Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients
Yıl: 2020 Cilt: 48 Sayı: 6 Sayfa Aralığı: 594 - 604 Metin Dili: İngilizce DOI: 10.5543/tkda.2020.72246 İndeks Tarihi: 05-12-2020
Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients
Öz: Objective: Although obesity is a risk factor for heart failure, studies analyzing the effect of obesity on heart functions have primarily examined the left side of the heart. Thisstudy is an analysis of the effect of the severity of obesity onright heart functions and a comparison of the sensitivity andspecificity of different echocardiographic modalities in thedetection of right heart dysfunction.Methods: A total of 116 subjects were included and divided into 4 age- and sex-matched groups according to bodymass index (BMI) values. Right heart functions were evaluated with transthoracic echocardiography.Results: The right atrium (RA) diameter was significantlylarger in the obese group (OBG) and the morbidly obesegroup (MOG); the right ventricle (RV) diameter was significantly larger only in the MOG. In the overweight group,the OBG, and the MOG, the RV isovolumic acceleration(R-IVA) was significantly lower (p=0.020; p<0.001; p<0.001,respectively) and the myocardial performance index (MPI)value was significantly higher (p=0.015; p<0.001; p<0.001,respectively). There was a strong positive correlation between the MPI and the BMI (r=0.833, p<0.001), and a moderate negative correlation between the R-IVA and the BMI(r=-0.547, p<0.001). A cut-off value of 30.45 kg/m2 was associated with 93.3% sensitivity and 94.3% specificity in theprediction of RV systolic dysfunction defined by the MPI. Acut-off value of 30.50 kg/m2 was associated with 76.7% sensitivity and 72.3% specificity in the prediction of RV systolicdysfunction defined by the R-IVA.Conclusion: Obesity significantly affected right heart function and there was a significant correlation between the degree of obesity and right heart functional deterioration. TheBMI could be used to predict RV systolic dysfunction.
Anahtar Kelime: Obez hastalarda sağ ventriküler disfonksiyonunun saptanmasında miyokardiyal performans indeksi ile isovolumetrik kasılma fazındaki sağ ventriküler akselerasyonun karşılaştırılması
Öz: Amaç: Obezitenin kalp yetersizliği için bir risk faktörü olduğu bilinmesine rağmen, bu konuda yapılmış çalışmaların çoğunda obezitenin sol kalp fonksiyonları üzerine etkisi incelenmiştir. Bu çalışmada, obezite derecesinin sağ kalp fonksiyonları üzerine etkisini incelemeyi, farklı ekokardiyografik modalitelerin sağ ventriküler disfonksiyonu belirlemedeki duyarlılık ve özgüllüğünü karşılaştırmayı amaçladık. Yöntemler: Toplam 116 hasta çalışmaya dahil edildi. Dahil edilen hastalar beden kitle indeksine (BKİ) göre, yaş ve cinsiyet açısından eşleştirilmiş 4 gruba ayrıldı. Transtorasik ekokardiyografi ile sağ kalp fonksiyonları değerlendirildi. Bulgular: Sağ atriyum (RA) çapı; obez ve morbid obez grupta, sağ ventriül (RV) çapı ise sadece morbid obez grupta anlamlı derecede daha büyüktü. Sağ ventriküler isovolumetrik akselerasyon (R-IVA); fazla kilolu gruptan itibaren anlamlı derecede daha düşüktü (sırasıyla, p=0.020; p<0.001; p<0.001). Miyokart performans indeksi (MPİ) ise fazla kilolu gruptan itibaren anlamlı derecede daha yüksekti (sırasıyla, p=0.015; p<0.001; p<0.001) MPİ ile BKİ arasında güçlü pozitif korelasyon r=0.833, p<0.001), R-IVA ile BKİ arasında ise orta derecede negatif korelasyon = (-0.547, p<0.001) mevcuttu. Reciever operator curve analizi BKİ 30.50 kg/m2kestirim değerinin R-IVA için %76.7 duyarlılık ve %72.3 özgüllük ile, BKİ 30.45 kg/m2kestirim değerinin ise MPİ için %93.3 özgüllük ve %94.3 duyarlılıkla RV sistolik disfonksiyonunu öngördürdüğünü göstermiştir. Sonuç: Bu çalışmada, bilinen hastalığı olmayan sağlıklı bireylerde obezitenin sağ kalp fonksiyonlarını anlamlı derecede etkilediği ve obezite derecesi ile sağ kalp fonksiyonlarındaki bozulma arasında anlamlı korelasyon olduğu gösterilmiştir. Ayrıca BKİ’nin RV sistolik disfonksiyonunu öngörmede tek başına kullanılabileceği gösterilmiştir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Ziyrek M, alpaydın m (2020). Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. , 594 - 604. 10.5543/tkda.2020.72246 |
| Chicago | Ziyrek Murat,alpaydın mehmet sertaç Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. (2020): 594 - 604. 10.5543/tkda.2020.72246 |
| MLA | Ziyrek Murat,alpaydın mehmet sertaç Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. , 2020, ss.594 - 604. 10.5543/tkda.2020.72246 |
| AMA | Ziyrek M,alpaydın m Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. . 2020; 594 - 604. 10.5543/tkda.2020.72246 |
| Vancouver | Ziyrek M,alpaydın m Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. . 2020; 594 - 604. 10.5543/tkda.2020.72246 |
| IEEE | Ziyrek M,alpaydın m "Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients." , ss.594 - 604, 2020. 10.5543/tkda.2020.72246 |
| ISNAD | Ziyrek, Murat - alpaydın, mehmet sertaç. "Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients". (2020), 594-604. https://doi.org/10.5543/tkda.2020.72246 |
| APA | Ziyrek M, alpaydın m (2020). Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. Türk Kardiyoloji Derneği Arşivi, 48(6), 594 - 604. 10.5543/tkda.2020.72246 |
| Chicago | Ziyrek Murat,alpaydın mehmet sertaç Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. Türk Kardiyoloji Derneği Arşivi 48, no.6 (2020): 594 - 604. 10.5543/tkda.2020.72246 |
| MLA | Ziyrek Murat,alpaydın mehmet sertaç Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. Türk Kardiyoloji Derneği Arşivi, vol.48, no.6, 2020, ss.594 - 604. 10.5543/tkda.2020.72246 |
| AMA | Ziyrek M,alpaydın m Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. Türk Kardiyoloji Derneği Arşivi. 2020; 48(6): 594 - 604. 10.5543/tkda.2020.72246 |
| Vancouver | Ziyrek M,alpaydın m Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients. Türk Kardiyoloji Derneği Arşivi. 2020; 48(6): 594 - 604. 10.5543/tkda.2020.72246 |
| IEEE | Ziyrek M,alpaydın m "Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients." Türk Kardiyoloji Derneği Arşivi, 48, ss.594 - 604, 2020. 10.5543/tkda.2020.72246 |
| ISNAD | Ziyrek, Murat - alpaydın, mehmet sertaç. "Comparison of myocardial performance index and right ventricular myocardial acceleration during isovolumic contraction in detection of right ventricular dysfunction in obese patients". Türk Kardiyoloji Derneği Arşivi 48/6 (2020), 594-604. https://doi.org/10.5543/tkda.2020.72246 |
