hekimliği Fakültesi, Pedodonti Anabilim Dalı, İstanbul, Türkiye)

Sinem BİRANT, (Özel Muayenehane, İstanbul, Türkiye)

Emine Nursen TOPCUOĞLU, (İstanbul Üniversitesi, Diş Hekimliği Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Güven KÜLEKÇİ, (İstanbul Üniversitesi, Diş Hekimliği Fakültesi, Mikrobiyoloji Anabilim Dalı, İstanbul, Türkiye)

Figen SEYMEN (İstanbul Üniversitesi, Diş Hekimliği Fakültesi, Pedodonti Anabilim Dalı, İstanbul, Türkiye)

Cumhuriyet Dental Journal

1 0

Yıl: 2020 Cilt: 23 Sayı: 1 Sayfa Aralığı: 22 - 31 Metin Dili: İngilizce DOI: 10.7126/cumudj.624523 İndeks Tarihi: 17-12-2020

INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY

Öz:

Objectives: The purpose of this study is to compare the clinical, antibacterialand microbiological effects of the non-fluoride and fluoride toothpastes.Materials and Methods: In this study eighty children (3 to 12 years old)were randomly divided into four groups and followed for four weeks. Thefirst and second groups (40 children, 6-12 years) used different fluoridecontaining toothpastes; the third and fourth groups (40 children, 3-5 years)used non-fluoride toothpastes. The halitosis score, plaque index, gingivalindex, bleeding index, buffering capacities, Mutans Streptococci, Lactobacilliand yeast counts were recorded on 1st day, 7th day, 15th day and 30th day. Thefirst and second groups; the third and fourth groups were compared with eachother. Data were analyzed statistically by using Mann Whitney U tests,Wilcoxon Sign Test, Fisher Freeman Halton Exact Test and Mc Nemar Testwith a significance level of p<0.05.Results: Statistically significant association was not found in the mean scoresof halitosis, gingival index,plaque index, bleeding index, buffering capacity,Mutans Streptococci, Lactobacilli and yeast (p>0.05), between groupson thefirst day. All four toothpastes produced statistically significant reductionsfrom 1st day to 30th days in scores of halitosis, plaque index, gingival index,bleeding index and buffering capacity (p<0.01; p<0.05), within groups.Statistically significant reductions were found according to in MutansStreptococci, counts from 1st day to 30th day for group I, II and III (p<0.05);but was not found statistically significant changes in Group IV on the 30thdays (p>0.05).Conclusions: All tested toothpastes proved to be safe and significantlyeffective clinical and microbiological features.

Anahtar Kelime:

Farklı Diş Macunlarının Klinik ve Mikrobiyolojik Etkilerinin İncelenmesi: In Vivo Çalışma

Öz:

Amaç: Bu çalışmanın amacı, fluor içeren ve içermeyen diş macunlarının klinik, antibakteriyel ve mikrobiyolojik etkilerini karşılaştırmaktır. Gereç ve Yöntemler: Bu çalışmada 3-12 yaş arası 80 çocuk dört gruba ayrıldı ve dört hafta boyunca takip edildi. Birinci ve ikinci gruplar (40 çocuk, 6-12 yaş) farklı fluorlu diş macunları kullandı; üçüncü ve dördüncü gruplar (40 çocuk, 3-5 yaş) fluor içermeyen diş macunları kullandılar. Ağız kokusu skoru, plak indeksi, gingival indeks, kanama indeksi, tamponlama kapasiteleri, Mutans Streptokokları, Lactobacilli ve maya sayıları 1., 7., 15. ve 30. günde kaydedildi. Birinci ve ikinci grup; üçüncü ve dördüncü gruplar birbirleriyle karşılaştırıldı. Veriler istatistiksel olarak Mann Whitney U testi, Wilcoxon Sign Testi, Fisher Freeman Halton Exact Testi ve Mc Nemar Testi kullanılarak p<0,05 anlamlılık düzeyinde analiz edildi. Bulgular: İlk gün; gruplar arasında, ağız kokusu, gingival indeks, plak indeksi, kanama indeksi, tamponlama kapasitesi, S Mutans, Lactobacilli ve maya ortalamaları arasında istatistiksel olarak anlamlı ilişki bulunmadı (p>0,05). Dört diş macununun her biri, gruplar arasında, 1. günden 30. güne ağız kokusu, plak indeksi, gingival indeks, kanama indeksi ve tamponlama kapasitesi skorlarında istatistiksel olarak anlamlı azalma sağlamıştır (p<0,01; p<0,05). Grup I, II ve III’te; S. Mutans değerleri 1. günden 30. güne kadar istatistiksel olarak azalma gösterirken (p<0,05); Grup IV’te 30. günde istatisiksel olarak anlamlı bir değişiklik izlenmemiştir (p>0,05). Sonuç: Test edilen tüm diş macunları güvenli ve anlamlı derecede etkili klinik ve mikrobiyolojik özellikler göstermiştir.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik

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APA	Koruyucu M, Birant S, Topcuoglu N, Kulekci G, Seymen F (2020). INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. , 22 - 31. 10.7126/cumudj.624523
Chicago	Koruyucu Mine,Birant Sinem,Topcuoglu Nursen,Kulekci Guven,Seymen Figen INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. (2020): 22 - 31. 10.7126/cumudj.624523
MLA	Koruyucu Mine,Birant Sinem,Topcuoglu Nursen,Kulekci Guven,Seymen Figen INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. , 2020, ss.22 - 31. 10.7126/cumudj.624523
AMA	Koruyucu M,Birant S,Topcuoglu N,Kulekci G,Seymen F INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. . 2020; 22 - 31. 10.7126/cumudj.624523
Vancouver	Koruyucu M,Birant S,Topcuoglu N,Kulekci G,Seymen F INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. . 2020; 22 - 31. 10.7126/cumudj.624523
IEEE	Koruyucu M,Birant S,Topcuoglu N,Kulekci G,Seymen F "INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY." , ss.22 - 31, 2020. 10.7126/cumudj.624523
ISNAD	Koruyucu, Mine vd. "INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY". (2020), 22-31. https://doi.org/10.7126/cumudj.624523

APA	Koruyucu M, Birant S, Topcuoglu N, Kulekci G, Seymen F (2020). INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. Cumhuriyet Dental Journal , 23(1), 22 - 31. 10.7126/cumudj.624523
Chicago	Koruyucu Mine,Birant Sinem,Topcuoglu Nursen,Kulekci Guven,Seymen Figen INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. Cumhuriyet Dental Journal 23, no.1 (2020): 22 - 31. 10.7126/cumudj.624523
MLA	Koruyucu Mine,Birant Sinem,Topcuoglu Nursen,Kulekci Guven,Seymen Figen INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. Cumhuriyet Dental Journal , vol.23, no.1, 2020, ss.22 - 31. 10.7126/cumudj.624523
AMA	Koruyucu M,Birant S,Topcuoglu N,Kulekci G,Seymen F INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. Cumhuriyet Dental Journal . 2020; 23(1): 22 - 31. 10.7126/cumudj.624523
Vancouver	Koruyucu M,Birant S,Topcuoglu N,Kulekci G,Seymen F INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY. Cumhuriyet Dental Journal . 2020; 23(1): 22 - 31. 10.7126/cumudj.624523
IEEE	Koruyucu M,Birant S,Topcuoglu N,Kulekci G,Seymen F "INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY." Cumhuriyet Dental Journal , 23, ss.22 - 31, 2020. 10.7126/cumudj.624523
ISNAD	Koruyucu, Mine vd. "INVESTIGATION OF THE CLINICAL AND MICROBIOLOGICAL EFFECTS OF DIFFERENT TOOTHPASTES: IN-VIVOSTUDY". Cumhuriyet Dental Journal 23/1 (2020), 22-31. https://doi.org/10.7126/cumudj.624523