Yıl: 2021 Cilt: 9 Sayı: 1 Sayfa Aralığı: 53 - 60 Metin Dili: İngilizce DOI: 10.32596/ejcm.galenos.2021-01-09 İndeks Tarihi: 30-04-2021

Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses

Öz:
Objectives: Several risk scoring systems have been validated for cardiovascular risk prediction and prognosis. Periarterial adipose tissue intima media adventitia (PATIMA) index combining carotid intima media thickness (CIMT), carotid extra media thickness (CEMT), cardiac epicardial fat thickness (EFT), and body mass index (BMI) are related to coronary artery disease (CAD).Materials and Methods: One-hundred-twenty-four patients were categorized as low synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) (<22) (n=84) or high SYNTAX (≥22) (n=40) score groups. Association of PATIMA index and its components with SYNTAX score were analyzed.Results: CIMT, CEMT, BMI, EFT, and PATIMA index were not significantly different between groups. SYNTAX score was not significantly correlated with traditional CVS risk factors (diabetes, hypertension, hyperlipidemia, smoking, age). There was a significant correlation between the PATIMA index and age (r=0.308, p=0.001) but not with other risk factors. Age was significantly correlated with CIMT (r=0.289, p=0.001) and EFT (r=0.208, p=0.02) but not with CEMT (r=0.091, p=0.313). There was a significant correlation between CIMT and CEMT (r=0.414, p<0.001) and between CIMT and EFT (r=0.267, p=0.004).Conclusion: We have found that the recently described PATIMA index and its components, CIMT, CEMT, and EFT are not associated with the severity of CAD assessed by the SYNTAX score. Furthermore, they have not correlated with classical risk factors apart from age.
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  • 1. Mitchell Jr, Schwartz Cj. Relationship between arterial disease in different sites. A study of the aorta and coronary, carotid, and iliac arteries. Br Med J 1962;1:1293-301
  • 2. Demirel ME, Donmez I, Ucaroglu ER, Yuksel A. Acute coronary syndromes and diagnostic methods. Med Res Innov 2019;3:1-8.
  • 3. Feinleib M, Kannel WB, Garrison RJ, McNamara PM, Castelli WP. The Framingham Offspring Study. Design and preliminary data. Prev Med 1975;4:518-25.
  • 4. Conroy RM, Pyörälä K, Fitzgerald AP, et al. Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. Eur Heart J 2003;24:987-1003.
  • 5. Assmann G, Cullen P, Schulte H. Simple scoring scheme for calculating the risk of acute coronary events based on the 10-year follow-up of the prospective cardiovascular Münster (PROCAM) study. Circulation 2002;105:310-5.
  • 6. Alipour M, Masri D, Mofazzali A, Chitsazan M. Carotid artery intimamedia thickness in patients undergoing coronary artery bypass graft surgery. Arch Cardiovasc Imaging 2013;1:27-31.
  • 7. Skilton MR, Sérusclat A, Sethu AH, et al. Noninvasive measurement of carotid extra-media thickness: associations with cardiovascular risk factors and intima-media thickness. JACC Cardiovasc Imaging 2009;2:176-82.
  • 8. Haberka M, Gąsior Z. A carotid extra-media thickness, PATIMA combined index and coronary artery disease: Comparison with well-established indexes of carotid artery and fat depots. Atherosclerosis 2015;243:307-13.
  • 9. Korkmaz L, Bektas H, Korkmaz AA, et al. Increased carotid intimamedia thickness is associated with higher SYNTAX score. Angiology 2012;63:386-9.
  • 10. Ikeda N, Kogame N, Iijima R, Nakamura M, Sugi K. Carotid artery intimamedia thickness and plaque score can predict the SYNTAX score. Eur Heart J 2012;33:113-9.
  • 11. Ikeda N, Saba L, Molinari F, et al. Automated carotid intima-media thickness and its link for prediction of SYNTAX score in Japanese coronary artery disease patients. Int Angiol 2013;32:339-48.
  • 12. SYNTAX score calculator. Available at: http://www.SYNTAXscore.com. SYNTAX working-group. Accessed May 2013.
  • 13. Perk J, De Backer G, Gohlke H, et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 2012;33:1635-701.
  • 14. World Health Organization (WHO) Consultation, Definition and Diagnosis of Diabetes and Intermediate Hyperglycaemia, 2006; p. 1-50.
  • 15. World Health Organization (WHO), Abbreviated Report of a WHO Consultation. Use of Glycated Hemoglobin (HbA1c) in the Diagnosis if Diabetes Mellitus, 2011. p.1-25.
  • 16. British Cardiac Society; British Hypertension Society; Diabetes UK; HEART UK; Primary Care Cardiovascular Society; Stroke Association. JBS 2: Joint British Societies’ guidelines on prevention of cardiovascular disease in clinical practice. Heart 2005;91:v1-52.
  • 17. National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-421.
  • 18. Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:307-10.
  • 19. Iacobellis G, Assael F, Ribaudo MC, et al. Epicardial fat from echocardiography: a new method for visceral adipose tissue prediction. Obes Res 2003;11:304-10.
  • 20. Sianos G, Morel MA, Kappetein AP, et al. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention 2005;1:219-27.
  • 21. Valgimigli M, Serruys PW, Tsuchida K, et al. Cyphering the complexity of coronary artery disease using the syntax score to predict clinical outcome in patients with three-vessel lumen obstruction undergoing percutaneous coronary intervention. Am J Cardiol 2007;99:1072-81.
  • 22. Lemesle G, Bonello L, de Labriolle A, et al. Prognostic value of the Syntax score in patients undergoing coronary artery bypass grafting for threevessel coronary artery disease. Catheter Cardiovasc Interv 2009;73:612-7.
  • 23. Capodanno D, Di Salvo ME, Cincotta G, Miano M, Tamburino C, Tamburino C. Usefulness of the SYNTAX score for predicting clinical outcome after percutaneous coronary intervention of unprotected left main coronary artery disease. Circ Cardiovasc Interv 2009;2:302-8.
  • 24. Birim O, van Gameren M, Bogers AJ, Serruys PW, Mohr FW, Kappetein AP. Complexity of coronary vasculature predicts outcome of surgery for left main disease. Ann Thorac Surg 2009;87:1097-104.
  • 25. Kablak-Ziembicka A, Tracz W, Przewlocki T, Pieniazek P, Sokolowski A, Konieczynska M. Association of increased carotid intima-media thickness with the extent of coronary artery disease. Heart 2004;90:1286-90.
  • 26. Saedi S, Ghadrdoost B, Pouraliakbar H, Zahedmehr A, Jebelli A. The association between increased carotid intima-media thickness and SYNTAX Score in coronary artery disease: A single center study. Indian Heart J 2018;70:627-9.
  • 27. Costanzo L, Campisano MB, Capodanno D, et al. The SYNTAX score does not predict presence of carotid disease in a multivessel coronary disease population. Catheter Cardiovasc Interv 2014;83:1169-75.
  • 28. Haberka M, Gąsior Z. Carotid extra-media thickness in obesity and metabolic syndrome: a novel index of perivascular adipose tissue: extramedia thickness in obesity and metabolic syndrome. Atherosclerosis 2015;239:169-77.
  • 29. Falk E, Thim T, Kristensen IB. Atherosclerotic plaque, adventitia, perivascular fat, and carotid imaging. JACC Cardiovasc Imaging 2009;2:183-6.
  • 30. Herrmann J, Samee S, Chade A, Rodriguez Porcel M, Lerman LO, Lerman A. Differential effect of experimental hypertension and hypercholesterolemia on adventitial remodeling. Arterioscler Thromb Vasc Biol 2005;25:447-53.
  • 31. Lefferts WK, Sperry SD, Jorgensen RS, et al. Carotid stiffness, extramedia thickness and visceral adiposity in young adults. Atherosclerosis 2017;265:140-6.
  • 32. D’Amico F, Grasso R. Carotid intima-media and extra-media thickness in hypertensive elderly subjects. Journal of Hypertension 2015;33:497.
  • 33. Cai TY, Magnussen C, Haluska B, et al. Carotid extra-medial thickness does not predict adverse cardiovascular outcomes in high-risk adults. Diabetes Metab 2016;42:200-3
  • 34. Haberka M, Lelek M, Bochenek T, et al. Novel combined index of cardiometabolic risk related to periarterial fat improves the clinical prediction for coronary artery disease complexity. Atherosclerosis 2018;268:76-83.
  • 35. Haberka M, Bałys M, Matla M, Kubicius A, Maciejewski Ł, Gąsior Z. Carotid artery stenosis and ultrasound vascular indexes predict the coronary revascularization in patients with high cardiovascular risk scheduled for coronary angiography. Kardiol Pol 2019;77:1028-33.
  • 36. Haberka M, Sosnowski M, Zuziak-Pruska J, Gąsior Z. Extra-media thickness and epicardial fat: Comparison of a novel carotid artery ultrasound index and a well-established cardiac magnetic resonance fat quantification method. Nutr Metab Cardiovasc Dis 2015;25:763-70
APA COSGUN M, Cosgun Z, gunes y, sincer i, Erdal E, Kurtar Mansıroğlu A, Inanir M (2021). Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. , 53 - 60. 10.32596/ejcm.galenos.2021-01-09
Chicago COSGUN MEHMET,Cosgun Zeliha,gunes yilmaz,sincer isa,Erdal Emrah,Kurtar Mansıroğlu Aslı,Inanir Mehmet Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. (2021): 53 - 60. 10.32596/ejcm.galenos.2021-01-09
MLA COSGUN MEHMET,Cosgun Zeliha,gunes yilmaz,sincer isa,Erdal Emrah,Kurtar Mansıroğlu Aslı,Inanir Mehmet Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. , 2021, ss.53 - 60. 10.32596/ejcm.galenos.2021-01-09
AMA COSGUN M,Cosgun Z,gunes y,sincer i,Erdal E,Kurtar Mansıroğlu A,Inanir M Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. . 2021; 53 - 60. 10.32596/ejcm.galenos.2021-01-09
Vancouver COSGUN M,Cosgun Z,gunes y,sincer i,Erdal E,Kurtar Mansıroğlu A,Inanir M Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. . 2021; 53 - 60. 10.32596/ejcm.galenos.2021-01-09
IEEE COSGUN M,Cosgun Z,gunes y,sincer i,Erdal E,Kurtar Mansıroğlu A,Inanir M "Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses." , ss.53 - 60, 2021. 10.32596/ejcm.galenos.2021-01-09
ISNAD COSGUN, MEHMET vd. "Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses". (2021), 53-60. https://doi.org/10.32596/ejcm.galenos.2021-01-09
APA COSGUN M, Cosgun Z, gunes y, sincer i, Erdal E, Kurtar Mansıroğlu A, Inanir M (2021). Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. E Journal of Cardiovascular Medicine, 9(1), 53 - 60. 10.32596/ejcm.galenos.2021-01-09
Chicago COSGUN MEHMET,Cosgun Zeliha,gunes yilmaz,sincer isa,Erdal Emrah,Kurtar Mansıroğlu Aslı,Inanir Mehmet Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. E Journal of Cardiovascular Medicine 9, no.1 (2021): 53 - 60. 10.32596/ejcm.galenos.2021-01-09
MLA COSGUN MEHMET,Cosgun Zeliha,gunes yilmaz,sincer isa,Erdal Emrah,Kurtar Mansıroğlu Aslı,Inanir Mehmet Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. E Journal of Cardiovascular Medicine, vol.9, no.1, 2021, ss.53 - 60. 10.32596/ejcm.galenos.2021-01-09
AMA COSGUN M,Cosgun Z,gunes y,sincer i,Erdal E,Kurtar Mansıroğlu A,Inanir M Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. E Journal of Cardiovascular Medicine. 2021; 9(1): 53 - 60. 10.32596/ejcm.galenos.2021-01-09
Vancouver COSGUN M,Cosgun Z,gunes y,sincer i,Erdal E,Kurtar Mansıroğlu A,Inanir M Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses. E Journal of Cardiovascular Medicine. 2021; 9(1): 53 - 60. 10.32596/ejcm.galenos.2021-01-09
IEEE COSGUN M,Cosgun Z,gunes y,sincer i,Erdal E,Kurtar Mansıroğlu A,Inanir M "Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses." E Journal of Cardiovascular Medicine, 9, ss.53 - 60, 2021. 10.32596/ejcm.galenos.2021-01-09
ISNAD COSGUN, MEHMET vd. "Association of SYNTAX Score withPATIMA Index, Carotid Intima- andExtra- Media Thicknesses". E Journal of Cardiovascular Medicine 9/1 (2021), 53-60. https://doi.org/10.32596/ejcm.galenos.2021-01-09