The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy

Sakar, Mehmet Nafi; tahaoglu, ali emre; budak, mehmet şükrü; Akay, Emrullah; Güngör, Sinan; SARIDAS DEMIR, SUREYYA; Demir, Bulent; Balsak, Deniz

doi:10.21613/GORM.2019.942

The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy

Mehmet Nafi SAKAR, (Memorial Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, Diyarbakır, Türkiye)

Deniz BALSAK, (Haliç Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul, Türkiye)

Süreyya DEMİR, (Dokuz Eylül Üniversitesi, Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul, Türkiye)

Mehmet Sukru BUDAK, (Sağlık Bilimleri Üniversitesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Gazi Yaşargil Eğitimi ve Araştırma Hastanesi, Diyarbakır, Türkiye)

Ali Emre TAHAOĞLU, (Sağlık Bilimleri Üniversitesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Gazi Yaşargil Eğitimi ve Araştırma Hastanesi, Diyarbakır, Türkiye)

Sinan Emre GÜNGÖR, (Süleymaniye Eğitimi ve Sağlık Bilimleri Üniversitesi, Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul, Türkiye)

Emrullah AKAY, (Süleymaniye Eğitimi ve Sağlık Bilimleri Üniversitesi, Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, İstanbul, Türkiye)

Bülent DEMİR (Girilmemişş)

GORM:Gynecology Obstetrics & Reproductive Medicine

3 0

Yıl: 2020 Cilt: 26 Sayı: 1 Sayfa Aralığı: 1 - 5 Metin Dili: İngilizce DOI: 10.21613/GORM.2019.942 İndeks Tarihi: 18-12-2020

The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy

Öz:

OBJECTIVE: There are cases where ultrasonographic evaluation is inadequate in determining firsttrimesterhealthy pregnancy. In these cases, both the patient and the clinician are involved in a worryingexpectation. The single serum progesterone measurement was tried to predict pregnancy prognosisin short time period. This study evaluated the predictive value of a single serum progesterone measurementin first-trimester pregnancy loss.STUDY DESIGN: A prospective case-control study was conducted between July 2013 and July 2014 inTertiary Hospital. The study compared 106 patients with threatened abortion (vaginal bleeding or spotting)before 13 weeks of gestation with 110 healthy control pregnancies. Samples of serum progesteronewere obtained on the day each patient was admitted to the hospital. A Beckman-Coulter macro-Enzymelinkedimmunoassay (ELISA) system was used to measure serum levels of progesterone (Beckman-Coulter, Ireland).RESULTS: Progesterone levels were measured when the patients first visited the hospital and theywere followed until the end of the first trimester. Progesterone levels differed significantly (p=0.013) betweenthe two groups. The spontaneous abortion rate was significantly (p=0.044) higher in the casegroup. Progesterone levels differed significantly (p=0.001) between ongoing pregnancy and spontaneousabortion groups. Using a cut-off level of 10.7 ng/mL, the sensitivity, specificity, and positive andnegative predictive values were 92.1%, 44%, 92.6%, and 42.3%, respectively, for viable pregnancies.CONCLUSION: A single measurement of progesterone levels in serum can predict the prognosis of aviable first-trimester pregnancy, while it is less effective for identifying non-viable pregnancies.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Sakar M, Balsak D, SARIDAS DEMIR S, budak m, tahaoglu a, Güngör S, Akay E, Demir B (2020). The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. , 1 - 5. 10.21613/GORM.2019.942
Chicago	Sakar Mehmet Nafi,Balsak Deniz,SARIDAS DEMIR SUREYYA,budak mehmet şükrü,tahaoglu ali emre,Güngör Sinan,Akay Emrullah,Demir Bulent The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. (2020): 1 - 5. 10.21613/GORM.2019.942
MLA	Sakar Mehmet Nafi,Balsak Deniz,SARIDAS DEMIR SUREYYA,budak mehmet şükrü,tahaoglu ali emre,Güngör Sinan,Akay Emrullah,Demir Bulent The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. , 2020, ss.1 - 5. 10.21613/GORM.2019.942
AMA	Sakar M,Balsak D,SARIDAS DEMIR S,budak m,tahaoglu a,Güngör S,Akay E,Demir B The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. . 2020; 1 - 5. 10.21613/GORM.2019.942
Vancouver	Sakar M,Balsak D,SARIDAS DEMIR S,budak m,tahaoglu a,Güngör S,Akay E,Demir B The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. . 2020; 1 - 5. 10.21613/GORM.2019.942
IEEE	Sakar M,Balsak D,SARIDAS DEMIR S,budak m,tahaoglu a,Güngör S,Akay E,Demir B "The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy." , ss.1 - 5, 2020. 10.21613/GORM.2019.942
ISNAD	Sakar, Mehmet Nafi vd. "The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy". (2020), 1-5. https://doi.org/10.21613/GORM.2019.942

APA	Sakar M, Balsak D, SARIDAS DEMIR S, budak m, tahaoglu a, Güngör S, Akay E, Demir B (2020). The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. GORM:Gynecology Obstetrics & Reproductive Medicine, 26(1), 1 - 5. 10.21613/GORM.2019.942
Chicago	Sakar Mehmet Nafi,Balsak Deniz,SARIDAS DEMIR SUREYYA,budak mehmet şükrü,tahaoglu ali emre,Güngör Sinan,Akay Emrullah,Demir Bulent The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. GORM:Gynecology Obstetrics & Reproductive Medicine 26, no.1 (2020): 1 - 5. 10.21613/GORM.2019.942
MLA	Sakar Mehmet Nafi,Balsak Deniz,SARIDAS DEMIR SUREYYA,budak mehmet şükrü,tahaoglu ali emre,Güngör Sinan,Akay Emrullah,Demir Bulent The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. GORM:Gynecology Obstetrics & Reproductive Medicine, vol.26, no.1, 2020, ss.1 - 5. 10.21613/GORM.2019.942
AMA	Sakar M,Balsak D,SARIDAS DEMIR S,budak m,tahaoglu a,Güngör S,Akay E,Demir B The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. GORM:Gynecology Obstetrics & Reproductive Medicine. 2020; 26(1): 1 - 5. 10.21613/GORM.2019.942
Vancouver	Sakar M,Balsak D,SARIDAS DEMIR S,budak m,tahaoglu a,Güngör S,Akay E,Demir B The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy. GORM:Gynecology Obstetrics & Reproductive Medicine. 2020; 26(1): 1 - 5. 10.21613/GORM.2019.942
IEEE	Sakar M,Balsak D,SARIDAS DEMIR S,budak m,tahaoglu a,Güngör S,Akay E,Demir B "The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy." GORM:Gynecology Obstetrics & Reproductive Medicine, 26, ss.1 - 5, 2020. 10.21613/GORM.2019.942
ISNAD	Sakar, Mehmet Nafi vd. "The Ability of a Single Serum Progesterone Measurement to Predict the Prognosis of First Trimester Pregnancy". GORM:Gynecology Obstetrics & Reproductive Medicine 26/1 (2020), 1-5. https://doi.org/10.21613/GORM.2019.942