Objective: Transcatheter aortic valve implantation (TAVI) is agood alternative to surgical aortic valve replacement (SAVR)in severe aortic stenosis patients who are at intermediateor high risk, or other cases that are considered unsuitablefor SAVR. TAVI is most often performed on elderly patients,and although conventional risk scores include a number ofcomorbidities, they do not take into account functional decline specific to elderly patients. The prognostic nutritionalindex (PNI), which is a simple and effective parameter forboth nutritional and inflammatory status, reflects functionaldecline in the elderly. The aim of this study was to determinethe effect of the PNI on short-term survival after TAVI.Methods: The PNI values of 302 patients who underwentTAVI were analyzed. The study population was dividedinto 2 groups according to a PNI cut-off value: PNI >43.37(n=213; 70%) and PNI <43.37 (n=89; 30%).Results: Patients with a lower PNI score had a significantlyhigher mortality rate in the initial 30-day period following theprocedure than patients with a higher PNI score (3.3% vs.31.5%; p<0.001). Major vascular complications and cardiac tamponade were significantly more frequent in the lowerPNI group. The cut-off value of the PNI for 30-day survivalwas 43.37, with 94.3% specificity and 73.4% sensitivity andthe negative predictive value of the PNI was 96.7%. ThePNI score was found to be an independent risk factor for30-day mortality after TAVI.Conclusion: A higher PNI score was associated with shortterm survival and fewer post-TAVI complications.