Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions

COLAK, RUYA; Gokmen Yildirim, Tulin; Calkavur, Sebnem; Alkan Özdemir, Senem; KULALI, Ferit; yangın ergon, ezgi

doi:10.21613/GORM.2019.994

Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions

Şebnem ÇALKAVUR, (Dr.Behçet Uz Çocuk Hastalığı ve Çocuk Cerrahisi Eğitim ve Araştırma Hastanesi, Neonatoloji Anabilim Dalı, İzmir, Türkiye)

Senem ALKAN ÖZDEMİR, (Dr.Behçet Uz Çocuk Hastalığı ve Çocuk Cerrahisi Eğitim ve Araştırma Hastanesi, Neonatoloji Anabilim Dalı, İzmir, Türkiye)

Rüya ÇOLAK, (Dr.Behçet Uz Çocuk Hastalığı ve Çocuk Cerrahisi Eğitim ve Araştırma Hastanesi, Neonatoloji Anabilim Dalı, İzmir, Türkiye)

Ezgi YANGIN ERGON, (Dr.Behçet Uz Çocuk Hastalığı ve Çocuk Cerrahisi Eğitim ve Araştırma Hastanesi, Neonatoloji Anabilim Dalı, İzmir, Türkiye)

Ferit KULALI, (Dr.Behçet Uz Çocuk Hastalığı ve Çocuk Cerrahisi Eğitim ve Araştırma Hastanesi, Neonatoloji Anabilim Dalı, İzmir, Türkiye)

Tülin GÖKMEN YILDIRIM (Dr.Behçet Uz Çocuk Hastalığı ve Çocuk Cerrahisi Eğitim ve Araştırma Hastanesi, Neonatoloji Anabilim Dalı, İzmir, Türkiye)

GORM:Gynecology Obstetrics & Reproductive Medicine

3 0

Yıl: 2020 Cilt: 26 Sayı: 1 Sayfa Aralığı: 64 - 69 Metin Dili: İngilizce DOI: 10.21613/GORM.2019.994 İndeks Tarihi: 18-12-2020

Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions

Öz:

OBJECTIVE: We aimed to investigate the role of incomplete of antenatal steroid therapy by comparingwith no and complete steroid exposure on mortality and morbidity in preterm infants.STUDY DESIGN: This is a prospective, an observational study which includes preterm infants of 32weeks of gestation and/or ≤1500 grams who were referred to Izmir Dr. Behcet Uz Children’s HospitalNICU during the one year period. Infants were divided into three groups according to the administrationof antenatal steroid as those who received incomplete-dose antenatal steroid, complete dose steroidtherapy and those with no steroid exposure. Intubation at the delivery room, surfactant requirement, theinotropic requirement in the first 72 hours and morbidities associated with prematurity were determinedas the primary results. Mortality and bronchopulmonary dysplasia at discharge and stage ≥2 retinopathywere analyzed as secondary outcomes.RESULTS: We found that 54 infants were born with an incomplete dose, 55 infants with complete doseand 38 infants with no steroid therapy. Surfactant requirement, inotropic requirement, and hemodynamicallysignificant patent ductus arteriosus were lower in the steroid exposure group leading to a statisticaldifference (p <0.05). Also, it was found that mortality and Bronchopulmonary dysplasia was lower inthe incomplete and complete dose steroid groups, leading to a statistical difference (p <0.05).CONCLUSION: We speculate that even incomplete dose steroid may reduce mortality by reducing respiratorydistress syndrome.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Calkavur S, Alkan Özdemir S, COLAK R, yangın ergon e, KULALI F, Gokmen Yildirim T (2020). Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. , 64 - 69. 10.21613/GORM.2019.994
Chicago	Calkavur Sebnem,Alkan Özdemir Senem,COLAK RUYA,yangın ergon ezgi,KULALI Ferit,Gokmen Yildirim Tulin Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. (2020): 64 - 69. 10.21613/GORM.2019.994
MLA	Calkavur Sebnem,Alkan Özdemir Senem,COLAK RUYA,yangın ergon ezgi,KULALI Ferit,Gokmen Yildirim Tulin Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. , 2020, ss.64 - 69. 10.21613/GORM.2019.994
AMA	Calkavur S,Alkan Özdemir S,COLAK R,yangın ergon e,KULALI F,Gokmen Yildirim T Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. . 2020; 64 - 69. 10.21613/GORM.2019.994
Vancouver	Calkavur S,Alkan Özdemir S,COLAK R,yangın ergon e,KULALI F,Gokmen Yildirim T Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. . 2020; 64 - 69. 10.21613/GORM.2019.994
IEEE	Calkavur S,Alkan Özdemir S,COLAK R,yangın ergon e,KULALI F,Gokmen Yildirim T "Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions." , ss.64 - 69, 2020. 10.21613/GORM.2019.994
ISNAD	Calkavur, Sebnem vd. "Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions". (2020), 64-69. https://doi.org/10.21613/GORM.2019.994

APA	Calkavur S, Alkan Özdemir S, COLAK R, yangın ergon e, KULALI F, Gokmen Yildirim T (2020). Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. GORM:Gynecology Obstetrics & Reproductive Medicine, 26(1), 64 - 69. 10.21613/GORM.2019.994
Chicago	Calkavur Sebnem,Alkan Özdemir Senem,COLAK RUYA,yangın ergon ezgi,KULALI Ferit,Gokmen Yildirim Tulin Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. GORM:Gynecology Obstetrics & Reproductive Medicine 26, no.1 (2020): 64 - 69. 10.21613/GORM.2019.994
MLA	Calkavur Sebnem,Alkan Özdemir Senem,COLAK RUYA,yangın ergon ezgi,KULALI Ferit,Gokmen Yildirim Tulin Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. GORM:Gynecology Obstetrics & Reproductive Medicine, vol.26, no.1, 2020, ss.64 - 69. 10.21613/GORM.2019.994
AMA	Calkavur S,Alkan Özdemir S,COLAK R,yangın ergon e,KULALI F,Gokmen Yildirim T Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. GORM:Gynecology Obstetrics & Reproductive Medicine. 2020; 26(1): 64 - 69. 10.21613/GORM.2019.994
Vancouver	Calkavur S,Alkan Özdemir S,COLAK R,yangın ergon e,KULALI F,Gokmen Yildirim T Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions. GORM:Gynecology Obstetrics & Reproductive Medicine. 2020; 26(1): 64 - 69. 10.21613/GORM.2019.994
IEEE	Calkavur S,Alkan Özdemir S,COLAK R,yangın ergon e,KULALI F,Gokmen Yildirim T "Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions." GORM:Gynecology Obstetrics & Reproductive Medicine, 26, ss.64 - 69, 2020. 10.21613/GORM.2019.994
ISNAD	Calkavur, Sebnem vd. "Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions". GORM:Gynecology Obstetrics & Reproductive Medicine 26/1 (2020), 64-69. https://doi.org/10.21613/GORM.2019.994