Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial

Kadiroğulları, Pınar; Gonen, Songul Ece; Seckin, Kerem Doga; Börekçi, Bünyamin

doi:10.201613/GORM.2019.872

Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial

Songül Ece GÖNEN, (İstanbul Sağlık Bilimleri Üniversitesi, Kanuni Sultan Süleyman Araştırması ve Eğitim Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye)

Pınar KADİROĞULLARI, (İstanbul Sağlık Bilimleri Üniversitesi, Kanuni Sultan Süleyman Araştırması ve Eğitim Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye)

Kerem SEÇKİN, (İstanbul Sağlık Bilimleri Üniversitesi, Kanuni Sultan Süleyman Araştırması ve Eğitim Hastanesi, Kadın Hastalıkları ve Doğum Kliniği, İstanbul, Türkiye)

Bünyamin BÖREKÇİ (Erzurum Atatürk Üniversitesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Erzurum, Türkiye)

GORM:Gynecology Obstetrics & Reproductive Medicine

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Yıl: 2020 Cilt: 26 Sayı: 1 Sayfa Aralığı: 38 - 43 Metin Dili: İngilizce DOI: 10.201613/GORM.2019.872 İndeks Tarihi: 18-12-2020

Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial

Öz:

OBJECTIVE: We aimed to investigate the effect of acupuncture performed as an adjuvant therapy to invitro fertilization, on pregnancy rates by performing acupuncture on the day of embryo transfer, one hourbefore the procedure and one hour after the procedure.STUDY DESIGN: In this open-label randomized prospective controlled study, 60 unexplained infertilitypatients enrolled for in vitro fertilization treatment were randomized by a computer-based number generatorfor acupuncture performance and no-treatment. All patients received rFSH (Gonal-F®) for ovulationinduction and the antagonist Cetrorelix (Cetrotide®) to prevent premature ovulation. Ovulation wastriggered by using hCG (Ovitrelle®) and egg collection was done after 36-48 hours. In the study group,acupuncture was performed by intradermal needling, bilaterally with a sterile needle, both one hour beforeand one hour after the embryo transfer. Acupuncture was not performed on the control group. Theresults of the treatment were evaluated 12 days after embryo transfer.RESULTS: Thirty patients were randomized into the study group and 30 patients were randomly placedin the control group. Although there was no statistically significant difference between groups in terms ofβ-hCG positivity, it was 43.3% in the study group and 36.7% in the control group (p>0.05).CONCLUSION: The success rate of in vitro fertilization was higher in terms of pregnancy rate in the patientgroup who received acupuncture procedure as well, but the difference was not statistically significant.This may be due to the type of acupuncture procedure selected or insufficient sample size. As aresult, further studies involving larger numbers of participants and using different acupuncture techniquesare needed.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Gonen S, Kadiroğulları P, Seckin K, Börekçi B (2020). Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. , 38 - 43. 10.201613/GORM.2019.872
Chicago	Gonen Songul Ece,Kadiroğulları Pınar,Seckin Kerem Doga,Börekçi Bünyamin Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. (2020): 38 - 43. 10.201613/GORM.2019.872
MLA	Gonen Songul Ece,Kadiroğulları Pınar,Seckin Kerem Doga,Börekçi Bünyamin Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. , 2020, ss.38 - 43. 10.201613/GORM.2019.872
AMA	Gonen S,Kadiroğulları P,Seckin K,Börekçi B Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. . 2020; 38 - 43. 10.201613/GORM.2019.872
Vancouver	Gonen S,Kadiroğulları P,Seckin K,Börekçi B Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. . 2020; 38 - 43. 10.201613/GORM.2019.872
IEEE	Gonen S,Kadiroğulları P,Seckin K,Börekçi B "Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial." , ss.38 - 43, 2020. 10.201613/GORM.2019.872
ISNAD	Gonen, Songul Ece vd. "Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial". (2020), 38-43. https://doi.org/10.201613/GORM.2019.872

APA	Gonen S, Kadiroğulları P, Seckin K, Börekçi B (2020). Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. GORM:Gynecology Obstetrics & Reproductive Medicine, 26(1), 38 - 43. 10.201613/GORM.2019.872
Chicago	Gonen Songul Ece,Kadiroğulları Pınar,Seckin Kerem Doga,Börekçi Bünyamin Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. GORM:Gynecology Obstetrics & Reproductive Medicine 26, no.1 (2020): 38 - 43. 10.201613/GORM.2019.872
MLA	Gonen Songul Ece,Kadiroğulları Pınar,Seckin Kerem Doga,Börekçi Bünyamin Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. GORM:Gynecology Obstetrics & Reproductive Medicine, vol.26, no.1, 2020, ss.38 - 43. 10.201613/GORM.2019.872
AMA	Gonen S,Kadiroğulları P,Seckin K,Börekçi B Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. GORM:Gynecology Obstetrics & Reproductive Medicine. 2020; 26(1): 38 - 43. 10.201613/GORM.2019.872
Vancouver	Gonen S,Kadiroğulları P,Seckin K,Börekçi B Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial. GORM:Gynecology Obstetrics & Reproductive Medicine. 2020; 26(1): 38 - 43. 10.201613/GORM.2019.872
IEEE	Gonen S,Kadiroğulları P,Seckin K,Börekçi B "Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial." GORM:Gynecology Obstetrics & Reproductive Medicine, 26, ss.38 - 43, 2020. 10.201613/GORM.2019.872
ISNAD	Gonen, Songul Ece vd. "Does Acupuncture Have Any Benefit in the IVF Treatment of Couples with Unexplained Infertility; A Prospective Randomized Controlled Trial". GORM:Gynecology Obstetrics & Reproductive Medicine 26/1 (2020), 38-43. https://doi.org/10.201613/GORM.2019.872