The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis
Yıl: 2020 Cilt: 21 Sayı: 2 Sayfa Aralığı: 122 - 127 Metin Dili: İngilizce DOI: 10.4274/meandros.galenos.2020.41033 İndeks Tarihi: 06-05-2021
The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis
Öz: Objective: Hyperlipidemia is a known cardiovascular disease risk factor. A common biological mechanism between systemic diseases, such as cardiovascular diseases, and periodontal diseases has been suggested. This study aimed to examine the association between blood lipid profile and the severity of aggressive periodontitis (AgP).Materials and Methods: A total of 32 systemically healthy patients with AgP (24 females and 8 males; mean age 34.78±6.42 years) were consecutively selected. The patients were divided into 2 groups as localised AgP (LAgP) and generalised AgP (GAgP). Monocyte counts, high-density level (HDL) count and monocyte/HDL ratios (MHR) were recorded from the patients’ blood samples. Mean Plaque index, bleeding on probing, periodontal pocket depth and clinical attachment level were recorded before treatment. The relationship between monocyte to HDL ratios and clinical attachment level between the groups were analysed by Spearman correlation. Results: Sixteen GAgP and 16 LagP patients were included in the study. The mean MHR values for the LAgP and GAgP groups were 9.87±2.85 and 13.43±4.64, respectively; there was a statistically significant difference between the groups (p<0.05).Conclusion: The increased MHR values in patients with severe periodontitis may be one of the pathogenic mechanisms underlying the link between periodontal and cardiovascular diseases. Although we observed statistically significant differences between the MHR values in both groups, a larger sample size is needed to confirm the results of this study in the future
Anahtar Kelime: Agresif Periodontitis Hastalarında Enflamasyon Şiddeti ile Monosit-yüksek Yoğunluklu Lipoprotein Oranı Arasındaki İlişki: Retrospektif Analiz
Öz: Amaç: Hiperlipidemi, kardiyovasküler hastalıklar için bilinen bir risk faktörüdür.Kardiyovasküler hastalıklar gibi sistemik durumlar ile periodontal hastalıklararasında ortak bir biyolojik mekanizma olduğu gösterilmiştir. Bu çalışmanın amacı,kan lipid profili ile agresif periodontitis (AgP) şiddeti arasındaki ilişkiyi incelemektir.Gereç ve Yöntemler: AgP tanısı almış toplam 32 sistemik sağlıklı hasta (24 kadın ve 8 erkek; ortalama yaş: 34,78±6,42) çalışmaya dahiledildi. Hastalar lokalize (LAgP) ve generalize agresif periodontitis (GAgP) olarak iki gruba ayrıldı. Hastalardan alınan kan örneklerindemonosit sayıları, yüksek yoğunluklu lipoprotein seviyesi (HDL) sayımı ve monosit/HDL oranları (MHR) kaydedildi. Ortalama plakindeksi, sondlamada kanama, periodontal cep derinliği ve klinik ataşman seviyesi tedavi öncesinde kaydedildi. Monosit ile HDLoranları arasındaki ilişki ile gruplar arasındaki klinik bağlanma düzeyi arasındaki ilişki Spearman korelasyonuyla analiz edildi. Bulgular: On altı GAgP ve 16 LagP hastası çalışmaya dahil edilmiştir. LAgP ve GAgP grupları için ortalama MHR değeri sırasıyla9,87±2,85 ve 13,43±4,64 olarak bulunmuştur ve gruplar arasında istatistiksel olarak anlamlı bir fark bulunmuştur (p<0,05). Sonuç: Şiddetli periodontitisli hastalarda MHR değerlerinde artış, periodontal hastalık ve kardiyovasküler hastalıklar arasındakibağlantıların altında yatan patojenik mekanizmalardan biri olabilir. GAgP grubu arasında MHR değerlerinde istatistiksel olarakanlamlı farklılıklar gözlemlemiş olsak da, bu çalışmanın sonuçlarını doğrulamak için daha büyük bir örneklem büyüklüğü ile gelecekteyapılacak araştırmalara ihtiyaç vardır.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | GÜLER B, DOĞAN E, Onbasi K (2020). The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. , 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| Chicago | GÜLER Berceste,DOĞAN Ezgi,Onbasi Kevser The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. (2020): 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| MLA | GÜLER Berceste,DOĞAN Ezgi,Onbasi Kevser The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. , 2020, ss.122 - 127. 10.4274/meandros.galenos.2020.41033 |
| AMA | GÜLER B,DOĞAN E,Onbasi K The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. . 2020; 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| Vancouver | GÜLER B,DOĞAN E,Onbasi K The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. . 2020; 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| IEEE | GÜLER B,DOĞAN E,Onbasi K "The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis." , ss.122 - 127, 2020. 10.4274/meandros.galenos.2020.41033 |
| ISNAD | GÜLER, Berceste vd. "The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis". (2020), 122-127. https://doi.org/10.4274/meandros.galenos.2020.41033 |
| APA | GÜLER B, DOĞAN E, Onbasi K (2020). The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. Meandros Medical And Dental Journal, 21(2), 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| Chicago | GÜLER Berceste,DOĞAN Ezgi,Onbasi Kevser The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. Meandros Medical And Dental Journal 21, no.2 (2020): 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| MLA | GÜLER Berceste,DOĞAN Ezgi,Onbasi Kevser The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. Meandros Medical And Dental Journal, vol.21, no.2, 2020, ss.122 - 127. 10.4274/meandros.galenos.2020.41033 |
| AMA | GÜLER B,DOĞAN E,Onbasi K The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. Meandros Medical And Dental Journal. 2020; 21(2): 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| Vancouver | GÜLER B,DOĞAN E,Onbasi K The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis. Meandros Medical And Dental Journal. 2020; 21(2): 122 - 127. 10.4274/meandros.galenos.2020.41033 |
| IEEE | GÜLER B,DOĞAN E,Onbasi K "The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis." Meandros Medical And Dental Journal, 21, ss.122 - 127, 2020. 10.4274/meandros.galenos.2020.41033 |
| ISNAD | GÜLER, Berceste vd. "The Relationship Between MonocyteCount to High-density LipoproteinRatio and Severity of Inflammation inAggressive Periodontitis:A Retrospective Analysis". Meandros Medical And Dental Journal 21/2 (2020), 122-127. https://doi.org/10.4274/meandros.galenos.2020.41033 |
