Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?

Yıl: 2021 Cilt: 33 Sayı: 1 Sayfa Aralığı: 42 - 45 Metin Dili: İngilizce DOI: 10.5505/agri.2018.30316 İndeks Tarihi: 03-05-2021

Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?

Öz:
Trigeminal neuralgia attributed to multiple sclerosis (TNMS) occurs in 2% to 5% of patients with multiple sclerosis (MS). Although treatment strategies are similar to those for classic trigeminal neuralgia, TNMS tends to become medically resistantand require polytherapy. Demyelinating lesions in critical regions are the most common etiology. However, therapies used totreat MS may trigger trigeminal neuralgia, as well as other pain disorders, like migraines or daily headaches. Presently reportedis the case of a patient with MS who suffered severe trigeminal neuralgia 5 months after switching to teriflunomide, an oralimmunomodulator drug approved for relapsing-remitting MS, and a discussion of possible etiological factors for the development of trigeminal neuralgia.
Anahtar Kelime:

Multipl sklerozlu bir hastada trigeminal nevralji: Rastlantısal? Bir atak? Teriflunomid kaynaklı?

Öz:
Multipl skleroza bağlı trigeminal nevralji (TNMS), multipl skleroz (MS) hastalarının %2–5’inde görülür. Tedavi stratejileri klasik trigeminal nevralji ile benzer olsa da, TNMS medikal tedaviye dirençli hale gelebilir ve çoklu tedavi ihtiyacı doğabilir. Kritik bölgelerdeki demiyelinizan lezyonlar en sık etiyolojidir. Ancak MS tedavisinde kullanılan terapiler, migren ya da günlük başağrısı benzeri diğer ağrı bozuklukları gibi trigeminal nevraljiyi de tetikleyebilmektedir. Burada relaps- remisyonlar ile giden MS için onaylanmış bir oral immunmodulatuvar ilaç olan ‘teriflunomid’e geçtikten beş ay sonra trigeminal nevralji gelişmiş bir MS vakası bildirilmiştir. Vakada trigeminal nevralji için olası etiyolojiler tartışılmıştır.
Anahtar Kelime:

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APA diker s (2021). Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. , 42 - 45. 10.5505/agri.2018.30316
Chicago diker sevda Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. (2021): 42 - 45. 10.5505/agri.2018.30316
MLA diker sevda Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. , 2021, ss.42 - 45. 10.5505/agri.2018.30316
AMA diker s Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. . 2021; 42 - 45. 10.5505/agri.2018.30316
Vancouver diker s Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. . 2021; 42 - 45. 10.5505/agri.2018.30316
IEEE diker s "Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?." , ss.42 - 45, 2021. 10.5505/agri.2018.30316
ISNAD diker, sevda. "Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?". (2021), 42-45. https://doi.org/10.5505/agri.2018.30316
APA diker s (2021). Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. Ağrı, 33(1), 42 - 45. 10.5505/agri.2018.30316
Chicago diker sevda Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. Ağrı 33, no.1 (2021): 42 - 45. 10.5505/agri.2018.30316
MLA diker sevda Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. Ağrı, vol.33, no.1, 2021, ss.42 - 45. 10.5505/agri.2018.30316
AMA diker s Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. Ağrı. 2021; 33(1): 42 - 45. 10.5505/agri.2018.30316
Vancouver diker s Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?. Ağrı. 2021; 33(1): 42 - 45. 10.5505/agri.2018.30316
IEEE diker s "Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?." Ağrı, 33, ss.42 - 45, 2021. 10.5505/agri.2018.30316
ISNAD diker, sevda. "Trigeminal neuralgia in a patient with multiple sclerosis: Coincidental? An attack? Teriflunomide-induced?". Ağrı 33/1 (2021), 42-45. https://doi.org/10.5505/agri.2018.30316