SARS-CoV-2 is a single-stranded RNA spherical virus spikes formed by glycoproteins. The leading cause of death was linked toacute respiratory distress syndrome, myocardial injury, or renal failure. After the first case reported on the 11th of March in TurkeyMinistry of Health and Interior declared some regulations on the public, such as travel restrictions, traffic restrictions, social distancinghomes, and centralized quarantine. Although chemotherapy adherence is a highly studied area for both oral and intravenous agentsin cancer patients, no available data exist in a pandemic world with many social restrictions. The records of patients who have activecancer treatment in the department of medical oncology retrospectively analyzed. The age, gender, diagnosis, chemotherapy type,rendezvous, and coming dates recorded. Four chemotherapy delays (3.7%) were observed out of 52 patients before the 11th ofMarch 2020, while 43 chemotherapy delays (39,8%9) occurred out of 107 patients after the first COVID-19 case and the restrictionsin Turkey. Twenty patients had treatment delay without reason and did not show up for treatment on the day of chemotherapy. Thetreatment delays without reasons are significantly different in the pre and post COVID-19 pandemic era. The hematologic toxicity rateswere similar when compared pre and post COVID-19 period. The non-specific regulations and declarations confuse the patients andprevent them from reaching the treatment which is needed. In the case of pandemic regulations, oncologic patients may have specialconsiderations for government decisions.