The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients
Yıl: 2020 Cilt: 54 Sayı: 4 Sayfa Aralığı: 148 - 151 Metin Dili: İngilizce DOI: 10.4274/turkderm.galenos.2020.74240 İndeks Tarihi: 21-05-2021
The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients
Öz: Background and Design: Psoriasis is a chronic inflammatory skin condition associated with several systemic comorbidities including cardiovascular diseases (CVD). Epicardial fat pad (EFP) is defined as a visceral fat tissue surrounding the heart and coronary vessels. Recent studies revealed epicardial fat thickness, which is also increased in psoriasis, as an early sign of CVD. The aim of this study was to evaluate EFP prevalence and its associations in psoriasis patients.Materials and Methods: Two hundred thirty-seven psoriasis and 113 control patients were assessed for CVD risk factors, Psoriasis Area Severity Index, body composition parameters and laboratory work-up. Controls were chosen from outpatients who lack any chronic inflammatory skin disease and/or systemic inflammatory disease. Evaluation of chest X-rays were performed by a radiologist who was unaware of clinical data.Results: 42.2% of psoriasis patients (n=100) and 31% of controls (n=35) had EFP detected on chest X-ray revealing psoriasis patients had significantly more prevalent EFP than the controls (p=0.047). Prevalence of major CVD risk factors was statistically higher in psoriasis patients (60%, n=142) compared to controls (32%, n=36), (p<0.01). Psoriasis patients with EFP presented higher prevalence of CVD risk factors (70%, 4, n=69) compared to patients who did not have EFP (53%, n=67) (p=0.009).Conclusion: EFP is associated with concurrent CVD risk factors and is more prevalent in psoriasis. It can be detected by a first-line imaging method like chest X-ray which is quite cheap, easy to perform and applicable to almost each patient.
Anahtar Kelime: Psoriazis hastalarında akciğer grafisi ile tespit edilen epikardiyal yağ yastıkçığı sıklığı
Öz: Amaç: Psoriazis, kardiyovasküler hastalıklar (KVH) için bağımsız bir risk faktörü olarak kabul edilmektedir. Epikardiyal yağ yastıkçığı (EYY) isekalp ve koroner damarları çevreleyen visseral yağ dokusu olarak tanımlanmaktadır. Son dönem çalışmalar, psoriazisli hastalarda artış gösterenepikardiyal yağ kalınlığının KVH için erken bir bulgu olduğuna dikkat çekmektedir. Bu çalışmanın amacı, psoriazis hastalarında EYY ve bununlailişkili durumların prevalansını ortaya koymaktır. Gereç ve Yöntem: Bu çalışmada, 237 psoriazis hastası ve 113 kontrol hastası, KVH risk faktörleri, Psoriazis Alan Şiddeti İndeksi, vücutkompozisyon parametreleri ve laboratuvar verileri açısından karşılaştırmalı olarak değerlendirildi. Kontrol grubu kliniğimizde ayaktan hastapolikliniğine başvuran ve hiçbir sistemik enflamatuvar hastalığı olmayan hastalardan seçildi. Akciğer grafileri klinik veriler açısından kör birradyoloji uzmanı tarafından değerlendirildi. Bulgular: Psoriazis hastalarının %42.2’sinde (n=100) ve kontrol grubunun %31’inde (n=35) akciğer grafisinde EYY tespit edildi. Psoriazisgrubunda, EYY sıklığı kontrol grubuna kıyasla istatistiksel anlamlı şekilde yüksekti (p=0,047). Majör KVH risk faktörleri psoriazis hasta grubunda(%60, n=142), kontrol grubuna (%32, n=36) kıyasla istatistiksel olarak anlamlı şekilde yüksek bulundu (p<0,01). KVH risk faktörleri, EYYolan psoriazis hastalarında (%70, n=69), EYY bulunmayan psoriazis hastalarına (%53, n=67) kıyasla istatistiksel olarak daha yüksek bulundu.(p=0,009). Sonuç: EYY, mevcut KVH risk faktörleri ile ilişkilidir ve psoriazis hastalarında kontrol grubuna kıyasla daha sık gözlenmektedir. Sıklıkla ilk sıradakullanılan, göreceli olarak ucuz ve uygulaması basit bir görüntüleme yöntemi olan akciğer grafisi ile EYY’leri rahatlıkla tespit edilebilmektedir.
Anahtar Kelime: Belge Türü: Makale Makale Türü: Araştırma Makalesi Erişim Türü: Erişime Açık
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| APA | Dogan S, esme p, Gülsün Akpınar M, Atakan N (2020). The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. , 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| Chicago | Dogan Sibel,esme pelin,Gülsün Akpınar Meltem,Atakan Nilgun The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. (2020): 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| MLA | Dogan Sibel,esme pelin,Gülsün Akpınar Meltem,Atakan Nilgun The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. , 2020, ss.148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| AMA | Dogan S,esme p,Gülsün Akpınar M,Atakan N The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. . 2020; 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| Vancouver | Dogan S,esme p,Gülsün Akpınar M,Atakan N The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. . 2020; 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| IEEE | Dogan S,esme p,Gülsün Akpınar M,Atakan N "The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients." , ss.148 - 151, 2020. 10.4274/turkderm.galenos.2020.74240 |
| ISNAD | Dogan, Sibel vd. "The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients". (2020), 148-151. https://doi.org/10.4274/turkderm.galenos.2020.74240 |
| APA | Dogan S, esme p, Gülsün Akpınar M, Atakan N (2020). The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. Türkderm Türk deri hastalıkları ve frengi arşivi, 54(4), 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| Chicago | Dogan Sibel,esme pelin,Gülsün Akpınar Meltem,Atakan Nilgun The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. Türkderm Türk deri hastalıkları ve frengi arşivi 54, no.4 (2020): 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| MLA | Dogan Sibel,esme pelin,Gülsün Akpınar Meltem,Atakan Nilgun The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. Türkderm Türk deri hastalıkları ve frengi arşivi, vol.54, no.4, 2020, ss.148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| AMA | Dogan S,esme p,Gülsün Akpınar M,Atakan N The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. Türkderm Türk deri hastalıkları ve frengi arşivi. 2020; 54(4): 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| Vancouver | Dogan S,esme p,Gülsün Akpınar M,Atakan N The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients. Türkderm Türk deri hastalıkları ve frengi arşivi. 2020; 54(4): 148 - 151. 10.4274/turkderm.galenos.2020.74240 |
| IEEE | Dogan S,esme p,Gülsün Akpınar M,Atakan N "The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients." Türkderm Türk deri hastalıkları ve frengi arşivi, 54, ss.148 - 151, 2020. 10.4274/turkderm.galenos.2020.74240 |
| ISNAD | Dogan, Sibel vd. "The frequency of epicardial fat pads detected by chest x-rays inpsoriasis patients". Türkderm Türk deri hastalıkları ve frengi arşivi 54/4 (2020), 148-151. https://doi.org/10.4274/turkderm.galenos.2020.74240 |
