Yıl: 2020 Cilt: 23 Sayı: 1 Sayfa Aralığı: 148 - 156 Metin Dili: İngilizce DOI: 10.18016/ksutarimdoga.vi.589279 İndeks Tarihi: 24-02-2021

In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey

Öz:
Centaurea L. species were used as medicinal plants among thepeople for treatment of the common cold, abscesses, peptic ulcers,hemorrhoid and diabetes etc.. In the present study, antiradicalproperties, phytochemical contents, antimicrobial andantiproliferative activities of three Centaurea species wereinvestigated. Centaurea saligna (K.Koch) Wagenitz methanol(99.94%), Centaurea virgata Lam. methanol (98.23%) and water(98.10%) extracts were showed higher ABTS scavenging than trolox(96.79%). Centaurea kurdica Reichardt extracts showed loweractivity than trolox for all the antiradical assays. Centaurea extractsexhibited antimicrobial activity against to some microorganisms. Itwas determined that these Centaurea species contain high amount oftotal flavonoid, phenolic and proanthocyanidin, phenolic acids,phytosterols and unsaturated fatty acids. Also, three Centaureaextracts showed very high antiproliferative property on LNCaP,HCT-116, MCF-7 cancer cell lines.
Anahtar Kelime:

Doğu Anadolu, Türkiye’de Yetişen Üç Centaurea L. Türünün in vitro Biyolojik Değerlendirilmesi ve Fitokimyasal Özellikleri

Öz:
Centaurea türleri halk arasında tıbbi bitkiler olarak soğuk algınlığı, apse, peptik ülser, hemoroit, diyabet vb. hastalıkların tedavisinde kullanılmaktadırlar. Sunulan çalışmada, üç Centaurea türünün antiradikal özellikleri, fitokimyasal içerikleri, antimikrobiyal ve antiproliferatif aktiviteleri incelenmiştir. Centaurea saligna (K.Koch) Wagenitz metanol (99.94%), Centaurea virgata Lam. metanol (98.23%) ve su (98.10%) ekstraktları standart antioksidan trolokstan (96.79%) daha yüksek ABTS yok etme aktivitesi göstermiştir. Centaurea kurdica Reichardt ekstraktları trolokstan daha düşük antiradikal aktivite göstermiştir. Centaurea ekstraktları bazı mikroorganizmalara karşı antimikrobiyal aktivite göstermiştir. Centaurea türlerinin yüksek miktarda toplam flavonoit, fenolik ve proantosiyanidin, fenolik asitler, fitosteroller ve doymamış yağ asitleri içerdiği belirlenmiştir. Ayrıca bu üç Centaurea ekstraktları MCF-7, HCT-116 ve LNCaP kanser hücre serileri üzerinde çok yüksek antiproliferatif özellik göstermiştir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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APA KESER S, KESER F, Turkoglu İ, KAYGILI O, Tekin S, DEMİR E, KARATEPE M, Yılmaz, Yilmaz Ö, KIRBAG S, Sandal S, TURKOGLU S (2020). In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. , 148 - 156. 10.18016/ksutarimdoga.vi.589279
Chicago KESER Serhat,KESER Fatma,Turkoglu İsmail,KAYGILI OMER,Tekin Suat,DEMİR ERSİN,KARATEPE MUSTAFA,Yılmaz, Yilmaz Ökkeş, Okkes,KIRBAG Sevda,Sandal Suleyman,TURKOGLU Semra In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. (2020): 148 - 156. 10.18016/ksutarimdoga.vi.589279
MLA KESER Serhat,KESER Fatma,Turkoglu İsmail,KAYGILI OMER,Tekin Suat,DEMİR ERSİN,KARATEPE MUSTAFA,Yılmaz, Yilmaz Ökkeş, Okkes,KIRBAG Sevda,Sandal Suleyman,TURKOGLU Semra In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. , 2020, ss.148 - 156. 10.18016/ksutarimdoga.vi.589279
AMA KESER S,KESER F,Turkoglu İ,KAYGILI O,Tekin S,DEMİR E,KARATEPE M,Yılmaz, Yilmaz Ö,KIRBAG S,Sandal S,TURKOGLU S In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. . 2020; 148 - 156. 10.18016/ksutarimdoga.vi.589279
Vancouver KESER S,KESER F,Turkoglu İ,KAYGILI O,Tekin S,DEMİR E,KARATEPE M,Yılmaz, Yilmaz Ö,KIRBAG S,Sandal S,TURKOGLU S In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. . 2020; 148 - 156. 10.18016/ksutarimdoga.vi.589279
IEEE KESER S,KESER F,Turkoglu İ,KAYGILI O,Tekin S,DEMİR E,KARATEPE M,Yılmaz, Yilmaz Ö,KIRBAG S,Sandal S,TURKOGLU S "In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey." , ss.148 - 156, 2020. 10.18016/ksutarimdoga.vi.589279
ISNAD KESER, Serhat vd. "In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey". (2020), 148-156. https://doi.org/10.18016/ksutarimdoga.vi.589279
APA KESER S, KESER F, Turkoglu İ, KAYGILI O, Tekin S, DEMİR E, KARATEPE M, Yılmaz, Yilmaz Ö, KIRBAG S, Sandal S, TURKOGLU S (2020). In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 23(1), 148 - 156. 10.18016/ksutarimdoga.vi.589279
Chicago KESER Serhat,KESER Fatma,Turkoglu İsmail,KAYGILI OMER,Tekin Suat,DEMİR ERSİN,KARATEPE MUSTAFA,Yılmaz, Yilmaz Ökkeş, Okkes,KIRBAG Sevda,Sandal Suleyman,TURKOGLU Semra In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 23, no.1 (2020): 148 - 156. 10.18016/ksutarimdoga.vi.589279
MLA KESER Serhat,KESER Fatma,Turkoglu İsmail,KAYGILI OMER,Tekin Suat,DEMİR ERSİN,KARATEPE MUSTAFA,Yılmaz, Yilmaz Ökkeş, Okkes,KIRBAG Sevda,Sandal Suleyman,TURKOGLU Semra In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, vol.23, no.1, 2020, ss.148 - 156. 10.18016/ksutarimdoga.vi.589279
AMA KESER S,KESER F,Turkoglu İ,KAYGILI O,Tekin S,DEMİR E,KARATEPE M,Yılmaz, Yilmaz Ö,KIRBAG S,Sandal S,TURKOGLU S In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi. 2020; 23(1): 148 - 156. 10.18016/ksutarimdoga.vi.589279
Vancouver KESER S,KESER F,Turkoglu İ,KAYGILI O,Tekin S,DEMİR E,KARATEPE M,Yılmaz, Yilmaz Ö,KIRBAG S,Sandal S,TURKOGLU S In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey. Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi. 2020; 23(1): 148 - 156. 10.18016/ksutarimdoga.vi.589279
IEEE KESER S,KESER F,Turkoglu İ,KAYGILI O,Tekin S,DEMİR E,KARATEPE M,Yılmaz, Yilmaz Ö,KIRBAG S,Sandal S,TURKOGLU S "In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey." Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi, 23, ss.148 - 156, 2020. 10.18016/ksutarimdoga.vi.589279
ISNAD KESER, Serhat vd. "In Vitro Biological Evaluation and Phytochemical Contents of Three Centaurea L. Species Growing from Eastern Anatolia in Turkey". Kahramanmaraş Sütçü İmam Üniversitesi Tarım ve Doğa Dergisi 23/1 (2020), 148-156. https://doi.org/10.18016/ksutarimdoga.vi.589279