Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis

Gul, Deniz; akpancar, serkan; ERDEM, Yusuf Can

doi:10.5152/tjsm.2020.153

Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis

Yusuf Can ERDEM, (Gülhane Eğitim ve Araştırma Hastanesi, Ortopedi ve Travmatoloji Kliniği, Ankara, Türkiye)

Deniz GÜL, (Tokat Devlet Hastanesi, Ortopedi ve Travmatoloji Bölümü, Tokat, Türkiye)

Serkan AKPANCAR (Tokat Devlet Hastanesi, Ortopedi ve Travmatoloji Bölümü, Tokat, Türkiye)

Spor Hekimliği Dergisi

4 1

Yıl: 2020 Cilt: 55 Sayı: 1 Sayfa Aralığı: 6 - 13 Metin Dili: İngilizce DOI: 10.5152/tjsm.2020.153 İndeks Tarihi: 30-04-2021

Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis

Öz:

Objective: The aim of the present study was to compare the effectiveness ofintraarticular injections of hyaluronic acid (HA) versus dextrose (DX) in combinationwith periarticular prolotherapy (PrT) in the treatment of recreational athletes with kneeosteoarthritis.Material and Methods: A total of 54 patients who had chronic knee osteoarthritis (OA)were included in the study. The patients were divided into two groups as PrT+HA(intraarticular hyaluronic acid combined with periarticular prolotherapy, n=27) andPrT+DX (intraarticular dextrose combined with periarticular prolotherapy, n=27). Clinicalefficacy and pain were evaluated via the Visual Analog Scale (VAS) and the WesternOntario and McMaster Universities Arthritis Index (WOMAC) at pre-treatment and one,three and six-month follow-ups.Results: Intra-group statistical analyses revealed significant improvements in PrT+HAand PrT+DX groups for WOMAC and VAS scores compared with baseline (p<0.001).When the two groups were compared, VAS and WOMAC scores in the first monthfollow-ups were significantly better in the PrT+DX group (p=0.022 and p=0.03,respectively) while sixth month follow-up scores were significantly better in the PrT+HAgroup (p<0.001 and p<0.005 respectively).Conclusions: Both of the intraarticular injections (HA and DX) are efficacious and safein treating knee osteoarthritis. HA offers advantage of higher treatment success, whileDX offers clinical efficacy with less cost.

Anahtar Kelime:

Rekreasyonel Sporcularda Diz Osteoartriti Tedavisinde Periartiküler Proloterapi ile Birlikte Uygulanan İntraartiküler Dekstroz ve Hiyalüronik Asit Enjeksiyonlarının Etkinliğinin Karşılaştırılması

Öz:

Amaç: Bu çalışmanın amacı, rekreasyonel sporculardaki diz osteoartritinin tedavisinde periartiküler proloterapi (PrT) ile birlikte uygulanan eklem içi hiyalüronik asit (HA) ve dekstroz (DX) enjeksiyonlarının etkinliğini karşılaştırmaktır. Gereç ve Yöntemler: Kronik diz osteoartriti (OA) olan toplam 54 hasta çalışmaya dahil edildi. Hastalar PrT+HA (periartiküler PrT ile kombine intraartiküler HA, n=27) ve PrT+DX (periartiküler PrT ile kombine intraartiküler DX, n=27) olarak iki gruba ayrıldı. Klinik etkinlik ve ağrı, Visual Analog Skala (VAS) ve Western Ontario ve McMaster Üniversitesi Artrit İndeksi (WOMAC) kullanılarak tedavi öncesi, bir, üç ve altı aylık izlemlerle değerlendirildi. Bulgular: Grup içi değerlendirmede her iki grupta da WOMAC ve VAS skorlarında tedavi öncesine göre anlamlı iyileşme gözlendi (p<0.001). Gruplar arası karşılaştırmada, VAS ve WOMAC skorları ilk ay takipleri PrT+DX grubunda anlamlı olarak daha iyi iken (sırasıyla p=0.022 ve p=0.03), altıncı ay takiplerde PrT+HA grubunda daha iyi olarak saptandı (sırasıyla p<0.001 ve p<0.005). Sonuç: Her iki intraartiküler enjeksiyon yöntemi de (HA ve DX), diz osteoartritinin tedavisinde etkili ve güvenlidir. HA, daha yüksek tedavi başarısı avantajı, DX ise daha az maliyetle anlamlı klinik etkinlik sunmaktadır.

Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık

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APA	ERDEM Y, Gul D, akpancar s (2020). Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. , 6 - 13. 10.5152/tjsm.2020.153
Chicago	ERDEM Yusuf Can,Gul Deniz,akpancar serkan Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. (2020): 6 - 13. 10.5152/tjsm.2020.153
MLA	ERDEM Yusuf Can,Gul Deniz,akpancar serkan Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. , 2020, ss.6 - 13. 10.5152/tjsm.2020.153
AMA	ERDEM Y,Gul D,akpancar s Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. . 2020; 6 - 13. 10.5152/tjsm.2020.153
Vancouver	ERDEM Y,Gul D,akpancar s Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. . 2020; 6 - 13. 10.5152/tjsm.2020.153
IEEE	ERDEM Y,Gul D,akpancar s "Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis." , ss.6 - 13, 2020. 10.5152/tjsm.2020.153
ISNAD	ERDEM, Yusuf Can vd. "Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis". (2020), 6-13. https://doi.org/10.5152/tjsm.2020.153

APA	ERDEM Y, Gul D, akpancar s (2020). Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. Spor Hekimliği Dergisi, 55(1), 6 - 13. 10.5152/tjsm.2020.153
Chicago	ERDEM Yusuf Can,Gul Deniz,akpancar serkan Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. Spor Hekimliği Dergisi 55, no.1 (2020): 6 - 13. 10.5152/tjsm.2020.153
MLA	ERDEM Yusuf Can,Gul Deniz,akpancar serkan Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. Spor Hekimliği Dergisi, vol.55, no.1, 2020, ss.6 - 13. 10.5152/tjsm.2020.153
AMA	ERDEM Y,Gul D,akpancar s Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. Spor Hekimliği Dergisi. 2020; 55(1): 6 - 13. 10.5152/tjsm.2020.153
Vancouver	ERDEM Y,Gul D,akpancar s Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis. Spor Hekimliği Dergisi. 2020; 55(1): 6 - 13. 10.5152/tjsm.2020.153
IEEE	ERDEM Y,Gul D,akpancar s "Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis." Spor Hekimliği Dergisi, 55, ss.6 - 13, 2020. 10.5152/tjsm.2020.153
ISNAD	ERDEM, Yusuf Can vd. "Comparison of Intraarticular Injections of Hyaluronic Acid versus Dextrose Applied with Periarticular Prolotherapy in the Treatment of Recreational Athletes with Knee Osteoarthritis". Spor Hekimliği Dergisi 55/1 (2020), 6-13. https://doi.org/10.5152/tjsm.2020.153