Binary grading may be more appropriate for endometrial cancer

Objective: To elucidate the survival consequences of the prognostic factors for endometrial cancer.Material and Methods: This was a retrospective study of 276 patients diagnosed with endometrial cancer who admitted for staging surgery.The extent of the surgery was determined by clinical staging and preoperative evaluation. The pathology specimens were reassessed by agynecopathologist. Independent risk factors were revealed for the progression-free survival (PFS), overall survival (OS) and disease-specificsurvival (DSS) utilizing Kaplan-Meier and “Cox” proportional analysis.Results: The median follow up of the patients was 50 months. Of the 29 patients who died, 15 (5.43%) died because of endometrial cancer.Multivariate analysis revealed that independent risk factors for OS and PFS were stage (p=0.002, 0.002, respectively) and grade 3 (G3) histology(p=0.013, 0.015, respectively). Positive peritoneal cytology was an independent risk factor for OS (p=0.024), but not for PFS (p=0.050). Stage(p=0.005) was found to be the only independent risk factor for DSS. Patients with G1 and G2 histology had a similar and more favorable prognosisthan patients with G3 histology.Conclusion: Advanced stage, high-grade tumor and the presence of positive peritoneal cytology were ascertained as independent prognosticfactors for endometrial cancer. A binary histological grading system could be simpler and as effective as the current three grade system becausegrade 1 and 2 patients showed similar prognosis. (J Turk Ger Gynecol Assoc 2020; 21: 163-70)

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APA	Koyuncu K, Altın D, Turgay B, Varli B, Konuralp Atakul B, Şükür Y, Taşkın S, ortaç f (2020). Binary grading may be more appropriate for endometrial cancer. , 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
Chicago	Koyuncu Kazibe,Altın Duygu,Turgay Batuhan,Varli Bulut,Konuralp Atakul Bahar,Şükür Yavuz Emre,Taşkın Salih,ortaç fırat Binary grading may be more appropriate for endometrial cancer. (2020): 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
MLA	Koyuncu Kazibe,Altın Duygu,Turgay Batuhan,Varli Bulut,Konuralp Atakul Bahar,Şükür Yavuz Emre,Taşkın Salih,ortaç fırat Binary grading may be more appropriate for endometrial cancer. , 2020, ss.163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
AMA	Koyuncu K,Altın D,Turgay B,Varli B,Konuralp Atakul B,Şükür Y,Taşkın S,ortaç f Binary grading may be more appropriate for endometrial cancer. . 2020; 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
Vancouver	Koyuncu K,Altın D,Turgay B,Varli B,Konuralp Atakul B,Şükür Y,Taşkın S,ortaç f Binary grading may be more appropriate for endometrial cancer. . 2020; 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
IEEE	Koyuncu K,Altın D,Turgay B,Varli B,Konuralp Atakul B,Şükür Y,Taşkın S,ortaç f "Binary grading may be more appropriate for endometrial cancer." , ss.163 - 170, 2020. 10.4274/jtgga.galenos.2019.2019.0068
ISNAD	Koyuncu, Kazibe vd. "Binary grading may be more appropriate for endometrial cancer". (2020), 163-170. https://doi.org/10.4274/jtgga.galenos.2019.2019.0068

APA	Koyuncu K, Altın D, Turgay B, Varli B, Konuralp Atakul B, Şükür Y, Taşkın S, ortaç f (2020). Binary grading may be more appropriate for endometrial cancer. Journal of the Turkish-German Gynecological Association, 21(3), 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
Chicago	Koyuncu Kazibe,Altın Duygu,Turgay Batuhan,Varli Bulut,Konuralp Atakul Bahar,Şükür Yavuz Emre,Taşkın Salih,ortaç fırat Binary grading may be more appropriate for endometrial cancer. Journal of the Turkish-German Gynecological Association 21, no.3 (2020): 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
MLA	Koyuncu Kazibe,Altın Duygu,Turgay Batuhan,Varli Bulut,Konuralp Atakul Bahar,Şükür Yavuz Emre,Taşkın Salih,ortaç fırat Binary grading may be more appropriate for endometrial cancer. Journal of the Turkish-German Gynecological Association, vol.21, no.3, 2020, ss.163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
AMA	Koyuncu K,Altın D,Turgay B,Varli B,Konuralp Atakul B,Şükür Y,Taşkın S,ortaç f Binary grading may be more appropriate for endometrial cancer. Journal of the Turkish-German Gynecological Association. 2020; 21(3): 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
Vancouver	Koyuncu K,Altın D,Turgay B,Varli B,Konuralp Atakul B,Şükür Y,Taşkın S,ortaç f Binary grading may be more appropriate for endometrial cancer. Journal of the Turkish-German Gynecological Association. 2020; 21(3): 163 - 170. 10.4274/jtgga.galenos.2019.2019.0068
IEEE	Koyuncu K,Altın D,Turgay B,Varli B,Konuralp Atakul B,Şükür Y,Taşkın S,ortaç f "Binary grading may be more appropriate for endometrial cancer." Journal of the Turkish-German Gynecological Association, 21, ss.163 - 170, 2020. 10.4274/jtgga.galenos.2019.2019.0068
ISNAD	Koyuncu, Kazibe vd. "Binary grading may be more appropriate for endometrial cancer". Journal of the Turkish-German Gynecological Association 21/3 (2020), 163-170. https://doi.org/10.4274/jtgga.galenos.2019.2019.0068