Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience

Nazlı, Mehmet Ali; Can Trabulus, Didem; Mermut, Özlem; ARSLAN, ESRA

doi:10.5505/tjo.2020.2278

Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience

Özlem MERMUT, (Sağlık Bilimleri Üniversitesi, İstanbul Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Anabilim Dalı, İstanbul, Türkiye)

Didem Can TRABLUS, (Sağlık Bilimleri Üniversitesi, İstanbul Eğitim ve Araştırma Hastanesi, Genel Cerrahi Kliniği, İstanbul, Türkiye)

Esra ARSLAN, (Sağlık Bilimleri Üniversitesi, İstanbul Eğitim ve Araştırma Hastanesi, Nükleer Tıp Kliniği, İstanbul, Türkiye)

Mehmet Ali NAZLI (Sağlık Bilimleri Üniversitesi, İstanbul Eğitim ve Araştırma Hastanesi, Radyoloji Bölümü, İstanbul, Türkiye)

Türk Onkoloji Dergisi

5 0

Yıl: 2020 Cilt: 35 Sayı: 3 Sayfa Aralığı: 327 - 333 Metin Dili: İngilizce DOI: 10.5505/tjo.2020.2278 İndeks Tarihi: 26-11-2020

Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience

Öz:

OBJECTIVEOligometastatic tumors are usually characterized by a solitary or small number of metastatic lesionsconfined to a single organ. This study aims to investigate the prognostic factors for overall survival inpatients with extracranial oligometastatic breast cancer and share our own experiences.METHODSWe evaluated 130 patients who were admitted for the diagnosis of extracranial oligometastatic breastcancer at the University of Health Sciences Istanbul Training and Research Hospital Department ofRadiation Oncology between 2013 and 2017.RESULTSAge (p=0.003), type of surgery (p<0.001), estrogen receptor status positivity (p=0.011), location of metastasis(p<0.001), premenopausal status (p=0.001), number of metastases (p=0.029), administration ofchemotherapy (p<0.001) and application of curative radiotherapy (p<0.001) were the prognostic factorsaffecting overall survival in univariate analysis. Age<50 (HR: 5.434; 95% CI: 1.025-28.80; p=0.047), onlybone metastasis (HR: 0.165; 95% CI: 0.073–0.370; p<0.001), premenopausal status (HR: 0.125; 95% CI:0.022–0.723; p=0.020) and chemotherapy administration (HR: 4.342; 95% CI: 1.792–10.52; p=0.001)were independent prognostic factors that positively affected overall survival in multivariate analysis.CONCLUSIONOligometastatic breast cancer is a separate subgroup with long-term prognosis for patients with metastaticbreast cancer. In patients with extracranial oligometastatic breast cancer, long-term disease controlmay be possible using more aggressive multidisciplinary treatments, particularly in patients withbone-only metastases.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	Mermut Ö, Can Trabulus D, ARSLAN E, Nazlı M (2020). Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. , 327 - 333. 10.5505/tjo.2020.2278
Chicago	Mermut Özlem,Can Trabulus Didem,ARSLAN ESRA,Nazlı Mehmet Ali Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. (2020): 327 - 333. 10.5505/tjo.2020.2278
MLA	Mermut Özlem,Can Trabulus Didem,ARSLAN ESRA,Nazlı Mehmet Ali Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. , 2020, ss.327 - 333. 10.5505/tjo.2020.2278
AMA	Mermut Ö,Can Trabulus D,ARSLAN E,Nazlı M Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. . 2020; 327 - 333. 10.5505/tjo.2020.2278
Vancouver	Mermut Ö,Can Trabulus D,ARSLAN E,Nazlı M Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. . 2020; 327 - 333. 10.5505/tjo.2020.2278
IEEE	Mermut Ö,Can Trabulus D,ARSLAN E,Nazlı M "Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience." , ss.327 - 333, 2020. 10.5505/tjo.2020.2278
ISNAD	Mermut, Özlem vd. "Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience". (2020), 327-333. https://doi.org/10.5505/tjo.2020.2278

APA	Mermut Ö, Can Trabulus D, ARSLAN E, Nazlı M (2020). Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. Türk Onkoloji Dergisi, 35(3), 327 - 333. 10.5505/tjo.2020.2278
Chicago	Mermut Özlem,Can Trabulus Didem,ARSLAN ESRA,Nazlı Mehmet Ali Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. Türk Onkoloji Dergisi 35, no.3 (2020): 327 - 333. 10.5505/tjo.2020.2278
MLA	Mermut Özlem,Can Trabulus Didem,ARSLAN ESRA,Nazlı Mehmet Ali Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. Türk Onkoloji Dergisi, vol.35, no.3, 2020, ss.327 - 333. 10.5505/tjo.2020.2278
AMA	Mermut Ö,Can Trabulus D,ARSLAN E,Nazlı M Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. Türk Onkoloji Dergisi. 2020; 35(3): 327 - 333. 10.5505/tjo.2020.2278
Vancouver	Mermut Ö,Can Trabulus D,ARSLAN E,Nazlı M Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience. Türk Onkoloji Dergisi. 2020; 35(3): 327 - 333. 10.5505/tjo.2020.2278
IEEE	Mermut Ö,Can Trabulus D,ARSLAN E,Nazlı M "Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience." Türk Onkoloji Dergisi, 35, ss.327 - 333, 2020. 10.5505/tjo.2020.2278
ISNAD	Mermut, Özlem vd. "Survival and Treatment Outcomes in Patients with Extracranial Oligometastatic Breast Cancer: Single-Center Experience". Türk Onkoloji Dergisi 35/3 (2020), 327-333. https://doi.org/10.5505/tjo.2020.2278