WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?

Yıl: 2021 Cilt: 84 Sayı: 1 Sayfa Aralığı: 1 - 8 Metin Dili: İngilizce DOI: 10.26650/IUITFD.2020.0091 İndeks Tarihi: 06-05-2021

WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?

Öz:
Objective: Our study aimed to determine the factors related tofrailty in elderly adults having been diagnosed with type 2 diabetes mellitus.Material and Method: A total of 108 people aged 65 and over,diagnosed with type 2 diabetes, were included in the study. Thefrailty of the participants was evaluated with the FRAIL questionnaire, their nutritional status was evaluated with the Mini Nutrition Assessment Short Form (MNA-SF), the depression statuswith the Patient Health Questionnaire-2 (PHQ2) and the Geriatric Depression Scale Short Form (GDS-SF), while the quality oflife was evaluated with the EuroQol-5 Dimension (EQ5D) andScoring the EQ-VAS, and personal care status were evaluatedwith Basic Activities of Daily Living (BADL) and Instrumental Activities of Daily Living (IADL) forms.Results: Sleep problems, fear of falling, presence of urinary incontinence, PHQ2, GDS-SF, and EQ5D scores were significantly higher; the MNASF score was significantly lower in the frailgroup than the values in the non-frail group (p<0.05, for all).Conclusion: The relationship between frailty and malnutrition,decreased quality of life, and increased depression in elderlydiabetic patients was demonstrated in the present study. Asall these factors have a place in the management of diabetes, awareness should be raised and frailty screening should be expanded in elderly diabetics
Anahtar Kelime:

TİP 2 DİYABETLİ YAŞLI BİREYLERDE KIRILGANLIĞI ETKİLEYEN FAKTÖRLER NELERDİR?

Öz:
Amaç: Çalışmamızın amacı tip 2 diyabet tanısı almış yaşlı erişkinlerde kırılganlıkla ilgili faktörleri belirlemektir. Gereç ve Yöntem: Çalışmaya 65 yaş ve üstü, tip 2 diyabet tanısı almış 108 kişi dahil edildi. Katılımcıların kırılganlığı FRAIL anketi ile değerlendirilmiş, beslenme durumu Mini Beslenme Değerlendirme Kısa Formu (MNA-SF) ile, depresyon durumu Hasta Sağlığı Anketi-2 (PHQ2) ve Geriatrik Depresyon Ölçeği Kısa Formu (GDS-SF) ile değerlendirilirken, yaşam kalitesi EuroQol-5 Boyut (EQ5D) ve EQ VAS puanlaması ile, kişisel bakım durumları ise Günlük Yaşamın Temel Aktiviteleri (BADL) ve Günlük Yaşamın Enstrümantal Aktiviteleri (IADL) formları ile değerlendirilmiştir. Bulgular: Kırılgan grupta, kırılgan olmayanlara göre uyku sorunları, düşme korkusu, idrar kaçırma, PHQ2, GDS-SF ve EQ5D skorları anlamlı olarak yüksek; MNASF skoru ise anlamlı olarak düşüktü (p<0,05, tüm kıyaslamalar için). Sonuç: Bu çalışmada yaşlı diyabetik hastalarda kırılganlık ile malnütrisyon, azalan yaşam kalitesi ve artmış depresyon arasındaki ilişki gösterilmiştir. Tüm bu faktörlerin diyabet yönetiminde bir yeri olduğu için farkındalık artırılmalı ve yaşlı diyabetlilerde kırılganlık taraması genişletilmelidir.
Anahtar Kelime:

Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
  • Kinsella K, Wan H. Census Bureau: International Population Reports. An Aging World: 2008, Washington: U.S. Government Printing Office, DC, (serial online) 2009 (cited 2020 January 04). Available from: URL: https://www.census. gov/prod/2009pubs/p95-09-1.pdf.
  • HelpAge International. State of the world’s older people 2002, (serial online) 2002 (cited 2020 January 02). Available from: URL: http://www.helpage.org/Researchandpolicy/ Stateoftheworldsolderpeople/.
  • Turkiye Istatistik Kurumu. Yıllara, Yaş grubu ve cinsiyete göre nüfus- genel nüfus sayımları, (serial online) 2019 (cited 2020 March 03). Available from: URL: http://www.tuik.gov.tr/ UstMenu.do?metod:temelist/
  • Satman İ. Diabetes mellitus tanı ve izleminde yeni kriterler ve belirlenme gerekçeleri. Turkiye Klinikleri J Int Med Sci 2007;3(3):1-15.
  • King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998;21(9):1414-31. [CrossRef]
  • Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87(1):4-14. [CrossRef]
  • Steyn NP, Mann J, Bennett PH, Temple N, Zimmet P, Tuomilehto J, et al. Diet, nutrition, and the prevention of type 2 diabetes. Public Health Nutr 2004;7(1A):147-65. [CrossRef]
  • Ikwuobe J, Bellary S, Griffiths HR. Innovative biomarkers for predicting type 2 diabetes mellitus: relevance to dietary management of frailty in older adults. Biogerontology 2016;17(3):511-27. [CrossRef]
  • Satman I, Omer B, Tutuncu Y, Kalaca S, Gedik S, Dinccag N, et al. Twelve-year trends in the prevalence and risk factors of diabetes and prediabetes in Turkish adults. Eur J Epidemiol 2013;28(2):169-80. [CrossRef]
  • International Diabetes Federation. IDF Diabetes Atlas 6th edition (serial online) 2013 (cited 2020 March 03). Available from: URL: https://www.idf.org/e-library/epidemiologyresearch/diabetes-atlas/19-atlas-6th-edition.html/.
  • International Diabetes Federation. IDF Diabetes Atlas 8th edition (serial online) 2017 (cited 2020 March 03). Available from: URL: http://diabetesatlas.org/IDF_Diabetes_ Atlas_8e_interactive_EN/.
  • Ozdemir S, Öztürk ZA, Türkbeyler İH, Şirin F, Göl M. Klinikte Yatan Geriatrik Hastalarda Farklı Ölçekler Kullanılarak Kırılganlık Prevalansının Belirlenmesi. KSU Medical Journal 2017;12(3):1-5. [CrossRef]
  • Casals C, Casals Sánchez JL, Suárez Cadenas E, AguilarTrujillo MP, Estébanez Carvajal FM, Vázquez-Sánchez MÁ. Frailty in older adults with type 2 diabetes mellitus and its relation with glucemic control, lipid profile blood pressure, balance, disability grade and nutritional status. Nutr Hosp 2018;35(4):820-826.
  • Cobo A, Vázquez LA, Reviriego J, Rodríguez-Mañas L. Impact of frailty in older patients with diabetes mellitus: An overview. Endocrinol Nutr 2016;63(6):291-303. [CrossRef]
  • Chao CT, Wang J, Chien KL. Cohort of Geriatric Nephrology in NTUH (COGENT) study group. Both pre-frailty and frailty increase healthcare utilization and adverse health outcomes in patients with type 2 diabetes mellitus. Cardiovasc Diabetol 2018;17(1):130. [CrossRef]
  • Chode S, Malmstrom TK, Miller DK, Morley JE. Frailty, diabetes, and mortality in middle-aged African Americans. J Nutr Health Aging 2016;20(8):854-9. [CrossRef]
  • Morley JE, Malmstrom TK, Miller DK. A simple frailty questionnaire (FRAIL) predicts outcomes in middle aged African Americans. The Journal of Nutrition, Health & Aging 2012;16(7):601-8. [CrossRef]
  • Fried LP, Tangen CM, Walston J, Newman AB, Hirsch C, Gottdiener J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56(3):M146- 56. [CrossRef]
  • Kaiser MJ, Bauer JM, Ramsch C, Uter W, Guigoz Y, Cederholm T, et al. Validation of the Mini Nutritional Assessment short-form (MNA-SF): a practical tool for identification of nutritional status. J Nutr Health Aging 2009;13(9):782-8. [CrossRef]
  • McManus D, Pipkin SS, Whooley MA. Screening for depression in patients with coronary heart disease (data from the Heart and Soul Study). Am J Cardiol 2005;96(8):1076-81. [CrossRef]
  • Lelito RH, Palumbo LO, Hanley M. Psychometric evaluation of a brief geriatric depression screen. Aging & Mental Health 2001;5(4):387-93. [CrossRef]
  • EuroQol Group: EuroQol--a new facility for the measurement of health-related quality of life. Health Policy 1990;16(3):199-208. [CrossRef]
  • Izumi M, Akifusa S, Ganaha S, Yamashita Y. Activities of daily living decline is a predictor of lowered coughing ability and correlates with rehabilitative effect of tongue cleaning on coughing ability. Odontology 2019;107(1):393-400. [CrossRef]
  • Cho CY, Alessi CA, Cho M, Aronow HU, Stuck AE, Rubenstein LZ, et al. The association between chronic illness and functional change among participants in a comprehensive geriatric assessment program. J Am Geriatr Soc 1998;46(6):677-82. [CrossRef]
  • Siriwardhana DD, Hardoon S, Rait G, Weerasinghe MC, Walters KR. Prevalence of frailty and prefrailty among community-dwelling older adults in low-income and middle-income countries: a systematic review and metaanalysis. BMJ Open 2018;8(3):e018195. [CrossRef]
  • Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc 2012;60(8):1487-92. [CrossRef]
  • Saum KU, Dieffenbach AK, Muller H, Holleczek B, Hauer K, Brenner H. Frailty prevalence and 10-year survival in community-dwelling older adults: results from the ESTHER cohort study. Eur J Epidemiol 2014;29(3):171-9. [CrossRef]
  • Perkisas S, Vandewoude M. Where frailty meets diabetes. Diabetes Metab Res Rev 2016;32(1):261-7. [CrossRef]
  • Acosta-Benito MA, Sevilla-Machuca I. Using prefrailty to detect early disability. J Family Community Med 2016;23(3):140-4. [CrossRef]
  • Kojima G, Iliffe S, Taniguchi Y, Shimada H, Rakugi H, Walters K. Prevalence of frailty in Japan: A systematic review and meta-analysis. J Epidemiol 2017;27(8):347-53. [CrossRef]
  • Li Y, Zou Y, Wang S, Li J, Jing X, Yang M, et al. A Pilot Study of the FRAIL Scale on Predicting Outcomes in Chinese Elderly People With Type 2 Diabetes. J Am Med Dir Assoc 2015;16(8):714.e7-714.e12. [CrossRef]
  • Nishimura A, Harashima SI, Hosoda K, Arai H, Inagaki N. Sex-related differences in frailty factors in older persons with type 2 diabetes: a cross-sectional study. Ther Adv Endocrinol Metab 2019;10:2042018819833304. [CrossRef]
  • Gordon EH, Peel NM, Samanta M, Theou O, Howlett SE, Hubbard RE. Sex differences in frailty: A systematic review and meta-analysis. Exp Gerontol 2017;89:30-40. [CrossRef]
  • Moreira BS, Sampaio RF, Diz JB, Bastone AC, Ferriolli E, Neri AL, et al. Factors associated with fear of falling in community-dwelling older adults with and without diabetes mellitus: Findings from the Frailty in Brazilian Older People Study (FIBRA-BR). Exp Gerontol 2017;89:103-11. [CrossRef]
  • Ensrud KE, Blackwell TL, Redline S, Ancoli-Israel S, Paudel ML, Cawthon PM, et al. Sleep disturbances and frailty status in older community-dwelling men. J Am Geriatr Soc 2009;57(11):2085-93. [CrossRef]
  • Suskind AM. Frailty and Lower Urinary Tract Symptoms. Curr Urol Rep 2017;18(9):67. [CrossRef]
  • Kondrup J, Allison S, Elia M, Vellas B, Plauth M. ESPEN Guidelines for Nutrition Screening 2002. Clin Nutr 2003;22(4):415-21. [CrossRef]
  • Rubenstein L, Harker j, Salva A, Guigoz Y, Vellas B. Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF). J Gerontol a Biol Med Sci 2001;56(6):366-72. [CrossRef]
  • Helminen H, Luukkaala T, Saarnio J, Nuotio MS. Predictive value of the mini-nutritional assessment short form (MNASF) and nutritional risk screening (NRS2002) in hip fracture. Eur J Clin Nutr 2019;73(1):112-20. [CrossRef]
  • Wei K, Thein FS, Nyunt MSZ, Gao Q, Wee SL, Ng TP. Nutritional and Frailty State Transitions in the Singapore Longitudinal Aging Study. J Nutr Health Aging 2018;22(10):1221-7. [CrossRef]
  • Lorenzo-López L, Maseda A, de Labra C, Regueiro-Folgueira L, Rodríguez-Villamil JL, Millán-Calenti JC. Nutritional determinants of frailty in older adults: A systematic review. BMC Geriatr 2017;17(1):108. [CrossRef]
  • Cruz-Jentoft AJ, Woo J. Nutritional interventions to prevent and treat frailty. Curr Opin Clin Nutr Metab Care 2019;22(3):191-5. [CrossRef]
  • Laur CV, McNicholl T, Valaitis R, Keller HH. Malnutrition or frailty? Overlap and evidence gaps in the diagnosis and treatment of frailty and malnutrition. Appl Physiol Nutr Metab 2017;42(5):449-58. [CrossRef]
  • Soysal P, Veronese N, Thompson T, Kahl KG, Fernandes BS, Prina AM, et al. Relationship between depression and frailty in older adults: A systematic review and meta-analysis. Ageing Res Rev 2017;36:78-87. [CrossRef]
  • Almeida OP, McCaul K, Hankey GJ, Yeap BB, Golledge J, Norman PE, et al. Duration of diabetes and its association with depression in later life: The Health In Men Study (HIMS). Maturitas 2016;86:3-9. [CrossRef]
  • Kojima G, Iliffe S, Jivraj S, Walters K. Association between frailty and quality of life among community-dwelling older people: a systematic review and meta-analysis. J Epidemiol Community Health 2016;70(7):716-21. [CrossRef]
  • Crocker TF, Brown L, Clegg A, Farley K, Franklin M, Simpkins S, et al. Quality of life is substantially worse for communitydwelling older people living with frailty: systematic review and meta-analysis. Qual Life Res 2019;28(8):2041-56. [CrossRef]
  • Kim S, Won CW, Kim BS, Kim S, Yoo J, Byun S, et al. EuroQol Visual Analogue Scale (EQ-VAS) as a Predicting Tool for Frailty in Older Korean Adults: The Korean Frailty an Aging Cohort Study (KFACS). J Nutr Health Aging 2018;22(10):1275-80. [CrossRef]
APA Idiz C, Yilmaz O, Gül N, Tekin S, Cakmak R, Ören M, Gürkaş S, KARAN M, Bahat G, Satman I (2021). WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. , 1 - 8. 10.26650/IUITFD.2020.0091
Chicago Idiz Cemile,Yilmaz Ozlem,Gül Nurdan,Tekin Sakin,Cakmak Ramazan,Ören Merve,Gürkaş Sena,KARAN MEHMET,Bahat Gulistan,Satman Ilhan WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. (2021): 1 - 8. 10.26650/IUITFD.2020.0091
MLA Idiz Cemile,Yilmaz Ozlem,Gül Nurdan,Tekin Sakin,Cakmak Ramazan,Ören Merve,Gürkaş Sena,KARAN MEHMET,Bahat Gulistan,Satman Ilhan WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. , 2021, ss.1 - 8. 10.26650/IUITFD.2020.0091
AMA Idiz C,Yilmaz O,Gül N,Tekin S,Cakmak R,Ören M,Gürkaş S,KARAN M,Bahat G,Satman I WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. . 2021; 1 - 8. 10.26650/IUITFD.2020.0091
Vancouver Idiz C,Yilmaz O,Gül N,Tekin S,Cakmak R,Ören M,Gürkaş S,KARAN M,Bahat G,Satman I WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. . 2021; 1 - 8. 10.26650/IUITFD.2020.0091
IEEE Idiz C,Yilmaz O,Gül N,Tekin S,Cakmak R,Ören M,Gürkaş S,KARAN M,Bahat G,Satman I "WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?." , ss.1 - 8, 2021. 10.26650/IUITFD.2020.0091
ISNAD Idiz, Cemile vd. "WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?". (2021), 1-8. https://doi.org/10.26650/IUITFD.2020.0091
APA Idiz C, Yilmaz O, Gül N, Tekin S, Cakmak R, Ören M, Gürkaş S, KARAN M, Bahat G, Satman I (2021). WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. İstanbul Tıp Fakültesi Dergisi, 84(1), 1 - 8. 10.26650/IUITFD.2020.0091
Chicago Idiz Cemile,Yilmaz Ozlem,Gül Nurdan,Tekin Sakin,Cakmak Ramazan,Ören Merve,Gürkaş Sena,KARAN MEHMET,Bahat Gulistan,Satman Ilhan WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. İstanbul Tıp Fakültesi Dergisi 84, no.1 (2021): 1 - 8. 10.26650/IUITFD.2020.0091
MLA Idiz Cemile,Yilmaz Ozlem,Gül Nurdan,Tekin Sakin,Cakmak Ramazan,Ören Merve,Gürkaş Sena,KARAN MEHMET,Bahat Gulistan,Satman Ilhan WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. İstanbul Tıp Fakültesi Dergisi, vol.84, no.1, 2021, ss.1 - 8. 10.26650/IUITFD.2020.0091
AMA Idiz C,Yilmaz O,Gül N,Tekin S,Cakmak R,Ören M,Gürkaş S,KARAN M,Bahat G,Satman I WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. İstanbul Tıp Fakültesi Dergisi. 2021; 84(1): 1 - 8. 10.26650/IUITFD.2020.0091
Vancouver Idiz C,Yilmaz O,Gül N,Tekin S,Cakmak R,Ören M,Gürkaş S,KARAN M,Bahat G,Satman I WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?. İstanbul Tıp Fakültesi Dergisi. 2021; 84(1): 1 - 8. 10.26650/IUITFD.2020.0091
IEEE Idiz C,Yilmaz O,Gül N,Tekin S,Cakmak R,Ören M,Gürkaş S,KARAN M,Bahat G,Satman I "WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?." İstanbul Tıp Fakültesi Dergisi, 84, ss.1 - 8, 2021. 10.26650/IUITFD.2020.0091
ISNAD Idiz, Cemile vd. "WHAT ARE THE FACTORS AFFECTING THE FRAILTY OF ELDERLY PEOPLE WITH TYPE 2 DIABETES?". İstanbul Tıp Fakültesi Dergisi 84/1 (2021), 1-8. https://doi.org/10.26650/IUITFD.2020.0091