The relationship between the heart-type fatty acid binding protein levels,carotid intima media thickness and epicardial fat thickness in patients withobstructive sleep apnea syndromeIntroduction: In this study, we aimed to evaluate the relationship between carotid artery intima-media thickness, epicardial fat thickness measurement and thelevels of heart-type fatty acid binding protein (hFABP) in patients with obstructive sleep apnea syndrome (OSAS).Materials and Methods: Ninety-nine newly diagnosed OSAS patients and fiftynon-OSAS control subjects were enrolled in this study. In both groups, demographic data such as age, sex, body mass index (BMI) were recorded andcarotid intima-media thickness (CMIT) and epicardial fat thickness (EFT) weremeasured. hFABP levels were determined using the enzyme-linked immunosorbent assay (ELISA) method according to the manufacturer’s protocols.Results: Patients with OSAS 67% male, 33% female gender is determined.The mean age of control group was 43.28 ± 12.12 years and group of OSASwas 47.85 ± 11.55 years (p= 0.026). In OSAS group; 38 mild OSAS(38.38%), 23 moderate OSAS (23.23%) and 38 severe OSAS (38.38%)patients were identified. In OSAS patients, average of apnea hypopnea index (AHI) was 29.83/hours. A positive correlation was observed between BMI with EFT and CMIT (p< 0.05). hFABP levels in OSAS groupaverage was 2.65 ± 2.1 ng/mL and in control group average was 1.62 ± 0.90 ng/mL and this was statistically significant (p= 0.002).EFT, in the control group average was 5.3 ± 2.04 mm, while the average was 4.3 ± 1.79 mm in the OSAS group (p= 0.019). Thecorrelation was observed between the CMIT and EFT (p< 0.001). There was no significant difference in BMI and gender betweenOSAS and control groups. No accompanying cardiovascular disease was detected in patients with OSAS.Conclusion: This study suggests EFT and hFABP can be used as a predictive value in determining cardiovascular risk in OSAS patients.