Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center

Yıl: 2019 Cilt: 3 Sayı: 4 Sayfa Aralığı: 327 - 332 Metin Dili: İngilizce DOI: 10.14744/ejmi.2019.19323 İndeks Tarihi: 07-12-2020

Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center

Öz:
Objectives: This study aimed to determine how ventilator - associated pneumonia (VAP) frequency, and antibioticsusceptibilities are affected by the changes in the intensive care unit (ICU) conditions in adult patients.Methods: In this retrospective study, 457 VAP patients diagnosed in the ICUs of a training hospital between 2008 and2017 were analyzed. Alterations in VAP rates during this period were evaluated.Results: Our results indicated that the improvement of physical conditions, and VAP prevention measures yielded aremarkable decline in the rates of VAP. VAP rates (cases per 1000 ventilator-days) decreased significantly between before2013 and 2013-2017 periods (from 16.1 to 7.1; p<0.0000001). A total of 504 VAP episodes developed and 569microorganisms were identified. The most frequent microorganisms were Acinetobacter baumanii (33.7%), Pseudomonasaeruginosa (31.6%), Klebsiella pneumonia (12%). The resistances against sulbactam-ampicillin, imipenem, andmeropenem were increased significantly after 2013. (p=0.002, p<0.001, p=0.001; respectively.) There was a noteworthysurge in resistances against colistin (p=0.010) in Gram - negative bacteria and teicoplanin in Gram - positive bacteria(p=0.044).Conclusion: The study shows that the rates of VAP can be decreased with collaboration with other disciplines, adherenceto preventative measures and continue education of healthcare workers.
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Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Bibliyografik
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APA Çalık Ş, ARI A, tekgül z, Özkarakaş H, GENÇ N, Cifci H, Tosun S, Yiş R (2019). Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. , 327 - 332. 10.14744/ejmi.2019.19323
Chicago Çalık Şebnem,ARI ALPAY,tekgül zeki tuncel,Özkarakaş Hüseyin,GENÇ Neslihan,Cifci Hazal ezgi,Tosun Selma,Yiş Reyhan Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. (2019): 327 - 332. 10.14744/ejmi.2019.19323
MLA Çalık Şebnem,ARI ALPAY,tekgül zeki tuncel,Özkarakaş Hüseyin,GENÇ Neslihan,Cifci Hazal ezgi,Tosun Selma,Yiş Reyhan Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. , 2019, ss.327 - 332. 10.14744/ejmi.2019.19323
AMA Çalık Ş,ARI A,tekgül z,Özkarakaş H,GENÇ N,Cifci H,Tosun S,Yiş R Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. . 2019; 327 - 332. 10.14744/ejmi.2019.19323
Vancouver Çalık Ş,ARI A,tekgül z,Özkarakaş H,GENÇ N,Cifci H,Tosun S,Yiş R Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. . 2019; 327 - 332. 10.14744/ejmi.2019.19323
IEEE Çalık Ş,ARI A,tekgül z,Özkarakaş H,GENÇ N,Cifci H,Tosun S,Yiş R "Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center." , ss.327 - 332, 2019. 10.14744/ejmi.2019.19323
ISNAD Çalık, Şebnem vd. "Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center". (2019), 327-332. https://doi.org/10.14744/ejmi.2019.19323
APA Çalık Ş, ARI A, tekgül z, Özkarakaş H, GENÇ N, Cifci H, Tosun S, Yiş R (2019). Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. Eurasian Journal of Medical Investigation, 3(4), 327 - 332. 10.14744/ejmi.2019.19323
Chicago Çalık Şebnem,ARI ALPAY,tekgül zeki tuncel,Özkarakaş Hüseyin,GENÇ Neslihan,Cifci Hazal ezgi,Tosun Selma,Yiş Reyhan Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. Eurasian Journal of Medical Investigation 3, no.4 (2019): 327 - 332. 10.14744/ejmi.2019.19323
MLA Çalık Şebnem,ARI ALPAY,tekgül zeki tuncel,Özkarakaş Hüseyin,GENÇ Neslihan,Cifci Hazal ezgi,Tosun Selma,Yiş Reyhan Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. Eurasian Journal of Medical Investigation, vol.3, no.4, 2019, ss.327 - 332. 10.14744/ejmi.2019.19323
AMA Çalık Ş,ARI A,tekgül z,Özkarakaş H,GENÇ N,Cifci H,Tosun S,Yiş R Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. Eurasian Journal of Medical Investigation. 2019; 3(4): 327 - 332. 10.14744/ejmi.2019.19323
Vancouver Çalık Ş,ARI A,tekgül z,Özkarakaş H,GENÇ N,Cifci H,Tosun S,Yiş R Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center. Eurasian Journal of Medical Investigation. 2019; 3(4): 327 - 332. 10.14744/ejmi.2019.19323
IEEE Çalık Ş,ARI A,tekgül z,Özkarakaş H,GENÇ N,Cifci H,Tosun S,Yiş R "Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center." Eurasian Journal of Medical Investigation, 3, ss.327 - 332, 2019. 10.14744/ejmi.2019.19323
ISNAD Çalık, Şebnem vd. "Ventilator-Associated Pneumonia: Microbiology, Antibiotic Resistance, Changing Trends, and Clinical Implications from the 10-Year Experience of a Single Center". Eurasian Journal of Medical Investigation 3/4 (2019), 327-332. https://doi.org/10.14744/ejmi.2019.19323