Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy

Soydemir, Gülşen Pınar; Ozer, elif eda

doi:10.5505/tjo.2020.2275

Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy

Gülşen Pınar SOYDEMİR GÖÇER, (Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Kliniği, İstanbul, Türkiye)

Elif Eda OZER (Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Kliniği, İstanbul, Türkiye)

Türk Onkoloji Dergisi

1 0

Yıl: 2020 Cilt: 35 Sayı: 3 Sayfa Aralığı: 266 - 273 Metin Dili: İngilizce DOI: 10.5505/tjo.2020.2275 İndeks Tarihi: 26-11-2020

Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy

Öz:

OBJECTIVERadiation-induced hearing loss is a common complication of radiotherapy in patients with brain tumors.This retrospective study aims to compare Intensity-Modulated Radiotherapy (IMRT) with VolumetricModulated Arc Therapy (VMAT) for the patients with brain tumor concerning the sparing effecton the cochlea by comparing dosimetric parameters.METHODSIn this study, 20 patients with pathological grade IV brain tumors were selected to have planning withVMAT and IMRT for dosimetric comparison concerning organs at risk. Target coverage and dose homogeneitywere evaluated by calculating the conformity index (CI) and homogeneity index (HI) values.The treatment plans were accepted only if they met the set of planning objectives defined in the protocol.RESULTSThe homogeneity and conformity of the two plans were statistically similar. The dose to receive 95%(D95%) of planning target volume (PTV) and the minimum dose received 46 Gy (Dmin) were significantlylower with IMRT compared with VMAT (p=0.01 and 0.001, respectively), but the volume receiving 46Gy (V46Gy) and 60 Gy (V60Gy), and D95%, Dmean, Dmax, Dmin received 60 Gy were not different between twomethods. There was no significant difference in D95%, Dmean, and Dmax for total and contralateral cochleaeamong groups.CONCLUSIONSince VMAT and IMRT planning have the same effect on sparing the cochlea; no superiority can be suggestedamong these two plans during radiotherapy. The choice of plan for the treatment of brain tumorsappears to base on the clinical experience, especially for patients who may experience hearing loss.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Soydemir G, Ozer e (2020). Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. , 266 - 273. 10.5505/tjo.2020.2275
Chicago	Soydemir Gülşen Pınar,Ozer elif eda Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. (2020): 266 - 273. 10.5505/tjo.2020.2275
MLA	Soydemir Gülşen Pınar,Ozer elif eda Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. , 2020, ss.266 - 273. 10.5505/tjo.2020.2275
AMA	Soydemir G,Ozer e Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. . 2020; 266 - 273. 10.5505/tjo.2020.2275
Vancouver	Soydemir G,Ozer e Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. . 2020; 266 - 273. 10.5505/tjo.2020.2275
IEEE	Soydemir G,Ozer e "Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy." , ss.266 - 273, 2020. 10.5505/tjo.2020.2275
ISNAD	Soydemir, Gülşen Pınar - Ozer, elif eda. "Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy". (2020), 266-273. https://doi.org/10.5505/tjo.2020.2275

APA	Soydemir G, Ozer e (2020). Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. Türk Onkoloji Dergisi, 35(3), 266 - 273. 10.5505/tjo.2020.2275
Chicago	Soydemir Gülşen Pınar,Ozer elif eda Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. Türk Onkoloji Dergisi 35, no.3 (2020): 266 - 273. 10.5505/tjo.2020.2275
MLA	Soydemir Gülşen Pınar,Ozer elif eda Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. Türk Onkoloji Dergisi, vol.35, no.3, 2020, ss.266 - 273. 10.5505/tjo.2020.2275
AMA	Soydemir G,Ozer e Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. Türk Onkoloji Dergisi. 2020; 35(3): 266 - 273. 10.5505/tjo.2020.2275
Vancouver	Soydemir G,Ozer e Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy. Türk Onkoloji Dergisi. 2020; 35(3): 266 - 273. 10.5505/tjo.2020.2275
IEEE	Soydemir G,Ozer e "Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy." Türk Onkoloji Dergisi, 35, ss.266 - 273, 2020. 10.5505/tjo.2020.2275
ISNAD	Soydemir, Gülşen Pınar - Ozer, elif eda. "Cochlear Sparing for Brain Tumor Radiotherapy: A Retrospective Study Comparing Intensity-Modulated Radiotherapy and Volumetric Modulated Arc Therapy". Türk Onkoloji Dergisi 35/3 (2020), 266-273. https://doi.org/10.5505/tjo.2020.2275