Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume

Bozkuş, Yusuf; ALTIN, Cihan; Yılmaz, Mustafa; MUDERRİSOGLU, IBRAHIM HALDUN; Erol, Varlık

doi:10.5222/MMJ.2018.16442

Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume

Cihan ALTIN, (Başkent Üniversitesi,Kardiyoloji Anabilim Dalı, İzmir, Türkiye)

Varlık EROL, (Başkent Üniversitesi,Genel Cerrahi Anabilim Dalı, İzmir, Türkiye)

Mustafa YILMAZ, (Başkent Üniversitesi,Kardiyoloji Anabilim Dalı, Adana, Türkiye)

Yusuf BOZKUŞ, (Başkent Üniversitesi,Endokrinoloji Anabilim Dalı, Ankara, Türkiye)

Haldun MÜDERRİSOĞLU (Başkent Üniversitesi,Kardiyoloji Anabilim Dalı, Ankara, Türkiye)

Medeniyet Medical Journal

0 2

Yıl: 2018 Cilt: 33 Sayı: 4 Sayfa Aralığı: 278 - 284 Metin Dili: İngilizce DOI: 10.5222/MMJ.2018.16442 İndeks Tarihi: 30-11-2020

Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume

Öz:

Aim: Elevated red blood cell distribution width (RDW) and mean platelet volume (MPV) levels which are closely associated with chronic inflammation and platelet aggregation are suggested as independent predictors of obesity and cardiovascular diseases. However influence of significant weight loss following bariatric surgery on these parameters is unknown. Therefore we aimed to find out the effect of significant weight loss following laparosco-pic sleeve gastrectomy (LSG) on RDW and MPV levels.Methods: The medical data of 98 morbid obese subjects (25 male, 73 female) who were operated between February 2015 and June 2017 according to indications of bariatric surgery in current guide-lines including body mass index (BMI) >40 kg/m2 or BMI= 35-40 kg/m2 with additional comorbidities were recorded. The difference bet-ween baseline and values at one year was expressed as a delta (Δ).Results: The mean age of our study population was 41.89±11.99 years and mean weight loss in one year after LSG was 45.41±13.13 kg (36.5%). BMI decreased from 46.60±7.11 kg/m2 to 29.58±4.63 kg/m2. Compared to the baseline, significant decreases in RDW (14.61±1.69 % vs. 13.71±2.10 %; p<0.01) and MPV (8.63±1.45 vs. 7.92±1.24 fL, p<0.001) levels were found in the postoperative one-year values. In addition; ΔVKI was positively correlated with ΔRDW (r=0.343, p<0.01) and ΔMPV (r=0.322, p<0.01).Conclusion: We found that morbid obese subjects have signifi-cantly decreased RDW and MPV levels which are correlated to their weight loss in one-year follow-up after LSG. If we think that several factors may affect these parameters, conduction offurther pros-pective large-scale studies are needed.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ALTIN C, Erol V, Yılmaz M, Bozkuş Y, MUDERRİSOGLU I (2018). Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. , 278 - 284. 10.5222/MMJ.2018.16442
Chicago	ALTIN Cihan,Erol Varlık,Yılmaz Mustafa,Bozkuş Yusuf,MUDERRİSOGLU IBRAHIM HALDUN Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. (2018): 278 - 284. 10.5222/MMJ.2018.16442
MLA	ALTIN Cihan,Erol Varlık,Yılmaz Mustafa,Bozkuş Yusuf,MUDERRİSOGLU IBRAHIM HALDUN Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. , 2018, ss.278 - 284. 10.5222/MMJ.2018.16442
AMA	ALTIN C,Erol V,Yılmaz M,Bozkuş Y,MUDERRİSOGLU I Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. . 2018; 278 - 284. 10.5222/MMJ.2018.16442
Vancouver	ALTIN C,Erol V,Yılmaz M,Bozkuş Y,MUDERRİSOGLU I Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. . 2018; 278 - 284. 10.5222/MMJ.2018.16442
IEEE	ALTIN C,Erol V,Yılmaz M,Bozkuş Y,MUDERRİSOGLU I "Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume." , ss.278 - 284, 2018. 10.5222/MMJ.2018.16442
ISNAD	ALTIN, Cihan vd. "Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume". (2018), 278-284. https://doi.org/10.5222/MMJ.2018.16442

APA	ALTIN C, Erol V, Yılmaz M, Bozkuş Y, MUDERRİSOGLU I (2018). Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. Medeniyet Medical Journal, 33(4), 278 - 284. 10.5222/MMJ.2018.16442
Chicago	ALTIN Cihan,Erol Varlık,Yılmaz Mustafa,Bozkuş Yusuf,MUDERRİSOGLU IBRAHIM HALDUN Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. Medeniyet Medical Journal 33, no.4 (2018): 278 - 284. 10.5222/MMJ.2018.16442
MLA	ALTIN Cihan,Erol Varlık,Yılmaz Mustafa,Bozkuş Yusuf,MUDERRİSOGLU IBRAHIM HALDUN Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. Medeniyet Medical Journal, vol.33, no.4, 2018, ss.278 - 284. 10.5222/MMJ.2018.16442
AMA	ALTIN C,Erol V,Yılmaz M,Bozkuş Y,MUDERRİSOGLU I Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. Medeniyet Medical Journal. 2018; 33(4): 278 - 284. 10.5222/MMJ.2018.16442
Vancouver	ALTIN C,Erol V,Yılmaz M,Bozkuş Y,MUDERRİSOGLU I Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume. Medeniyet Medical Journal. 2018; 33(4): 278 - 284. 10.5222/MMJ.2018.16442
IEEE	ALTIN C,Erol V,Yılmaz M,Bozkuş Y,MUDERRİSOGLU I "Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume." Medeniyet Medical Journal, 33, ss.278 - 284, 2018. 10.5222/MMJ.2018.16442
ISNAD	ALTIN, Cihan vd. "Effects of significant weight loss following bariatric surgery on red cell distribution width and mean platelet volume". Medeniyet Medical Journal 33/4 (2018), 278-284. https://doi.org/10.5222/MMJ.2018.16442