Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy

GORDUK, Semih

doi:10.18596/jotcsa.812081

Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy

Semih Gorduk (Yıldız Teknik Üniversitesi, Fen Edebiyat Fakültesi, Kimya Bölümü, 34210 İstanbul, Türkiye)

Journal of the Turkish Chemical Society, Section A: Chemistry

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Yıl: 2021 Cilt: 8 Sayı: 1 Sayfa Aralığı: 279 - 288 Metin Dili: İngilizce DOI: 10.18596/jotcsa.812081 İndeks Tarihi: 28-02-2021

Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy

Öz:

Phthalocyanines (Pcs) are macrocyclic compounds of great importance. Different metals andligands can be used in the synthesis of Pc compounds and they give different properties to Pcs. Thus, theapplications of Pcs have been increasing every day. One of the most important areas of use of Pcs isphotodynamic therapy (PDT) application. The scope of this study is synthesis, characterization, andinvestigation of singlet oxygen generation property of new peripherally tetrakis(benzodioxane) substitutedindium(III) chloride phthalocyanine (InCIPc). The compound may be used as a potential photosensitizer forPDT applications. The new compound was characterized by various techniques such as elemental analysis,FT-IR, 1H NMR, MS, and UV–Vis techniques. Furthermore, photophysical and photochemical properties of thesynthesized Pc were investigated for PDT studies. At the same time, the effect of combination of heavyindium atom and benzodioxane groups bearing oxygen atom on solubility and photophysicochemicalproperties was discussed. The results showed that this compound exhibits good solubility in DMSO andshows high singlet oxygen production (ΦΔ: 0.76). According to the displayed properties and singlet oxygenproduction, we can say that this compound is a potential candidate for PDT applications.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	GORDUK S (2021). Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. , 279 - 288. 10.18596/jotcsa.812081
Chicago	GORDUK Semih Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. (2021): 279 - 288. 10.18596/jotcsa.812081
MLA	GORDUK Semih Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. , 2021, ss.279 - 288. 10.18596/jotcsa.812081
AMA	GORDUK S Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. . 2021; 279 - 288. 10.18596/jotcsa.812081
Vancouver	GORDUK S Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. . 2021; 279 - 288. 10.18596/jotcsa.812081
IEEE	GORDUK S "Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy." , ss.279 - 288, 2021. 10.18596/jotcsa.812081
ISNAD	GORDUK, Semih. "Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy". (2021), 279-288. https://doi.org/10.18596/jotcsa.812081

APA	GORDUK S (2021). Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. Journal of the Turkish Chemical Society, Section A: Chemistry, 8(1), 279 - 288. 10.18596/jotcsa.812081
Chicago	GORDUK Semih Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. Journal of the Turkish Chemical Society, Section A: Chemistry 8, no.1 (2021): 279 - 288. 10.18596/jotcsa.812081
MLA	GORDUK Semih Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. Journal of the Turkish Chemical Society, Section A: Chemistry, vol.8, no.1, 2021, ss.279 - 288. 10.18596/jotcsa.812081
AMA	GORDUK S Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. Journal of the Turkish Chemical Society, Section A: Chemistry. 2021; 8(1): 279 - 288. 10.18596/jotcsa.812081
Vancouver	GORDUK S Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy. Journal of the Turkish Chemical Society, Section A: Chemistry. 2021; 8(1): 279 - 288. 10.18596/jotcsa.812081
IEEE	GORDUK S "Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy." Journal of the Turkish Chemical Society, Section A: Chemistry, 8, ss.279 - 288, 2021. 10.18596/jotcsa.812081
ISNAD	GORDUK, Semih. "Investigation of Singlet Oxygen Production Property of Peripherally Tetra-substituted In(III)CI Phthalocyanine for Photodynamic Therapy". Journal of the Turkish Chemical Society, Section A: Chemistry 8/1 (2021), 279-288. https://doi.org/10.18596/jotcsa.812081