Role of whole blood markers in carbon monoxide poisoning
Yıl: 2019 Cilt: 44 Sayı: Ek Sayı 1 Sayfa Aralığı: 197 - 201 Metin Dili: İngilizce DOI: 10.17826/cumj.553701 İndeks Tarihi: 08-12-2020
Role of whole blood markers in carbon monoxide poisoning
Öz: Purpose: Carbon monoxide (CO) poisoning is one of themost common causes of fatal suicide or accidentalpoisoning worldwide. There is no specific biomarker in thediagnosis. Therefore, the role of whole blood parametersin CO poisoning was investigated.Material and Methods: A total of 442 patients diagnosedwith CO intoxication at the emergency departmentbetween January 1, 2014 and January 1, 2016 were includedin the study retrospectively. The demographiccharacteristics of the patient group and the complete bloodresults were obtained from the hospital registry system.The control group consisted of 100 patients presentingwith similar complaints to the emergency department.Leukocyte (WBC), red cell distribution width (RDW),platelet, lymphocyte, neutrophil, neutrophil lymphocyteratio (NLR) and platelet lymphocyte ratio (PLR) values ofboth groups were compared statistically.Results: The patient and control groups were similar inage and gender. The WBC, RDW, Platelet, Lymphocyte,Neutrophil, NLR and PLR levels of the patient group weresignificantly higher compared to the control group.However, there was no significant correlation betweenpatient admission time and Glaskow Coma Scale (GCS),carboxyhemoglobin (COHb), RDW, NLR and PLR levels.Conclusion: Our study suggested that RDW, NLR andPLR levels have potential to be a useful marker for thediagnosis of CO poisoning.
Anahtar Kelime: Karbonmonoksit zehirlenmesi tanısında tam kan belirteçlerinin rolü
Öz: Amaç: Karbonmonoksit (CO) zehirlenmesi dünya çapındaki ölümcül intihar veya kazara zehirlenmelerin en yaygın nedenlerinden birisidir. Tanısında spesifik bir biyobelirteç yoktur. Bu sebeple çalışmada CO zehirlenmesinde tam kan parametreleri’nin rolü araştırılmıştır. Gereç ve Yöntem: Çalışmada 1 Ocak 2014 – 1 Ocak 2016 tarihleri arasında acil serviste CO zehirlenmesi tanısı alan ve dışlama kriterlerini sağlayan toplam 442 hasta retrospektif olarak incelendi. Hasta grubunun demografik özellikleri ve tam kan sonuçlarına hastane kayıt sisteminden ulaşıldı. Kontrol grubu acil servise benzer şikâyetler ile başvuran 100 hastadan oluşturuldu. Her iki grubun lökosit (WBC), kırmızı hücre dağılım genişliği (RDW), platelet, lenfosit, nötrofil, nötrofil-lenfosit oranı (NLR) ve platelet-lenfosit oranı (PLR) değerleri istatistiksel olarak karşılaştırıldı. Bulgular: Hasta ve kontrol grubu yaş ve cinsiyet bakımından birbirleri ile benzerdi. Hasta grubunun WBC, RDW, Platelet, Lenfosit, Nötrofil, NLR ve PLR değerleri kontrol grubu ile kıyaslandığında anlamlı derece yüksek bulundu. Ancak hasta yatış süreleri ile Glaskow Koma Skalası (GKS), karboksihemoglobin (COHb), RDW, NLR ve PLR düzeyleri arasında anlamlı bir korelasyon bulunmamıştır. Sonuç: Çalışmamız RDW, NLR ve PLR düzeylerinin CO zehirlenmesi tanısını öngörmede kullanılabilir bir biyobelirteç olma potansiyeli olduğunu düşündürmüştür.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA | ERTEKİN B, Kocak S, Acar T, ERDEMİR ÖZTÜRK E, DEMİR L (2019). Role of whole blood markers in carbon monoxide poisoning. , 197 - 201. 10.17826/cumj.553701 |
Chicago | ERTEKİN Birsen,Kocak Sedat,Acar Tarık,ERDEMİR ÖZTÜRK Esma,DEMİR Lütfi Saltuk Role of whole blood markers in carbon monoxide poisoning. (2019): 197 - 201. 10.17826/cumj.553701 |
MLA | ERTEKİN Birsen,Kocak Sedat,Acar Tarık,ERDEMİR ÖZTÜRK Esma,DEMİR Lütfi Saltuk Role of whole blood markers in carbon monoxide poisoning. , 2019, ss.197 - 201. 10.17826/cumj.553701 |
AMA | ERTEKİN B,Kocak S,Acar T,ERDEMİR ÖZTÜRK E,DEMİR L Role of whole blood markers in carbon monoxide poisoning. . 2019; 197 - 201. 10.17826/cumj.553701 |
Vancouver | ERTEKİN B,Kocak S,Acar T,ERDEMİR ÖZTÜRK E,DEMİR L Role of whole blood markers in carbon monoxide poisoning. . 2019; 197 - 201. 10.17826/cumj.553701 |
IEEE | ERTEKİN B,Kocak S,Acar T,ERDEMİR ÖZTÜRK E,DEMİR L "Role of whole blood markers in carbon monoxide poisoning." , ss.197 - 201, 2019. 10.17826/cumj.553701 |
ISNAD | ERTEKİN, Birsen vd. "Role of whole blood markers in carbon monoxide poisoning". (2019), 197-201. https://doi.org/10.17826/cumj.553701 |
APA | ERTEKİN B, Kocak S, Acar T, ERDEMİR ÖZTÜRK E, DEMİR L (2019). Role of whole blood markers in carbon monoxide poisoning. Cukurova Medical Journal, 44(Ek Sayı 1), 197 - 201. 10.17826/cumj.553701 |
Chicago | ERTEKİN Birsen,Kocak Sedat,Acar Tarık,ERDEMİR ÖZTÜRK Esma,DEMİR Lütfi Saltuk Role of whole blood markers in carbon monoxide poisoning. Cukurova Medical Journal 44, no.Ek Sayı 1 (2019): 197 - 201. 10.17826/cumj.553701 |
MLA | ERTEKİN Birsen,Kocak Sedat,Acar Tarık,ERDEMİR ÖZTÜRK Esma,DEMİR Lütfi Saltuk Role of whole blood markers in carbon monoxide poisoning. Cukurova Medical Journal, vol.44, no.Ek Sayı 1, 2019, ss.197 - 201. 10.17826/cumj.553701 |
AMA | ERTEKİN B,Kocak S,Acar T,ERDEMİR ÖZTÜRK E,DEMİR L Role of whole blood markers in carbon monoxide poisoning. Cukurova Medical Journal. 2019; 44(Ek Sayı 1): 197 - 201. 10.17826/cumj.553701 |
Vancouver | ERTEKİN B,Kocak S,Acar T,ERDEMİR ÖZTÜRK E,DEMİR L Role of whole blood markers in carbon monoxide poisoning. Cukurova Medical Journal. 2019; 44(Ek Sayı 1): 197 - 201. 10.17826/cumj.553701 |
IEEE | ERTEKİN B,Kocak S,Acar T,ERDEMİR ÖZTÜRK E,DEMİR L "Role of whole blood markers in carbon monoxide poisoning." Cukurova Medical Journal, 44, ss.197 - 201, 2019. 10.17826/cumj.553701 |
ISNAD | ERTEKİN, Birsen vd. "Role of whole blood markers in carbon monoxide poisoning". Cukurova Medical Journal 44/Ek Sayı 1 (2019), 197-201. https://doi.org/10.17826/cumj.553701 |